Skip to main content
SpringerLink
Log in

Subclonal acquisition of a BCR::ABL1 fusion in a chronic myelomonocytic leukemia

  • Letter to the Editor
  • Published:
Annals of Hematology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

References

  1. Gabert J, Beillard E, van der Velden VHJ et al (2003) Standardization and quality control studies of ‘real-time’ quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia – a Europe Against Cancer Program. Leukemia 17:2318–2357. https://doi.org/10.1038/sj.leu.2403135

    Article  CAS  PubMed  Google Scholar 

  2. Coltro G, Mangaonkar AA, Lasho TL et al (2020) Clinical, molecular, and prognostic correlates of number, type, and functional localization of TET2 mutations in chronic myelomonocytic leukemia (CMML)—a study of 1084 patients. Leukemia 34:1407–1421. https://doi.org/10.1038/s41375-019-0690-7

    Article  CAS  PubMed  Google Scholar 

  3. Arber DA, Orazi A, Hasserjian R et al (2016) The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia. Blood 127:2391–2405. https://doi.org/10.1182/blood-2016-03-643544

    Article  CAS  PubMed  Google Scholar 

  4. Chelapareddy LR, Sen S (2018) Philadelphia translocation in MDS: a case report and a brief review of the literature looking at its prevalence, disease progression, and treatment options. Case Rep Hematol 2018:1–6. https://doi.org/10.1155/2018/5865321

    Article  Google Scholar 

  5. Bacher U, Haferlach T, Alpermann T et al (2011) Subclones with the t(9;22)/BCR-ABL1 rearrangement occur in AML and seem to cooperate with distinct genetic alterations: subclones with the t(9;22)/BCR-ABL1 rearrangement. Br J Haematol 152:713–720. https://doi.org/10.1111/j.1365-2141.2010.08472.x

    Article  PubMed  Google Scholar 

  6. Wakayama T, Maniwa Y, Ago H et al (2001) A variant form of myelodysplastic syndrome with Ph− minor-BCR/ABL transcript. Int J Hematol 74:58–63. https://doi.org/10.1007/BF02982550

    Article  CAS  PubMed  Google Scholar 

  7. Roumier C, Daudignon A, Soenen V et al (1999) p190 bcr-abl rearrangement: a secondary cytogenetic event in some chronic myeloid disorders? 84:6

Download references

Author information

Authors and Affiliations

  1. Institute of Medical Genetics, Jeanne de Flandre Hospital, CHU Lille, Avenue Eugène Avinée, 59037, Lille Cedex, France

    Benjamin Podvin, Hélène Guermouche & Pauline Roynard

  2. Hematology Department, CHU Lille, F-59000, Lille, France

    Laure Goursaud & Céline Berthon

  3. Univ. Lille, CNRS, Inserm, CHU Lille, IRCL, UMR9020 – UMR1277 - Canther – Cancer Heterogeneity, Plasticity and Resistance to Therapies, F-59000, Lille, France

    Céline Berthon, Nicolas Duployez & Catherine Roche-Lestienne

  4. Laboratory of Hematology, CHU Lille, F-59000, Lille, France

    Mahdi Ouafi, Elise Fourner, Nicolas Duployez & Olivier Nibourel

Authors
  1. Benjamin Podvin
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Hélène Guermouche
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Pauline Roynard
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Laure Goursaud
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Céline Berthon
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Mahdi Ouafi
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Elise Fourner
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Nicolas Duployez
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Olivier Nibourel
    View author publications

    You can also search for this author in PubMed Google Scholar

  10. Catherine Roche-Lestienne
    View author publications

    You can also search for this author in PubMed Google Scholar

Contributions

ON, MO, EF, and BP performed morphological assays. ON, MO, EF, HG, PR, and BP performed genetics assays. LG and CB provided clinical data. BP, CRL, and HG wrote the manuscript which was approved by all authors.

Corresponding author

Correspondence to Benjamin Podvin.

Ethics declarations

Ethics approval

The study was conducted according to the Declaration of Helsinki and was approved by the Human Research Committee of Lille and the internal review board of the Lille University Hospital Tumor Bank (certification NF 96900-2014/65453-1).

Consent to participate

Informed consent was obtained from all individual participants included in the study.

Conflict of interest

The authors declare no competing interests.

Additional information

Publisher’s note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Podvin, B., Guermouche, H., Roynard, P. et al. Subclonal acquisition of a BCR::ABL1 fusion in a chronic myelomonocytic leukemia. Ann Hematol 101, 2093–2095 (2022). https://doi.org/10.1007/s00277-022-04861-4

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00277-022-04861-4

Search

Navigation