Abstract
Myelodysplastic syndromes are usually associated with pancytopenia. Disorders involving deletion of the long arm of chromosome 5 (5q- syndrome) and, rarely, patients with karyotypic abnormalities involving chromosome 3 associated with abnormal thrombopoiesis may have a normal or even raised platelet count. Other cytogenetic abnormalities in myelodysplasia are invariably associated with cytopenia in one or all cell lineages. We report a patient who initially presented with slight anemia and a raised platelet count. Further investigations suggested a diagnosis of primary acquired sideroblastic anemia. Cytogenetic examination revealed a clone with trisomy 8. We believe this is the first reported case of trisomy 8 with trilineage myelodysplasia and thrombocytosis with primary acquired sideroblastic anemia.
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Received: 13 August 1996 /Accepted: 12 December 1996
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Patel, K., Kelsey, P. Primary acquired sideroblastic anemia, thrombocytosis, and trisomy 8. Ann Hematol 74, 199–201 (1997). https://doi.org/10.1007/s002770050283
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DOI: https://doi.org/10.1007/s002770050283