Zusammenfassung
Die Adipositas geht im Erwachsenenalter oft mit psychischer Komorbidität einher, die den Gewichtsreduktionserfolg beeinflussen und eine Behandlung indizieren kann, die von Standardprogrammen der multimodalen Adipositasverhaltenstherapie (AVT) nicht abgedeckt wird. Dieser Artikel diskutiert am Beispiel der häufig komorbiden Binge-Eating-Störung (BES) aktuelle Forschungsergebnisse zu Ätiologie und Intervention bei Komorbidität mit dem Ziel, Implikationen für die weitere Forschung und Behandlung abzuleiten. Die Kognitive Verhaltenstherapie (KVT), die am besten belegte Therapieform für Erwachsene mit BES, war der AVT bei der Reduktion der Essstörungssymptomatik überlegen und bei der Gewichtsreduktion nur tendenziell und ausschließlich kurzfristig unterlegen. Daher sollte sich die weitere Interventionsentwicklung auf graduelle Anpassungen der KVT zur Verbesserung der Gewichtsreduktion bei Patienten mit Adipositas und BES konzentrieren. Hierfür kommen mit dem Ziel einer geringfügigen Gewichtsreduktion einzelne adaptierte AVT-Interventionen in Betracht, während sich gleichzeitige oder sequenzielle Kombinationen dieser beiden Therapieformen nicht eindeutig bewährt haben. Interventionen, die auf aktuellen Forschungsergebnissen für die Komorbidität beider Störungsbilder fußen, könnten individualisiert einbezogen werden, um die Wirksamkeit für Essstörungssymptomatik und Körpergewicht zu erhöhen. Neue digitale Behandlungsmodalitäten könnten den Transfer in den Lebensalltag und die Nachhaltigkeit der Effekte fördern. Diese Modifikationen hin zu einer adaptiven KVT für Erwachsene mit Adipositas und BES, basierend auf einem patientengerechten Therapierational, bedürfen der Absicherung durch weitere experimentelle Therapieforschung.
Abstract
Obesity is often associated with mental comorbidity in adults, likely impacting on weight loss success and can indicate treatment that is not covered by the standard program of multimodal behavioral weight loss (BWL) treatment. Using the example of binge-eating disorder (BED) as a frequent comorbid condition, this article discusses current research on the etiology and interventions in cases of comorbidity in order to derive implications for research and treatment. Cognitive-behavioral therapy (CBT), the best established form of treatment for adults with BED, was more efficacious than BWL treatment in improving binge-eating symptomatology, while tending to show lower weight loss effects and only in the short term. Therefore, further development of interventions should focus on gradual adaptations of CBT for improving weight loss in patients with obesity and BED. These interventions could be adapted from BWL treatment and aim at a slight weight loss. Parallel or sequential combinations of these treatments have not consistently demonstrated improved treatment effects. Interventions based on the results of current research on the comorbidity of both disorders could be included on an individual basis in order to enhance the efficacy for eating disorder symptomatology and body weight. New digital treatment modalities could support the transfer into daily life and boost the long-term sustainability of therapeutic gains. These modifications regarding adaptive CBT for adults with obesity and BED should be based on an individual treatment rationale and require confirmation by further experimental treatment research.
Literatur
American Psychiatric Association (2013) Diagnostic and statistical manual of mental disorders, 5. Aufl. American Psychiatric Association, Arlington
Blüher M (2019) Obesity: global epidemiology and pathogenesis. Nat Rev Endocrinol 15:288–298
Blume M, Schmidt R, Hilbert A (2017) Biofeedback: Stellenwert in der Behandlung von Ess- und Gewichtsstörungen. Psychotherapeut 62:204–211
Brauhardt A, de Zwaan M, Hilbert A (2014) The therapeutic process in psychological treatments for eating disorders: a systematic review. Int J Eat Disord 47:565–584
Bulik CM, Blake L, Austin J (2019) Genetics of eating disorders: what the clinician needs to know. Psychiatr Clin North Am 42:59–73
Cooper Z, Calugi S, Dalle Grave R (2020) Controlling binge eating and weight: a treatment for binge eating disorder worth researching? Eat Weight Disord 25:1105–1109
Czajkowski SM, Powell LH, Adler N, Naar-King S, Reynolds KD, Hunter CM et al (2015) From ideas to efficacy: the ORBIT model for developing behavioral treatments for chronic diseases. Health Psychol 34:971–982
