Effects of Roundup® and Glyphosate on Three Food Microorganisms: Geotrichum candidum, Lactococcus lactis subsp. cremoris and Lactobacillus delbrueckii subsp. bulgaricus

Abstract

Use of many pesticide products poses the problem of their effects on environment and health. Amongst them, the effects of glyphosate with its adjuvants and its by-products are regularly discussed. The aim of the present study was to shed light on the real impact on biodiversity and ecosystems of Roundup®, a major herbicide used worldwide, and the glyphosate it contains, by the study of their effects on growth and viability of microbial models, namely, on three food microorganisms (Geotrichum candidum, Lactococcus lactis subsp. cremoris and Lactobacillus delbrueckii subsp. bulgaricus) widely used as starters in traditional and industrial dairy technologies. The presented results evidence that Roundup® has an inhibitory effect on microbial growth and a microbicide effect at lower concentrations than those recommended in agriculture. Interestingly, glyphosate at these levels has no significant effect on the three studied microorganisms. Our work is consistent with previous studies which demonstrated that the toxic effect of glyphosate was amplified by its formulation adjuvants on different human cells and other eukaryotic models. Moreover, these results should be considered in the understanding of the loss of microbiodiversity and microbial concentration observed in raw milk for many years.

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Acknowledgments

The authors thank J.-M. Bré for his technical assistance during the experimentation. This work was supported by the Ministère de l’Enseignement Supérieur et de la Recherche. E. C. holds a fellowship from the Conseil Régional de Basse-Normandie and CRIIGEN (Committee for Independent Research and Information on Genetic Engineering). The authors would also like to thank Testbiotech for their support.

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Correspondence to Jean-Michel Panoff.

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Clair, E., Linn, L., Travert, C. et al. Effects of Roundup® and Glyphosate on Three Food Microorganisms: Geotrichum candidum, Lactococcus lactis subsp. cremoris and Lactobacillus delbrueckii subsp. bulgaricus . Curr Microbiol 64, 486–491 (2012). https://doi.org/10.1007/s00284-012-0098-3

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Keywords

  • Glyphosate
  • Roundup
  • Shikimic Acid
  • Geotrichum Candidum
  • Lactococcus Lactis Subsp