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Idiopathic neutropenia with fewer than 5% dysplasia may be a distinct entity of idiopathic cytopenia of undetermined significance

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References

  1. Brunning RD, Orazi A, Germing U, Le Beau MM, Porwit A, Vardiman JW et al (2008) Myelodysplastic syndromes. In: Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, Thiele J, Vardiman JW (eds) WHO classification of tumours of hematopoietic and lymphoid tissues. IARC, Lyon, pp 90–107

    Google Scholar 

  2. Wimazal F, Fonatsch C, Thalhammer R, Schwarzinger I, Müllauer L, Sperr WR et al (2007) Idiopathic cytopenia of undetermined significance (ICUS) versus low risk MDS: the diagnostic interface. Leuk Res 31:1461–1468

    Article  PubMed  Google Scholar 

  3. Mufti GJ, Bennett JM, Goasguen J, Bain BJ, Baumann I, Brunning R, International Working Group on Morphology of Myelodysplastic Syndrome et al (2008) Diagnosis and classification of myelodysplastic syndrome: International Working Group on Morphology of myelodysplastic syndrome (IWGM-MDS) consensus proposals for the definition and enumeration of myeloblasts and ring sideroblasts. Haematologica 93:1712–1717

    Article  PubMed  Google Scholar 

  4. Valent P, Horney H-P, Bennett JM, Fonatsch C, Germing U, Greenberg P et al (2007) Definitions and standards in the diagnosis and treatment of the myelodysplastic syndromes: consensus statements and report from a working conference. Leuk Res 31:727–736

    Article  PubMed  Google Scholar 

  5. Gupta R, Soupir CP, Johari V, Hasserjian RP (2007) Myelodysplastic syndrome with isolated deletion of chromosome 20q: an indolent disease with minimal morphological dysplasia and frequent thrombocytopenic presentation. Br J Haematol 139:265–288

    Article  PubMed  Google Scholar 

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Acknowledgments

Thanks are due to Professor J Patrick Barron, of the International Medical Communication Center of Tokyo Medical University, for his review of this manuscript. AK, TI, and KO performed hematologic examination, AK did cytogenetic study, and JHO reviewed the paper.

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None.

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Authors and Affiliations

  1. The First Department of Internal Medicine (Hematology Division), Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan

    Keiko Ando, Tamiko Iwabuchi & Kazuma Ohyashiki

  2. Division of Cytogenetics, Central Laboratory, Tokyo Medical University, Tokyo, Japan

    Atsushi Kodama

  3. Intractable Disease Research Center, Tokyo Medical University, Tokyo, Japan

    Junko H. Ohyashiki

Authors
  1. Keiko Ando
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  2. Atsushi Kodama
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  3. Tamiko Iwabuchi
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  4. Junko H. Ohyashiki
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  5. Kazuma Ohyashiki
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Corresponding author

Correspondence to Kazuma Ohyashiki.

Electronic supplementary materials

Below is the link to the electronic supplementary material.

File 1

Hematologic and clinical features in patients with <5% of dysplastic features of (DOC 29 kb)

File 2

Clinical and hematologic features in patients with unilineage dysplasia (DOC 30 kb)

File 3

Clinical and hematologic features in patients with multilineage dysplasia (DOC 33 kb)

File 4

Hematologic parameters of patients having fewer than 5% of marrow blasts classified by the WHO-2008 criteria (DOC 28 kb)

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Ando, K., Kodama, A., Iwabuchi, T. et al. Idiopathic neutropenia with fewer than 5% dysplasia may be a distinct entity of idiopathic cytopenia of undetermined significance. Ann Hematol 89, 733–735 (2010). https://doi.org/10.1007/s00277-009-0845-0

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  • DOI: https://doi.org/10.1007/s00277-009-0845-0

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