Deutsche Adipositas Gesellschaft (2014) S3-Leitlinie „Prävention und Therapie der Adipositas“. https://www.adipositas-gesellschaft.de/fileadmin/PDF/Leitlinien/050-001l_S3_Adipositas_Praevention_Therapie_2014-11.pdf. Zugegriffen: 1. Okt. 2020
Diabetes Prevention Program Research Group (2015) Long-term effects of lifestyle intervention or metformin on diabetes development and microvascular complications over 15-year follow-up: the Diabetes Prevention Program Outcomes Study. Lancet Diabetes Endocrinol 3:866–875
Effertz T, Engel S, Verheyen F, Linder R (2016) The costs and consequences of obesity in Germany: a new approach from a prevalence and life-cycle perspective. Eur J Health Econ 17:1141–1158
Elks CE, den Hoed M, Zhao JH, Sharp SJ, Wareham NJ, Loos RJ, Ong KK (2012) Variability in the heritability of body mass index: a systematic review and meta-regression. Front Endocrinol 3:29
Giel KE, Teufel M, Junne F, Zipfel S, Schag K (2017) Food-related impulsivity in obesity and binge eating disorder—a systematic update of the evidence. Nutrients 9:1170
Grilo CM, Masheb RM, Wilson GT, Gueorguieva R, White MA (2011) Cognitive-behavioral therapy, behavioral weight loss, and sequential treatment for obese patients with binge-eating disorder: a randomized controlled trial. J Consult Clin Psychol 79:675–685
Grilo CM, White MA, Ivezaj V, Gueorguieva R (2020a) Randomized controlled trial of behavioral weight loss and stepped care for binge-eating disorder: 12-month follow-up. Obesity. https://doi.org/10.1002/oby.22975
Grilo CM, White MA, Masheb RM, Ivezaj V, Morgan PT, Gueorguieva R (2020b) Randomized controlled trial testing the effectiveness of adaptive “SMART” stepped-care treatment for adults with binge-eating disorder comorbid with obesity. Am Psychol 75:204–218
Haedt-Matt AA, Keel PK (2011) Revisiting the affect regulation model of binge eating: a meta-analysis of studies using ecological momentary assessment. Psychol Bull 137:660–681
Hilbert A (2019) Binge-eating disorder. Psychiatr Clin North Am 42:33–43
Hilbert A, Brauhardt A (2014) Childhood loss of control eating over five-year follow-up. Int J Eat Disord 47:758–761
Hilbert A, Tuschen-Caffier B (2010) Essanfälle und Adipositas: Ein Manual zur Kognitiv-Behavioralen Therapie der „Binge-Eating“-Störung. Hogrefe, Göttingen
Hilbert A, Pike KM, Goldschmidt AB, Wilfley DE, Fairburn CG, Dohm FA, Walsh BT, Striegel Weissman R (2014) Risk factors across the eating disorders. Psychiatry Res 220:500–506
Hilbert A, Petroff D, Herpertz S, Pietrowsky R, Tuschen-Caffier B, Vocks S, Schmidt R (2019a) Meta-analysis of the efficacy of psychological and medical treatments for binge-eating disorder. J Consult Clin Psychol 87:91–105
Hilbert A, Herpertz S, Kersting A, Pietrowsky R, Tuschen-Caffier B, Vocks S (2019b) Binge-Eating-Störung. In: Herpertz S, Fichter M, Herpertz-Dahlmann B, Hilbert A, Tuschen-Caffier B, Vocks S, Zeeck A (Hrsg) S3-Leitlinie Diagnostik und Therapie der Essstörungen. Springer, Berlin, S 275–302
Hilbert A, Petroff D, Herpertz S, Pietrowsky R, Tuschen-Caffier B, Vocks S, Schmidt R (2020) Meta-analysis on the long-term effectiveness of psychological and medical treatments for binge-eating disorder. Int J Eat Disord 53:1353–1376
Juarascio AS, Parker MN, Lagacey MA, Godfrey KM (2018) Just-in-time adaptive interventions: a novel approach for enhancing skill utilization and acquisition in cognitive behavioral therapy for eating disorders. Int J Eat Disord 51:826–830
Kittel R, Brauhardt A, Hilbert A (2015) Cognitive and emotional functioning in binge-eating disorder: a systematic review. Int J Eat Disord 48:535–554
Kober H, Boswell RG (2018) Potential psychological and neural mechanisms in binge eating disorder: implications for treatment. Clin Psychol Rev 60:32–44
LeBlanc ES, Patnode CD, Webber EM, Redmond N, Rushkin M, O’Connor EA (2018) Behavioral and pharmacotherapy weight loss interventions to prevent obesity-related morbidity and mortality in adults: updated evidence report and systematic review for the US Preventive Services Task Force. JAMA 320:1172–1191
Lin HY, Huang CK, Tai CM, Lin HY, Kao YH, Tsai CC, Hsuan CF, Lee SL, Chi SC, Yen YC (2013) Psychiatric disorders of patients seeking obesity treatment. BMC Psychiatry 13:1
Linardon J, Brennan L, de la Piedad Garcia X (2016) Rapid response to eating disorder treatment: a systematic review and meta-analysis. Int J Eat Disord 49:905–919
Linardon J, Fairburn CG, Fitzsimmons-Craft EE, Wilfley DE, Brennan L (2017) The empirical status of the third-wave behaviour therapies for the treatment of eating disorders: a systematic review. Clin Psychol Rev 58:125–140
