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A report on the co-occurrence of JAK2V617F and CALR mutations in myeloproliferative neoplasm patients

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References

  1. Tefferi A, Lasho TL, Finke CM et al (2014) CALR vs JAK2 vs MPL-mutated or triple-negative myelofibrosis: clinical, cytogenetic and molecular comparisons. Leukemia 28(7):1472–1477

    Article  CAS  PubMed  Google Scholar 

  2. McGaffin G, Harper K, Stirling D, et al. (2014) JAK2V617F and CALR mutations are not mutually exclusive; findings from retrospective analysis of a small patient cohort. Br J Haematol

  3. Lundberg P, Karow A, Nienhold R, Looser R, Hao-Shen H, Nissen I, Girsberger S, Lehmann T, Passweg J, Stern M, Beisel C, Kralovics R, Skoda RC (2014) Clonal evolution and clinical correlates of somatic mutations in myeloproliferative neoplasms. Blood 123(14):2220–2228

    Article  CAS  PubMed  Google Scholar 

  4. Nangalia J, Massie CE, Baxter EJ et al (2013) Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2. N Engl J Med 369:2391–2405

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  5. Klampfl T, Gisslinger H, Harutyunyan AS et al (2013) Somatic mutations of calreticulin in myeloproliferative neoplasms. N Engl J Med 369:2379–2390

    Article  CAS  PubMed  Google Scholar 

  6. Rotunno G, Mannarelli C, Guglielmelli P, Pacilli A, Pancrazzi A, Pieri L, Fanelli T, Bosi A, Vannucchi AM (2014) Impact of calreticulin mutations on clinical and hematological phenotype and outcome in essential thrombocythemia. Blood 123(10):1552–1555

    Article  CAS  PubMed  Google Scholar 

  7. Silver RT, Kiladjian JJ, Hasselbalch HC et al (2013) Interferon and the treatment of polycythemia vera, essential thrombocythemia and myelofibrosis. Expert Rev Hematol 6:49–58

    Article  CAS  PubMed  Google Scholar 

  8. Larsen TS, Møller MB, de Stricker K et al (2009) Minimal residual disease and normalization of the bone marrow after long-term treatment with alpha-interferon2b in polycythemia vera. A report on molecular response patterns in seven patients in sustained complete hematological remission. Hematology 14:331–334

    Article  CAS  PubMed  Google Scholar 

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Conflict of interest

The authors declare that they have no conflict of interest.

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Authors and Affiliations

  1. Department of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou Dadao North Street No. 1838, Guangzhou, 510515, People’s Republic of China

    Na Xu, Li Ding, Changxin Yin, Xuan Zhou, Lin Li, Yulin Li, Qisi Lu & Xiao-li Liu

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  1. Na Xu
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  2. Li Ding
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  3. Changxin Yin
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  4. Xuan Zhou
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  5. Lin Li
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  6. Yulin Li
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  7. Qisi Lu
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  8. Xiao-li Liu
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Corresponding author

Correspondence to Xiao-li Liu.

Additional information

Na Xu and Li Ding contributed equally to this study and should be considered as co-first authors.

This study was financially supported by the National Natural Science Foundation of China (No. 81170521).

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Xu, N., Ding, L., Yin, C. et al. A report on the co-occurrence of JAK2V617F and CALR mutations in myeloproliferative neoplasm patients. Ann Hematol 94, 865–867 (2015). https://doi.org/10.1007/s00277-014-2248-0

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  • DOI: https://doi.org/10.1007/s00277-014-2248-0

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