Skip to main content

Advertisement

Log in

Pyoderma gangrenosum: a too often overlooked facultative paraneoplastic disease

  • Letter to the Editor
  • Published:
Annals of Hematology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Al Ghazal P, Herberger K, Schaller J, Strölin A, Hoff NP, Goerge T, Roth H, Rabe E, Karrer S, Renner R, Maschke J, Horn T, Hepp J, Eming S, Wollina U, Zutt M, Sick I, Splieth B, Dill D, Klode J, Dissemond J (2013) Associated factors and comorbidities in patients with pyoderma gangrenosum in Germany: a retrospective multicentric analysis in 259 patients. Orphanet J Rare Dis 8:136

    Article  PubMed  PubMed Central  Google Scholar 

  2. Langan SM, Groves RW, Card TR, Gulliford MC (2012) Incidence, mortality, and disease associations of pyoderma gangrenosum in the United Kingdom: a retrospective cohort study. J Investig Dermatol 132(9):2166–2170

    Article  CAS  PubMed  Google Scholar 

  3. Kridin K, Cohen AD, Amber KT (2018) Underlying systemic diseases in pyoderma gangrenosum: a systematic review and meta-analysis. Am J Clin Dermatol 19:479–487

    Article  PubMed  Google Scholar 

  4. Schmidt H, Bostholt L, Geertsen P, Christensen IJ, Larsen S, Gehl J, von der Masse H (2005) Elevated neutrophil and monocyte counts in peripheral blood are associated with poor survival in patients with metastatic melanoma: a prognostic model. Br J Cancer 93:273–278

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. McGary CT, Miele ME, Welch DR (1995) Highly metastatic 13762NF rat mammary adenocarcinoma cell clones stimulate bone marrow by secretion of granulocyte-macrophage colony-stimulating factor/interleukin-3 activity. Am J Pathol 147:1668–1681

    CAS  PubMed  PubMed Central  Google Scholar 

  6. Lewis AM, Varghese S, Xu H, Alexander HR (2006) Interleukin-1 and cancer progression: the emerging role of interleukin-1 receptor antagonist as a novel therapeutic agent in cancer treatment. J Transl Med 4:48

    Article  PubMed  PubMed Central  Google Scholar 

  7. Ortega-Loayza AG, Nugent WH, Lucero OM, Washington SL, Nunley JR, Walsh SW (2018) Dysregulation of inflammatory gene expression in lesional and nonlesional skin of patients with pyoderma gangrenosum. Br J Dermatol 178(1):e35–e36

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Alex G. Ortega-Loayza.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

This article does not contain any studies with human participants or animals performed by any of the authors.

Additional information

Publisher’s note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Gupta, A.S., Ortega-Loayza, A.G. Pyoderma gangrenosum: a too often overlooked facultative paraneoplastic disease. Ann Hematol 98, 2247–2248 (2019). https://doi.org/10.1007/s00277-019-03732-9

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00277-019-03732-9

Navigation