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A rare de novo pure erythroid leukemia with JAK2 R683S mutation

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References

  1. Santos FP, Bueso-Ramos CE, Ravandi F (2010) Acute erythroleukemia: diagnosis and management. Expert Rev Hematol 3:705–718. https://doi.org/10.1586/ehm.10.62

    Article  PubMed  Google Scholar 

  2. Wang SA, Hasserjian RP (2012) Erythroid proliferations in myeloid neoplasms. Hum Pathol 43:153–164. https://doi.org/10.1016/j.humpath.2011.08.008

    Article  CAS  PubMed  Google Scholar 

  3. Swerdlow SH, Campo E, Harris NL et al (2008) WHO classification of tumors of haematopoietic and lymphoid tissues. International Agency for Research on Cancer, Lyon

    Google Scholar 

  4. Wang SA, Hasserjian RP (2015) Acute erythroleukemias, acute megakaryoblastic leukemias, and reactive mimics: a guide to a number of perplexing entities. Am J Clin Pathol 144:44–60

    Article  CAS  Google Scholar 

  5. Wang W, Wang SA, Jeffrey Medeiros L, Khoury JD (2017) Pure erythroid leukemia. Am J Hematol 92:292–296. https://doi.org/10.1002/ajh.24626

    Article  PubMed  Google Scholar 

  6. Wang RQ, Gao XN, Yu L (2019) The prognostic impact of tet oncogene family member 2 mutations in patients with acute myeloid leukemia: a systematic review and meta-analysis. BMC Cancer 19:389–400. https://doi.org/10.1186/s12885-019-5602-8

    Article  PubMed  PubMed Central  Google Scholar 

  7. Li F, Guo HY, Wang M et al (2013) The effects of R683S (G) genetic mutations on the JAK2 activity, structure and stability. Int J Biol Macromol 60:186–195

    Article  Google Scholar 

  8. Bercovich D, Ganmore I, Scott LM et al (2008) Mutations of JAK2 in acute lymphoblastic leukaemias associated with Down’s syndrome. Lancet 372:1484–1492

    Article  CAS  Google Scholar 

  9. Wu QY, Guo HY, Li F et al (2013) Disruption of E627 and R683 interaction is responsible for B-cell acute lymphoblastic leukemia caused by JAK2 R683G(S) mutations. Leuk Lymphoma 54:2693–2670

    Article  CAS  Google Scholar 

  10. Bank A, Larsen PR, Anderson HM (1966) Di Guglielmo’s syndrome after polycythemia. N Engl J Med 275:489–490. https://doi.org/10.1056/NEJM196609012750908

    Article  CAS  PubMed  Google Scholar 

  11. Brada SJ, de Wolf JT, Poppema S et al (1998) Ischaemic colitis and lung infiltrates caused by extramedullary haematopoiesis in a patient with an acute erythroid leukaemia following polycythaemia vera. Neth J Med 52:142–146

    Article  CAS  Google Scholar 

  12. Li H, Hasserjian RP, Kroft SH et al (2016) Pure erythroid leukemia and erythroblastic sarcoma evolving from chronic myeloid neoplasms. Am J Clin Pathol 145:538–551. https://doi.org/10.1093/ajcp/aqw033

    Article  CAS  PubMed  Google Scholar 

  13. Santos FP, Faderl S, Garcia-Manero G et al (2009) Adult erythroleukemia: an analysis of 91 patients treated at a single institution. Leukemia 23:2275–2280. https://doi.org/10.1038/leu.2009.181

    Article  CAS  PubMed  PubMed Central  Google Scholar 

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Authors and Affiliations

Authors

Contributions

Ms. Rebecca Z Xu wrote the initial manuscript. Dr. Aly Karsan was responsible for the molecular diagnosis of disease. Dr. Zhaodong Xu was involved in the pathological diagnosis, modified the manuscript, and was responsible for the pathological images. Dr. Brian R Berry made the pathological diagnosis of pure erythroid leukemia and was the senior corresponding author.

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Correspondence to Zhaodong Xu or Brian R. Berry.

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The authors declare no competing interests.

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Brian R. Berry is senior corresponding author.

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Xu, R.Z., Karsan, A., Xu, Z. et al. A rare de novo pure erythroid leukemia with JAK2 R683S mutation. Ann Hematol 101, 921–922 (2022). https://doi.org/10.1007/s00277-021-04657-y

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  • DOI: https://doi.org/10.1007/s00277-021-04657-y

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