Skip to main content
Log in

Leukemic non-nodal cyclin D1- and SOX11-negative mantle cell lymphoma with CCND3::IGH rearrangement

  • Letter to the Editor
  • Published:
Annals of Hematology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

References

  1. Alaggio R, Amador C, Anagnostopoulos I, Attygalle AD, Araujo IBO, Berti E, Bhagat G, Borges AM, Boyer D, Calaminici M, Chadburn A, Chan JKC, Cheuk W, Chng WJ, Choi JK, Chuang SS, Coupland SE, Czader M, Dave SS, de Jong D, Du MQ, Elenitoba-Johnson KS, Ferry J, Geyer J, Gratzinger D, Guitart J, Gujral S, Harris M, Harrison CJ, Hartmann S, Hochhaus A, Jansen PM, Karube K, Kempf W, Khoury J, Kimura H, Klapper W, Kovach AE, Kumar S, Lazar AJ, Lazzi S, Leoncini L, Leung N, Leventaki V, Li XQ, Lim MS, Liu WP, Louissaint A Jr, Marcogliese A, Medeiros LJ, Michal M, Miranda RN, Mitteldorf C, Montes-Moreno S, Morice W, Nardi V, Naresh KN, Natkunam Y, Ng SB, Oschlies I, Ott G, Parrens M, Pulitzer M, Rajkumar SV, Rawstron AC, Rech K, Rosenwald A, Said J, Sarkozy C, Sayed S, Saygin C, Schuh A, Sewell W, Siebert R, Sohani AR, Tooze R, Traverse-Glehen A, Vega F, Vergier B, Wechalekar AD, Wood B, Xerri L, Xiao W (2022) The 5th edition of the world health organization classification of haematolymphoid tumours: lymphoid neoplasms. Leukemia 36(7):1720–1748. https://doi.org/10.1038/s41375-022-01620-2

  2. Royo C et al (2012) Non-nodal type of mantle cell lymphoma is a specific biological and clinical subgroup of the disease. Leukemia 26(8):1895–1898

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Xu J et al (2019) SOX11-negative mantle cell lymphoma: clinicopathologic and prognostic features of 75 patients. Am J Surg Pathol 43(5):710–716

    Article  PubMed  Google Scholar 

  4. Salaverria I et al (2013) CCND2 rearrangements are the most frequent genetic events in cyclin D1(-) mantle cell lymphoma. Blood 121(8):1394–1402

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Martín-Garcia D et al (2019) CCND2 and CCND3 hijack immunoglobulin light-chain enhancers in cyclin D1(-) mantle cell lymphoma. Blood 133(9):940–951

    Article  PubMed  PubMed Central  Google Scholar 

  6. Mozos A et al (2009) SOX11 expression is highly specific for mantle cell lymphoma and identifies the cyclin D1-negative subtype. Haematologica 94(11):1555–1562

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. Zhao Y et al (2022) Chronic lymphocytic leukemia with t(6;14) (p21;q32) CCND3-IGH: CCND3 rearrangement does not necessarily define a cyclin D1-negative mantle cell lymphoma. Hematol Oncol 40(1):111–114

    Article  PubMed  Google Scholar 

  8. Sonoki T et al (2001) Cyclin D3 is a target gene of t(6;14)(p21.1;q32.3) of mature B-cell malignancies. Blood 98(9):2837–2844

    Article  CAS  PubMed  Google Scholar 

  9. Nadeu F et al (2022) Detection of early seeding of Richter transformation in chronic lymphocytic leukemia. Nat Med 28(8):1662–1671

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Contributions

L. T. made the initial diagnosis and edited the manuscript.

J. Y. made the initial diagnosis.

G. B. managed/treated the patient and edited the manuscript and also obtained verbal patient consent.

C. CS. Y. made the diagnosis and edited the manuscript.

B. J. D. interpreted the FISH assay and edited the manuscript.

E. K. performed and interpreted the next-generation sequencing assay and edited the manuscript.

D. W. interpreted the flow cytometry and next-generation sequencing data and edited the manuscript.

K. N. N. wrote the manuscript, made the diagnosis, and edited the manuscript.

Corresponding author

Correspondence to Kikkeri N Naresh.

Ethics declarations

Ethics approval

The University of Washington has informed us that IRB review and approval are not required for publishing a case report.

Consent to participate

The patient’s permission and HIPAA authorization were obtained. Dr. Goldy Bansal obtained verbal patient consent.

Conflict of interest

The authors declare no competing interests.

Additional information

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Tan, L., Bansal, G., Yeung, C.C. et al. Leukemic non-nodal cyclin D1- and SOX11-negative mantle cell lymphoma with CCND3::IGH rearrangement. Ann Hematol 103, 667–669 (2024). https://doi.org/10.1007/s00277-023-05514-w

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00277-023-05514-w

Navigation