Skip to main content

Advertisement

SpringerLink
Log in

Editorial overview: novel concepts in the pathogenesis and therapy of allergy and asthma

  • Original Paper
  • Published:
Springer Seminars in Immunopathology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Umetsu D, McIntire J, Macaubas C, et al (2002) Asthma: an epidemic of dysregulated immunity. Nat Immunol 3:715

    Google Scholar 

  2. Martinez FD, Wright AL, Taussig LM, et al (1995) Asthma and wheezing in the first six years of life. N Engl J Med 332:133

    Google Scholar 

  3. Riedler J, Eder W, Oberfeld G, et al (2000) Austrian children living on a farm have less hay fever, asthma and allergic sensitization. Clin Exp Allergy 30:194

    Google Scholar 

  4. Braun-Fahrlander C, Riedler J, Herz U, et al (2002) Environmental exposure to endotoxin and its relation to asthma in school-age children. N Engl J Med 347:869

    Google Scholar 

  5. Ownby D, Johnson C, Peterson E (2002) Exposure to dogs and cats in the first year of life and risk of allergic sensitization at 6 to 7 years of age. JAMA 288:963

    Google Scholar 

  6. Kalliomaki M, Salminen S, Arvilommi H, et al (2001) Probiotics in primary prevention of atopic disease: a randomised placebo-controlled trial. Lancet 357:1076

    Google Scholar 

  7. Finotto S, Neurath M, Glickman J, et al (2002) Development of spontaneous airway changes consistent with human asthma in mice lacking T-bet. Science 295:336

    Google Scholar 

  8. Akbari O, Stock P, Meyer E, et al (2003) Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity. Nat Med 9:582

    Google Scholar 

  9. McIntire JJ, Umetsu SE, Akbari O, et al (2001) Identification of Tapr (an airway hyperreactivity regulatory locus) and the linked Tim gene family. Nat Immunol 2:1109

    Google Scholar 

  10. McIntire J, Umetsu S, Macaubas C, et al (2003) Immunology: hepatitis A virus link to atopic disease. Nature 425:576

    Google Scholar 

  11. Sharpe AH, Freeman GJ (2002) The B7-CD28 superfamily. Nat Rev Immunol 2:116

    Google Scholar 

  12. Van Eerdewegh P, Little RD, Dupuis J, et al (2002) Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness. Nature 418:426

    Google Scholar 

  13. Moller C, Dreborg S, Ferdousi HA, et al (2002) Pollen immunotherapy reduces the development of asthma in children with seasonal rhinoconjunctivitis (the PAT-study). J Allergy Clin Immunol 109:251

    Google Scholar 

  14. Tighe H, Takabayashi K, Schwartz D, et al (2000) Conjugation of immunostimulatory DNA to the short ragweed allergen amb a 1 enhances its immunogenicity and reduces its allergenicity. J Allergy Clin Immunol 106:124

    Google Scholar 

  15. Hansen G, Yeung VP, Berry G, et al (2000) Vaccination with heat killed listeria as adjuvant reverses established allergen-induced airway hyperreactivity and inflammation: role of CD8+ T cells and IL-18. J Immunol 164:223

    Google Scholar 

  16. Eisenbarth SC, Piggott DA, Huleatt JW, et al (2002) Lipopolysaccharide-enhanced, Toll-like receptor 4-dependent T helper cell type 2 responses to inhaled antigen. J Exp Med 196:1645

    Google Scholar 

  17. Oldfield W, Larche M, Kay A (2002) Effect of T-cell peptides derived from Fel d 1 on allergic reactions and cytokine production in patients sensitive to cats: a randomised controlled trial. Lancet 360:47

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Division of Immunology and Allergy, Stanford University, , Stanford, CA, 94305, USA

    Dale T. Umetsu & Rosemarie H. DeKruyff

Authors
  1. Dale T. Umetsu
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Rosemarie H. DeKruyff
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Dale T. Umetsu.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Umetsu, D.T., DeKruyff, R.H. Editorial overview: novel concepts in the pathogenesis and therapy of allergy and asthma. Springer Semin Immun 25, 231–236 (2004). https://doi.org/10.1007/s00281-003-0155-x

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00281-003-0155-x

Keywords

Search

Navigation