References
Alsultan A, Shamseldin HE, Osman ME et al (2013) MYSM1 is mutated in a family with transient transfusion-dependent anemia, mild thrombocytopenia, and low NK-and B-cell counts. Blood 122(23):3844–3845
Bahrami E, Witzel M, Racek T et al (2017) MYSM1 deficiency – genotoxic stress-associated bone marrow failure and developmental aberrations. J Allergy Clin Immunol 140(4):1112–1119
Le Guen T, Touzot F, Andre-Schmutz I et al (2015) An in vivo genetic reversion highlights the crucial role of Myb-like, SWIRM, and MPN domain 1 (MYSM1) in human hematopoiesis and lymphocyte differentiation. J Allergy Clin Immunol 136(6):1619–1626
Nijnik A, Clare S, Hale C et al (2012) The critical role of histone H2A-deubiquitinase Mysm1 in hematopoiesis and lymphocyte differentiation. Blood 119(6):1370–1379
Barhoom D, Mohseni R, Behfar M et al (2021) Successful allogeneic stem cell transplantation with fludarabine-based reduced intensity conditioning in bone marrow failure syndrome 4. Pediatr Transplant 25(7):e14089
Acknowledgements
I would like to thank the patient and his family.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Research involving human participants and/or animals
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
Informed consent
Informed consent was obtained from the patient/participant included in the study.
Competing interests
The author declares he no competing interests.
Additional information
Publisher's note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Hashem, H. Hematopoietic cell transplantation for MYSM1 deficiency: not so much an easy task. Ann Hematol 101, 2543–2544 (2022). https://doi.org/10.1007/s00277-022-04937-1
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00277-022-04937-1