References
Laubach JP, Moslehi SAF, San Miguel JF et al (2017) A retrospective analysis of 3954 patients in phase 2/3 trials of bortezomib for treatment of multiple myeloma: towards providing a benchmark for cardiac safety profile of proteasome inhibition in multiple myeloma. Br J Haem 178(4):547–560. https://doi.org/10.1111/bjh.14708
Mikhael JR, Schuster SR, Jimenez-Zepeda VH, Bello N, Spong J, Reeder CB et al (2012) Cyclophosphamide-bortezomib-dexamethasone (CyBorD) produces rapid and complete hematologic response in patients with AL amyloidosis. Blood 119(19):4391–4394
Cole DC, Frishman WH (2018) Cardiovascular complications of proteasome inhibitors used in multiple myeloma. Cardiol Rev 26(3):122–129. https://doi.org/10.1097/CRD.0000000000000183
Meseeha MG, Kolade VO, Attia MN (2015) Partially reversible bortezomib-induced cardiotoxicity: an unusual cause of acute cardiomyopathy. J Community Hosp Intern Med Perspect 5(6):28982. https://doi.org/10.3402/jchimp.v5.28982
Bockorny M, Chakravarty S, Schulman P, Bockorny B, Bona R (2012) Severe heart failure after bortezomib treatment in a patient with multiple myeloma: a case report and review of the literature. Acta Haematol 128(4):244–247. https://doi.org/10.1159/000340050
Kumar SK, Gertz MA, Dispenzieri A (2019) Validation of Mayo Clinic Staging System for light chain amyloidosis with high-sensitivity troponin. J Clin Oncol 37(2):171–173
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This article does not contain any studies involving human participants and/or animals. This article is based on a case report involving a single patient; informed consent was obtained.
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FM received fees for lectures from GE Healthcare, Hamilton Medical, SEDA SpA, outside the present work. GT received fees for lectures from GE Healthcare, outside the present work.
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Valentino Dammassa and Alessandra Greco shared first authorship.
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Dammassa, V., Greco, A., Totaro, R. et al. Bortezomib-induced cardiogenic shock in a multiple myeloma patient with K light-chain cardiac amyloidosis. Ann Hematol 101, 2087–2088 (2022). https://doi.org/10.1007/s00277-022-04858-z
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DOI: https://doi.org/10.1007/s00277-022-04858-z