Skip to main content

Advertisement

Log in

Hemophagocytosis by multinucleated leukemic blasts, basophilia, and micromegakaryocytes in AML with TLS::ERG

  • Letter to the Editor
  • Published:
Annals of Hematology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

References

  1. Hastings A, Apperley JF, Nadal-Melsio E, Brown L, Bain BJ (2021) Acute myeloid leukemia with a severe coagulopathy and t(8;16)(p11;p13). Am J Hematol 96(1):163–164

    Article  PubMed  Google Scholar 

  2. Coulthard S, Chase A, Orchard K et al (1998) Two cases of inv(8)(p11q13) in AML with erythrophagocytosis: a new cytogenetic variant. Br J Haematol 100(3):561–563

    Article  CAS  PubMed  Google Scholar 

  3. Park JE, Park IJ, Lim YA, Lee WG, Cho SR (2013) Hemophagocytosis by leukemic blasts in B lymphoblastic leukemia with t(12;21)(p13;q22); TEL-AML1 (ETV6-RUNX1): a case report. Ann Clin Lab Sci 43(2):186–189

    PubMed  Google Scholar 

  4. Li T, Ma C, Li X et al (2023) Blasts with inclusions, filamentous projections and erythrophagocytosis in a patient with a myelodysplastic syndrome. Br J Haematol 200(2):122

    Article  CAS  PubMed  Google Scholar 

  5. Chi Y, Lindgren V, Quigley S, Gaitonde S (2008) Acute myelogenous leukemia with t(6;9)(p23;q34) and marrow basophilia: an overview. Arch Pathol Lab Med 132(11):1835–1837

    Article  PubMed  Google Scholar 

  6. Khoury JD, Solary E, Abla O et al (2022) The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: myeloid and histiocytic/dendritic neoplasms. Leuk 36(7):1703–1719

    Article  Google Scholar 

  7. Henter JI, Horne A, Arico M et al (2007) HLH-2004: diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis. Pediatr Blood Cancer 48(2):124–131

    Article  PubMed  Google Scholar 

  8. Jekarl DW, Kim M, Lim J et al (2010) CD56 antigen expression and hemophagocytosis of leukemic cells in acute myeloid leukemia with t(16;21)(p11;q22). Int J Hematol 92(2):306–313

    Article  CAS  PubMed  Google Scholar 

  9. Kanazawa T, Ogawa C, Taketani T et al (2005) TLS/FUS-ERG fusion gene in acute lymphoblastic leukemia with t(16;21)(p11;q22) and monitoring of minimal residual disease. Leuk Lymphoma 46(12):1833–1835

    Article  CAS  PubMed  Google Scholar 

  10. Zhang H, Zhan Q, Wang X et al (2022) TLS/FUS-ERG fusion gene in acute leukemia and myelodysplastic syndrome evolved to acute leukemia: report of six cases and a literature review. Ann Hematol 101(12):2583–2600

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Contributions

All authors contributed to the paper conception and design. Clinical and histological data were collected by Fang Long, Xingqin Huang, and Yun Zhang. The draft of the manuscript was written by Ting Li and Xiaopeng Gao, and all authors read and approved the final manuscript.

Corresponding author

Correspondence to Fang Long.

Ethics declarations

Ethical approval

All procedures performed in the study involving human participants were in accordance with the ethical standards of the institutional and national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Conflict of interest

The authors declare no competing interests.

Informed consent

Informed consent was obtained from this patient.

Additional information

Publisher’s note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Huang, X., Li, T., Zhang, Y. et al. Hemophagocytosis by multinucleated leukemic blasts, basophilia, and micromegakaryocytes in AML with TLS::ERG. Ann Hematol 102, 3279–3281 (2023). https://doi.org/10.1007/s00277-023-05382-4

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00277-023-05382-4

Navigation