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Hypoglycemia due to monoclonal anti-insulin antibody in a patient with multiple myeloma

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References

  1. Wasada T, Eguchi Y, Takayama S, Yao K, Hirata Y, Ishii S (1989) Insulin autoimmune syndrome associated with benign monoclonal gammopathy. Evidence for monoclonal insulin autoantibodies. Diabetes Care 12(2):147–150

    Article  CAS  PubMed  Google Scholar 

  2. Russell-Jones DL, Thomas SM, Simpson RD, Bevan PC, Bateman CJ (1990) The first reported case of hypoglycaemia as the presenting feature of invasive plasmacytoma with a paraprotein band and grossly elevated insulin levels. Br J Haematol 76(1):151–153

    Article  CAS  PubMed  Google Scholar 

  3. Redmon B, Pyzdrowski KL, Elson MK, Kay NE, Dalmasso AP, Nuttall FQ (1992) Hypoglycemia due to an insulin-binding monoclonal antibody in multiple myeloma. N Engl J Med 326(15):994–998

    Article  CAS  PubMed  Google Scholar 

  4. Arnqvist HJ, Halban PA, Mathiesen UL, Zahnd G, von Schenck SH (1993) Hypoglycaemia caused by atypical insulin antibodies in a patient with benign monoclonal gammopathy. J Intern Med 234(4):421–427

    Article  CAS  PubMed  Google Scholar 

  5. Khant M, Florkowski C, Livesey J, Elston M (2004) Insulin autoimmune syndrome due to IgG kappa paraprotein. Pathology 36(1):86–87

    Article  PubMed  Google Scholar 

  6. Halsall DJ, Mangi M, Soos M, Fahie-Wilson MN, Wark G, Mainwaring-Burton R, O’Rahilly S (2007) Hypoglycemia due to an insulin binding antibody in a patient with an IgA-kappa myeloma. J Clin Endocrinol Metab 92(6):2013–2016

    Article  CAS  PubMed  Google Scholar 

  7. Kasznicki J, Kosmalski M, Makarewicz J, Tarka J, Drzewoski J (2011) A case of recurrent, spontaneous postprandial and fasting hypoglycemia and insulin autoantibodies in a patient with coexisting Graves’ disease, megaloblastic anemia, and multiple myeloma. Diabet Dosw Klin 11(2):103–105

    Google Scholar 

  8. Waldron-Lynch F, Inzucchi SE, Menard L, Tai N, Preston-Hurlburt P, Hui P et al (2012) Relapsing and remitting severe hypoglycemia due to a monoclonal anti-insulin antibody heralding a case of multiple myeloma. J Clin Endocrinol Metab 97(12):4317–4323

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Lupsa BC, Chong AY, Cochran EK, Soos MA, Semple RK, Gorden P (2009) Autoimmune forms of hypoglycemia. Medicine (Baltimore) 88(3):141–153

    Article  CAS  Google Scholar 

  10. Decaux O, Laurat E, Perlat A, Cazalets C, Jego P, Grosbois B (2009) Systemic manifestations of monoclonal gammopathy. Eur J Intern Med 20(5):457–461

    Article  CAS  PubMed  Google Scholar 

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Correspondence to João Tadeu Damian Souto Filho.

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Souto Filho, J.T.D., Costa, M.F.F.D., de Abreu, G.A.R. et al. Hypoglycemia due to monoclonal anti-insulin antibody in a patient with multiple myeloma. Ann Hematol 95, 1363–1365 (2016). https://doi.org/10.1007/s00277-016-2702-2

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