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Allogeneic transplantation of blood stem cells: Coming of age?

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Abstract

Mobilized peripheral blood progenitor cells (PBSC) are increasingly being used instead of bone marrow for allogeneic transplantation. The purpose of the present article is to give a concise and clinically oriented overview on current results and perspectives of allogeneic peripheral blood stem cell transplantation, with particular focus on reconstitution of hematopoiesis and the immune system, graft-versus-host disease, graft-versus-leukemia effects, intensity-reduced conditioning, and graft engineering.

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Authors and Affiliations

  1. Second Department of Medicine, University of Kiel, Chemnitzstrasse 33, 24116 Kiel, Germany

    Peter Dreger & Norbert Schmitz

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  1. Peter Dreger
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  2. Norbert Schmitz
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Dreger, P., Schmitz, N. Allogeneic transplantation of blood stem cells: Coming of age?. Ann Hematol 80, 127–136 (2001). https://doi.org/10.1007/s002770000279

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  • DOI: https://doi.org/10.1007/s002770000279

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