BlaOXA-10 and PSE-1 Genes Located on Class 1 Integrons in Gallibacterium anatis
To the Editor,
Gallibacterium anatis (G. anatis) is able to cause lesions such as oophoritis, follicle degeneration, salpingitis, peritonitis in chickens, rendering loss in egg production, and increased mortality in egg-laying chickens . Currently, aminoglycosides and beta-lactam antibiotics have been widely used to treat G. anatis infection. However, irrational use of antibiotics can lead to the development of antibiotic resistance. The increasing multi-drug resistance is complicating the treatment of the infections related to G. anatis . However, the mechanism of multi-drug resistant in G. anatis remains poorly understood. Integrons are known to be one of the mobilizable elements that capture external antibiotic resistance gene cassettes and result in the rapid spread of resistance in Gram-negative bacteria . To date, whether integrons and associated resistance genes exist in G. anatis has not been explored in depth.
In the present study, the detection of integrons among 61 G...
The research project was supported by the National Natural Science Foundation of China Grant U1404328, Natural Science Foundation of HeNan Grants 162300410153, and the Science and Technology Innovation Team Project of Henan University of Animal Husbandry and Economy Grants HUAHE2015014.
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Conflict of interest
The author has declared that no competing interests exist.
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