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Clinical efficacy of arsenic trioxide in a patient with acute promyelocytic leukemia with recurrent central nervous system involvement

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References

  1. Montesinos P, Dìaz-Mediavilla J, Debén G, Prates V, Tormo M, Rubio V, Pérez I, Fernàndez I, Viguria M, Rayòn C, Gonzàles J, de la Serna J, Esteve J, Bergua JM, Rivas C, Gonzàles M, Gonzàles JD, Negri S, Brunet S, Lowenberg B, Sanz M (2009) Central nervous system involvement at first relapse in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline monochemotherapy without intratecal prophylaxis. Haematologica 94(9):1242–1249

    Article  PubMed  CAS  Google Scholar 

  2. Sanz MA, Grimwade D, Tallman MS, Lowenberg B, Fenaux P, Estey EH, Naoe T, Lengfelder E, Buchner T, Dohner H, Burnett AK, Lo-Coco F (2009) Management of acute promyelocytic leukemia from an expert panel on behalf of the European leukemia net. Blood 113(9):1875–1891

    Article  PubMed  CAS  Google Scholar 

  3. Kiguchi T, Yoshino Y, Yuan B, Yoshizawa S, Kitahara T, Akahane D, Gotoh M, Kaise T, Toyoda H, Ohyashiki K (2009) Speciation of arsenic trioxide penetrates into cerebrospinal fluid in patients with acute promyelocytic leukemia. Leuk Res 34(3):403–405

    Article  PubMed  Google Scholar 

  4. Knipp S, Gattermann N, Schapira M, Käferstein H, Germing U (2007) Arsenic in the cerebrospinal fluid of a patient receiving arsenic trioxide for relapsed acute promyelocytic leukemia with CNS involvement. Leuk Res 31(11):1585–1587

    Article  PubMed  CAS  Google Scholar 

  5. Au WY, Tam S, Fong BM, Kwong YL (2008) Determinants of cerebrospinal fluid arsenic concentration in patients with acute promyelocytic leukemia on oral arsenic trioxide therapy. Blood 112(9):3587–3590

    Article  PubMed  CAS  Google Scholar 

  6. Kai T, Kimura H, Shiga Y, Ogawa K, Sato H, Maruyama Y (2006) Recurrent extramedullary relapse of acute promyelocytic leukemia after allogeneic stem cell transplantation: successful treatment by arsenic trioxide in combination with local radiotherapy. Int J Hematol 83(4):337–340

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Division of Hematology, Foundation IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy

    Patrizia Zappasodi, Marianna Rossi, Ilaria Ambaglio, Paolo Bernasconi, Alessandro Corso, Mario Lazzarino & Carlo Castagnola

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  1. Patrizia Zappasodi
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  2. Marianna Rossi
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  3. Ilaria Ambaglio
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  4. Paolo Bernasconi
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  6. Mario Lazzarino
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  7. Carlo Castagnola
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Correspondence to Patrizia Zappasodi.

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Zappasodi, P., Rossi, M., Ambaglio, I. et al. Clinical efficacy of arsenic trioxide in a patient with acute promyelocytic leukemia with recurrent central nervous system involvement. Ann Hematol 90, 595–597 (2011). https://doi.org/10.1007/s00277-010-1046-6

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  • DOI: https://doi.org/10.1007/s00277-010-1046-6

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