References
Allen KJ, Gurrin LC, Constantine CC et al (2008) Iron-overload-related disease in HFE hereditary hemochromatosis. N Engl J Med 358:221–230. doi:10.1056/NEJMoa073286
Bacon BR, Britton RS (2008) Clinical penetrance of hereditary hemochromatosis. N Engl J Med 358:291–292. doi:10.1056/NEJMe078215
Rochette J, Le Gac G, Lassoued K et al (2010) Factors influencing disease phenotype and penetrance in HFE haemochromatosis. Hum Genet 128:233–248. doi:10.1007/s00439-010-0852-1
Scotet V, Mérour M-C, Mercier A-Y et al (2003) Hereditary hemochromatosis: effect of excessive alcohol consumption on disease expression in patients homozygous for the C282Y mutation. Am J Epidemiol 158:129–134. doi:10.1093/aje/kwg123
Moretti D, van Doorn GM, Swinkels DW, Melse-Boonstra A (2013) Relevance of dietary iron intake and bioavailability in the management of HFE hemochromatosis: a systematic review. Am J Clin Nutr 98:468–479. doi:10.3945/ajcn.112.048264
Aranda N, Viteri FE, Montserrat C, Arija V (2010) Effects of C282Y, H63D, and S65C HFE gene mutations, diet, and life-style factors on iron status in a general Mediterranean population from Tarragona, Spain. Ann Hematol 89:767–773. doi:10.1007/s00277-010-0901-9
EASL (2010) EASL clinical practice guidelines for HFE hemochromatosis. J Hepatol 53:3–22. doi:10.1016/j.jhep.2010.03.001
Bacon BR, Adams PC, Kowdley KV et al (2011) Diagnosis and management of hemochromatosis: 2011 Practice Guideline by the American Association for the Study of Liver Diseases. Hepatology 54:328–343. doi:10.1002/hep.24330
Adams PC, Barton JC (2010) How I treat hemochromatosis. Blood 116:317–325. doi:10.1182/blood-2010-01-261875
Nicolas G, Viatte L, Lou D-Q et al (2003) Constitutive hepcidin expression prevents iron overload in a mouse model of hemochromatosis. Nat Genet 34:97–101. doi:10.1038/ng1150
Author contributions
Philippe Saliou and Virginie Scotet did the concept and design, analysis and interpretation of data and drafting of the manuscript. Céline Tripogney and Brigitte Chanu did the inclusion of patients and acquisition of data. Isabelle Gourlaouen did the realisation of genetic testing. Marie-Christine Mérour did the entry and management of data. Gérald Le Gac and Jean-Baptiste Nousbaum did the critical revision of the manuscript for important intellectual content. Claude Férec did the study supervision
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The authors declare they have no conflict of interest.
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The study was approved by an ethics committee. Informed consent was obtained from all patients for being included in the study.
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Saliou, P., Le Gac, G., Mérour, MC. et al. HFE hemochromatosis: influence of dietary iron intake on the iron overload of C282Y homozygous patients. Ann Hematol 94, 1225–1227 (2015). https://doi.org/10.1007/s00277-015-2343-x
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DOI: https://doi.org/10.1007/s00277-015-2343-x