Current Microbiology

, Volume 62, Issue 6, pp 1689–1696 | Cite as

Effect of a Probiotic Intake on Oxidant and Antioxidant Parameters in Plasma of Athletes During Intense Exercise Training

  • Daniele Martarelli
  • Maria Cristina Verdenelli
  • Stefania Scuri
  • Mario Cocchioni
  • Stefania Silvi
  • Cinzia Cecchini
  • Pierluigi Pompei
Article

Abstract

The aim of this study was to evaluate the effect of Lactobacillus rhamnosus IMC 501® and Lactobacillus paracasei IMC 502® on oxidative stress in athletes during a four-week period of intense physical activity. Two groups of twelve subjects each were selected for this analysis. The first group consumed a daily dose of a mixture of the two probiotic strains (1:1 L. rhamnosus IMC 501® and L. paracasei IMC 502®; ~109 cells/day) for 4 weeks. The second group (control) did not consume any supplements during the 4 weeks. Blood samples collected immediately before and after the supplementation were analyzed, and plasma levels of reactive oxygen metabolites and biological antioxidant potential were determined. Faeces were also collected and analyzed before and at the end of the probiotic supplementation. Antioxidative activity and oxidative stress resistance of the two strains were determined in vitro. Results demonstrated that intense physical activity induced oxidative stress and that probiotic supplementation increased plasma antioxidant levels, thus neutralizing reactive oxygen species. The two strains, L. rhamnosus IMC 501® and L. paracasei IMC 502®, exert strong antioxidant activity. Athletes and all those exposed to oxidative stress may benefit from the ability of these probiotics to increase antioxidant levels and neutralize the effects of reactive oxygen species.

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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Daniele Martarelli
    • 1
  • Maria Cristina Verdenelli
    • 2
  • Stefania Scuri
    • 3
  • Mario Cocchioni
    • 3
  • Stefania Silvi
    • 2
  • Cinzia Cecchini
    • 2
  • Pierluigi Pompei
    • 1
  1. 1.School of Pharmacy, Unit of Experimental Medicine and Public HealthUniversity of CamerinoCamerinoItaly
  2. 2.School of Biosciences and BiotechnologiesUniversity of CamerinoCamerinoItaly
  3. 3.School of Pharmacy, Hygiene and Public Health Research CentreUniversity of CamerinoCamerinoItaly

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