Table 6 Incidence of NEs occurring in ≥ 2% of patients with or without prior NEs
Patients with events | Patients with prior NEs (n = 66) | Patients without prior NEs (n = 123) |
|---|---|---|
Any NE, n (%) | 43 (65) | 55 (45) |
Dizziness | 16 (24) | 10 (8) |
Tremor | 12 (18) | 21 (17) |
Confusional state | 10 (15) | 4 (3) |
Encephalopathy | 6 (9) | 4 (3) |
Ataxia | 6 (9) | 3 (2) |
Neurotoxicity | 4 (6) | 1 (1) |
Lethargy | 4 (6) | 1 (1) |
Convulsion | 4 (6) | 0 |
Aphasia | 3 (5) | 4 (3) |
Dysarthria | 3 (5) | 3 (2) |
Somnolence | 2 (3) | 7 (6) |
Paresthesia | 2 (3) | 5 (4) |
Disorientation | 2 (3) | 5 (4) |
Mental status changes | 2 (3) | 5 (4) |
Hypoesthesia | 2 (3) | 4 (3) |
Memory impairment | 2 (3) | 1 (1) |
Dysesthesia | 2 (3) | 1 (1) |
Delirium | 2 (3) | 0 |
Reflexes abnormal | 2 (3) | 0 |
Amnesia | 1 (2) | 1 (1) |
Depressed level of consciousness | 1 (2) | 0 |
Febrile delirium | 1 (2) | 0 |
Hemiparesis | 1 (2) | 1 (1) |
Hyperreflexia | 1 (2) | 1 (1) |
Facial nerve disorder | 1 (2) | 0 |
Leukoencephalopathy | 1 (2) | 0 |
Myoclonus | 1 (2) | 0 |
Postural dizziness | 1 (2) | 0 |
Restless legs syndrome | 1 (2) | 1 (1) |
Bradyphrenia | 0 | 2 (2) |
Nervous system disorder | 0 | 3 (2) |
Cognitive disorder | 0 | 3 (2) |
Nystagmus | 0 | 2 (2) |