Skip to main content
SpringerLink
Log in

Co-occurrence of type I CALR and two MPL mutations in patient with primary myelofibrosis

  • Letter to the Editor
  • Published:
Annals of Hematology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

References

  1. Tefferi A et al (2014) CALR vs JAK2 vs MPL-mutated or triple-negative myelofibrosis: clinical, cytogenetic and molecular comparisons. Leukemia 28(7):1472–1477

    Article  CAS  PubMed  Google Scholar 

  2. Lundberg P et al (2014) Clonal evolution and clinical correlates of somatic mutations in myeloproliferative neoplasms. Blood 123(14):2220–2228

    Article  CAS  PubMed  Google Scholar 

  3. McGaffin G et al (2014) JAK2 V617F and CALR mutations are not mutually exclusive; findings from retrospective analysis of a small patient cohort. Br J Haematol 2014 167(2):276–278

    CAS  Google Scholar 

  4. Gong JZ et al (2013) Laboratory practice guidelines for detecting and reporting JAK2 and MPL mutations in myeloproliferative neoplasms: a report of the Association for Molecular Pathology. J Mol Diagn 15(6):733–744

    Article  CAS  PubMed  Google Scholar 

  5. Usseglio F et al (2017) Detection of CALR and MPL mutations in low allelic burden JAK2 V617F essential thrombocythemia. J Mol Diagn 19(1):92–98

    Article  CAS  PubMed  Google Scholar 

  6. Pardanani A et al (2011) Primary myelofibrosis with or without mutant MPL: comparison of survival and clinical features involving 603 patients. Leukemia 25(12):1834–1839

    Article  CAS  PubMed  Google Scholar 

  7. Pardanani AD et al (2006) MPL515 mutations in myeloproliferative and other myeloid disorders: a study of 1182 patients. Blood 108(10):3472–3476

    Article  CAS  PubMed  Google Scholar 

  8. Klampfl T et al (2013) Somatic mutations of calreticulin in myeloproliferative neoplasms. N Engl J Med 369(25):2379–2390

    Article  CAS  PubMed  Google Scholar 

  9. Nangalia J et al (2013) Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2. N Engl J Med 369(25):2391–2405

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. Pietra D et al (2011) Deep sequencing reveals double mutations in cis of MPL exon 10 in myeloproliferative neoplasms. Haematologica 96(4):607–611

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  11. Rumi E et al (2014) Clinical effect of driver mutations of JAK2, CALR, or MPL in primary myelofibrosis. Blood 124(7):1062–1069

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Pathology and Laboratory Medicine, Case Western Reserve University School of Medicine, Cleveland, OH, USA

    Hammad Tashkandi, Erika M. Moore & Navid Sadri

  2. Department of Hematology and Oncology, Case Western Reserve University School of Medicine, Cleveland, OH, USA

    Benjamin Tomlinson & Teresa Goebel

  3. University Hospitals Cleveland Medical Center, 11100 Euclid Avenue, Cleveland, OH, 44106, USA

    Navid Sadri

Authors
  1. Hammad Tashkandi
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Erika M. Moore
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Benjamin Tomlinson
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Teresa Goebel
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Navid Sadri
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Navid Sadri.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Tashkandi, H., Moore, E.M., Tomlinson, B. et al. Co-occurrence of type I CALR and two MPL mutations in patient with primary myelofibrosis. Ann Hematol 96, 1417–1418 (2017). https://doi.org/10.1007/s00277-017-3022-x

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00277-017-3022-x

Keywords

Search

Navigation