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Splenic marginal zone lymphoma with a de novo t(8;14)(q24;q32) and a prolymphocytoid evolution responsive to rituximab-bendamustine

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Fig. 1

Abbreviations

SMZL:

splenic marginal zone lymphoma

NHL:

non-Hodgkin lymphoma

CD:

cluster of differentiation

MYC:

myelocytomatosis mutated

LDH:

lactate dehydrogenase

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Acknowledgements

We are grateful to the patient for the availability of the collection of the data; nurses and colleagues from the Division of Hematology at the Department of Medicine, Padua University Hospital (PUH). We thank Dr. E. Piva from the Clinical Pathology Division of the PUH for the precious collaboration in preparing the PB smears.

Funding

This work was made possible in part by the AIRC grant IG 18387 to FP.

Author information

Author notes

  1. Mitja Nabergoj

    Present address: Division of Hematology, Department of Oncology, Geneva University Hospitals, Geneva, Switzerland

Authors and Affiliations

  1. Hematology Unit, Department of Medicine - DIMED, University of Padova, Via Giustiniani, 2, Padova, Italy

    Greta Scapinello, Mitja Nabergoj, Andrea Visentin, Livio Trentin, Gianpietro Semenzato & Francesco Piazza

  2. Surgical Pathology and Cytopathology Unit, Department of Medicine - DIMED, University of Padova, Padova, Italy

    Marco Pizzi

  3. Radiology Unit, Department of Medicine - DIMED, University of Padova, Padova, Italy

    Stefania Vio

  4. Immunology and Molecular Oncology Unit, Veneto Institute of Oncology, IOV-IRCCS, Padova, Italy

    Annalisa Martines & Laura Bonaldi

  5. Laboratory of Normal and Malignant Hematopoiesis, Venetian Institute of Molecular Medicine, Via Orus 2, Padova, Italy

    Gianpietro Semenzato & Francesco Piazza

Authors
  1. Greta Scapinello
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  2. Marco Pizzi
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  3. Stefania Vio
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  4. Mitja Nabergoj
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  5. Andrea Visentin
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  6. Annalisa Martines
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  7. Laura Bonaldi
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  8. Livio Trentin
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  9. Gianpietro Semenzato
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  10. Francesco Piazza
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Contributions

GrS, MN, AV, LT, GS, and FP collected clinical data, supervised the work, and wrote the paper. SV performed the radiological analysis. MP performed the histological analysis. LB and AM performed the cytogenetic analysis.

Corresponding author

Correspondence to Francesco Piazza.

Ethics declarations

Declarations

The consent to publication of the material was previously obtained. The principles of the Declaration of Helsinki were followed. The Padua Region Ethic Committee approved the work (n. 4089/AO17). Data are available at the Department of Medicine, Padua University Hospital, Division of Hematology, Surgical Pathology, Radiology, and at the Istituto Oncologico Veneto (IOV), Division of Cytodiagnostics.

Conflict of interest

The authors declare that they have no conflict of interest.

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Scapinello, G., Pizzi, M., Vio, S. et al. Splenic marginal zone lymphoma with a de novo t(8;14)(q24;q32) and a prolymphocytoid evolution responsive to rituximab-bendamustine. Ann Hematol 97, 2001–2003 (2018). https://doi.org/10.1007/s00277-018-3351-4

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  • DOI: https://doi.org/10.1007/s00277-018-3351-4

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