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Data are available per reasonable request from the corresponding author.
References
Acute myeloid leukemia [AML] in adults 2023 [Available from: https://www.cancer.org/cancer/types/acute-myeloid-leukemia.html
Newell LF, Cook RJ (2021) Advances in acute myeloid leukemia. BMJ [Clin Res ed] 375:n2026
Zeidan AM, Podoltsev NA, Wang X, Zhang C, Bewersdorf JP, Shallis RM et al (2020) Patterns of care and clinical outcomes with cytarabine-anthracycline induction chemotherapy for AML patients in the United States. Blood Adv 4(8):1615–1623
HCUP National Inpatient Sample [NIS]. Healthcare cost and utilization project [HCUP]. 2016, 2017, 2018, 2019, 2020. Agency for Healthcare Research and Quality, Rockville, MD. 2022 [Available from: https://www.hcup-us.ahrq.gov/nisoverview.jsp
Cram P, Hillis SL, Barnett M, Rosenthal GE (2004) Effects of weekend admission and hospital teaching status on in-hospital mortality. Am J Med 117(3):151–157
Mohammad Ammad U, Din HS, Shahzad M, Liaqat H, Sweet K (2023) The impact of mild-to-moderate chronic kidney disease on hospitalization outcomes in patients with acute myeloid leukemia. Leukem Lympho 64(5):1040–1044. https://doi.org/10.1080/10428194.2023.2190435
Tawfik B, Pardee TS, Isom S, Sliesoraitis S, Winter A, Lawrence J, Powell BL, Klepin HD (2016) Comorbidity, age, and mortality among adults treated intensively for acute myeloid leukemia (AML). J Geriatr Oncol 7(1):24–31. https://doi.org/10.1016/j.jgo.2015.10.182
Ali NA, O'Brien JM Jr, Blum W, Byrd JC, Klisovic RB, Marcucci G, Phillips G, Marsh CB, Lemeshow S, Grever MR (2007) Hyperglycemia in patients with acute myeloid leukemia is associated with increased hospital mortality. Cancer 110:96–102. https://doi.org/10.1002/cncr.22777
Ballo O, Eladly F, Büttner S, Stratmann JA, Rudolf S, Brunnberg U et al (2021) Acute kidney injury adversely affects the clinical course of acute myeloid leukemia patients undergoing induction chemotherapy. Ann Hematol 100(5):1159–1167
Petrone G, Handa S, Gupta K, Khan A, Rajeeve S (2019) Acute myeloid leukemia and cirrhosis: trends in utilization of induction chemotherapy, rate of hospitalizations and mortality. Blood. 134(Supplement_1):3864
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All authors contributed to the study’s conception and design. Material preparation, data collection, and analysis were performed by KR. The first draft of the manuscript was written by SS and SSC. All authors commented on previous versions of the manuscript. SS performed project supervision. All authors made significant contributions to writing the manuscript and read and approved the final manuscript.
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National Inpatient Sample data is released in a de-identified form by the Healthcare Cost and Utilization Project (HCUP0. The provider further waives users of all ethical and IRB approvals. Additional information can be found at https://hcup-us.ahrq.gov/nisoverview.jsp.The study was performed in accordance with the ethical standards as laid down in the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards.
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Savani, S., Chennapragada, S.S., Ramphul, K. et al. Factors associated with inpatient mortality during daunorubicin and cytarabine induction in adults with acute myeloid leukemia—a national inpatient sample analysis. Ann Hematol 103, 663–665 (2024). https://doi.org/10.1007/s00277-023-05505-x
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DOI: https://doi.org/10.1007/s00277-023-05505-x