Lowe CJ, Reichelt AC, Hall PA (2019) The prefrontal cortex and obesity: a health neuroscience perspective. Trends Cogn Sci 23:349–361
Mensink GB, Schienkiewitz A, Haftenberger M, Lampert T, Ziese T, Scheidt-Nave C (2013) Übergewicht und Adipositas in Deutschland. Bundesgesundheitsblatt 56:786–794
Palavras MA, Hay P, Mannan H, da Luz FQ, Sainsbury A, Touyz S, Claudino AM (2020) Integrated weight loss and cognitive behavioural therapy (CBT) for the treatment of recurrent binge eating and high body mass index: a randomized controlled trial. Eat Weight Disord. https://doi.org/10.1007/s40519-020-00846-2
Raman J, Hay P, Tchanturia K, Smith E (2018) A randomised controlled trial of manualized cognitive remediation therapy in adult obesity. Appetite 123:269–279
Schag K, Rennhak SK, Leehr EJ, Skoda EM, Becker S, Bethge W, Martus P, Zipfel S, Giel KE (2019) IMPULS: Impulsivity-focused group intervention to reduce binge eating episodes in patients with binge eating disorder—a randomised controlled trial. Psychother Psychosom 88:141–153
Stice E, Gau JM, Rohde P, Shaw H (2017) Risk factors that predict future onset of each DSM‑5 eating disorder: predictive specificity in high-risk adolescent females. J Abnorm Psychol 126:38–51
Stubbs J, Whybrow S, Teixeira P, Blundell J, Lawton C, Westenhoefer J, Engel D, Shepherd R, McConnon A, Gilbert P, Raats M (2011) Problems in identifying predictors and correlates of weight loss and maintenance: implications for weight control therapies based on behaviour change. Obes Rev 12:688–708
Tanofsky-Kraff M, Shomaker LB, Olsen C, Roza CA, Wolkoff LE, Columbo KM, Raciti G, Zocca JM, Wilfley DE, Yanovski SZ, Yanovski JA (2011) A prospective study of pediatric loss of control eating and psychological outcomes. J Abnorm Psychol 120:108–118
Teixeira PJ, Carraça EV, Marques MM, Rutter H, Oppert JM, De Bourdeaudhuij I, Lakerveld J, Brug J (2015) Successful behavior change in obesity interventions in adults: a systematic review of self-regulation mediators. BMC Med 13:84
Udo T, Grilo CM (2018) Prevalence and correlates of DSM-5-defined eating disorders in a nationally representative sample of U.S. adults. Biol Psychiatry 84:345–354
Udo T, Grilo CM (2019) Psychiatric and medical correlates of DSM‑5 eating disorders in a nationally representative sample of adults in the United States. Int J Eat Disord 52:42–50
Udo T, Grilo CM (2020) Physical activity levels and correlates in nationally representative sample of U.S. adults with healthy weight, obesity, and binge-eating disorder. Int J Eat Disord 53:85–95
Varkevisser RDM, Van Straalen MM, Kroeze W, Ket JCF, Steenhuis IHM (2019) Determinants of weight loss maintenance: a systematic review. Obes Rev 20:171–211
Walsh BT (2011) The importance of eating behavior in eating disorders. Physiol Behav 104:525–552
Wing RR, Phelan S (2005) Long-term weight loss maintenance. Am J Clin Nutr 82:222–225
Wonderlich SA, Gordon KH, Mitchell JE, Crosby RD, Engel SG (2009) The validity and clinical utility of binge eating disorder. Int J Eat Disord 42:687–705
Yang Y, Shields GS, Guo C, Liu Y (2018) Executive function performance in obesity and overweight individuals: a meta-analysis and review. Neurosci Biobehav Rev 84:225–244
de Zwaan M, Herpertz S, Zipfel S, Svaldi J, Friederich HC, Schmidt F, Mayr A, Lam T, Schade-Brittinger C, Hilbert A (2017) Effect of Internet-based guided self-help vs individual face-to-face treatment on full or subsyndromal binge eating disorder in overweight or bese patients: the INTERBED randomized clinical trial. JAMA Psychiatry 74:987–995
Ágh T, Kovács G, Supina D, Pawaskar M, Herman BK, Vokó Z, Sheehan DV (2016) A systematic review of the health-related quality of life and economic burdens of anorexia nervosa, bulimia nervosa, and binge eating disorder. Eat Weight Disord 21:353–364
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Interessenkonflikt
A. Hilbert gibt an, dass kein Interessenkonflikt besteht.
Für diesen Beitrag wurden von der Autorin keine Studien an Menschen oder Tieren durchgeführt. Für die aufgeführten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.
Rights and permissions
About this article
Cite this article
Hilbert, A. Adipositas und psychische Komorbidität: therapeutische Implikationen. Psychotherapeut 66, 10–15 (2021). https://doi.org/10.1007/s00278-020-00480-4
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00278-020-00480-4
Schlüsselwörter
- Binge-Eating-Störung
- Gewichtsreduktion
- Kognitive Verhaltenstherapie
- Adipositasmanagement
- Experimentelle Therapieforschung