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Clostridium septicum sepsis and neutropenic enterocolitis in a patient treated with intensive chemotherapy for acute myeloid leukemia

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Abstract

 We report a case of neutropenic enterocolitis complicated by Clostridium septicum sepsis following intensive chemotherapy to induce remission of acute myeloid leukemia. With the trend towards more intensive chemotherapy, particularly using regimens that induce gastrointestinal toxicity, it is important to recognize the circumstances under which sepsis due to C. septicum is likely to occur, so that appropriate treatment can be instituted promptly.

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Authors and Affiliations

  1. Department of International Medicine, St. Radboud University Hospital, P. O. Box 9101, NL-6500 HB Nijmegen, The Netherlands, , , , , , NL

    M. J. M. Pouwels

  2. Department of Hematology, St. Radboud University Hospital, Nijmegen, The Netherlands, , , , , , NL

    J. P. Donnelly, J. M. M. Raemaekers & B. E. de Pauw

  3. Department of Medical Microbiology, St. Radboud University Hospital, Nijmegen, The Netherlands, , , , , , NL

    P. E. Verweij

Authors
  1. M. J. M. Pouwels
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  2. J. P. Donnelly
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  3. J. M. M. Raemaekers
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  4. P. E. Verweij
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  5. B. E. de Pauw
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Received: 20 November 1996 / Accepted: 19 December 1996

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Pouwels, M., Donnelly, J., Raemaekers, J. et al. Clostridium septicum sepsis and neutropenic enterocolitis in a patient treated with intensive chemotherapy for acute myeloid leukemia. Ann Hematol 74, 143–147 (1997). https://doi.org/10.1007/s002770050273

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  • DOI: https://doi.org/10.1007/s002770050273

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