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Results of FLT3 mutation screening and correlations with immunophenotyping in 169 Brazilian patients with acute myeloid leukemia

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An Erratum to this article was published on 18 November 2009

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References

  1. Small D (2006) FLT3 mutations: biology and treatment. Hematology Am Soc Hematol Educ Program 178–184

  2. Auewarakul CU, Sritana N, Limwongse C, Thongnoppakhun W, Yenchitsomanus PT (2005) Mutations of the FLT3 gene in adult acute myeloid leukemia: determination of incidence and identification of a novel mutation in a Thai population. Cancer Genet Cytogenet 162(2):127–134

    Article  CAS  PubMed  Google Scholar 

  3. Bang SM, Ahn JY, Park J et al (2008) Low frequency and variability of FLT3 mutations in Korean patients with acute myeloid leukemia. J Korean Med Sci 23(5):833–837

    Article  CAS  PubMed  Google Scholar 

  4. Kiyoi H, Naoe T, Nakano Y et al (1999) Prognostic implication of FLT3 and N-RAS gene mutations in acute myeloid leukemia. Blood 93(9):3074–3080

    CAS  PubMed  Google Scholar 

  5. Jacomo RH, Melo RA, Souto FR et al (2007) Clinical features and outcomes of 134 Brazilians with acute promyelocytic leukemia who received ATRA and anthracyclines. Haematologica 92(10):1431–1432

    Article  PubMed  Google Scholar 

  6. Onsten T, Girardi FM, Coelho GM, Lima Frey MC, Paskulin G (2006) Cytogenetic and morphological findings in 166 patients with de novo acute myeloid leukemia in southern Brazil. Cancer Genet Cytogenet 170(2):167–170

    Article  CAS  PubMed  Google Scholar 

  7. Falini B, Nicoletti I, Martelli MF, Mecucci C (2007) Acute myeloid leukemia carrying cytoplasmic/mutated nucleophosmin (NPMc+ AML): biologic and clinical features. Blood 109(3):874–885

    Article  CAS  PubMed  Google Scholar 

  8. Grimwade D, Walker H, Oliver F et al (1998) The importance of diagnostic cytogenetics on outcome in AML: analysis of 1,612 patients entered into the MRC AML 10 trial. The Medical Research Council Adult and Children's Leukaemia Working Parties. Blood 92(7):2322–2333

    CAS  PubMed  Google Scholar 

  9. Armstrong SA, Kung AL, Mabon ME et al (2003) Inhibition of FLT3 in MLL. Validation of a therapeutic target identified by gene expression based classification. Cancer Cell 3(2):173–183

    Article  CAS  PubMed  Google Scholar 

  10. De Lourdes Chauffaille M, Borri D, Proto-Siqueira R, Moreira ES, Alberto FL (2008) Acute promyelocytic leukemia with t(15;17): frequency of additional clonal chromosome abnormalities and FLT3 mutations. Leuk Lymphoma 49(12):2387–2389

    Article  PubMed  Google Scholar 

  11. Emerenciano M, Menezes J, Vasquez ML, Zalcberg I, Thuler LC, Pombo-de-Oliveira MS (2008) Clinical relevance of FLT3 gene abnormalities in Brazilian patients with infant leukemia. Leuk Lymphoma 49(12):2291–2297

    Article  CAS  PubMed  Google Scholar 

  12. Vidriales MB, Orfao A, Gonzalez M et al (1993) Expression of NK and lymphoid-associated antigens in blast cells of acute myeloblastic leukemia. Leukemia 7(12):2026–2029

    CAS  PubMed  Google Scholar 

  13. Fagundes EM, Rocha V, Gloria AB et al (2006) De novo acute myeloid leukemia in adults younger than 60 years of age: socioeconomic aspects and treatment results in a Brazilian university center. Leuk Lymphoma 47(8):1557–1564

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Hematology Division, Department of Internal Medicine, National Institute of Science and Technology on Cell Based Therapy, Medical School of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil

    Antonio R. Lucena-Araujo, Danielle L. Souza, Fabio Morato de Oliveira, Mariana Tereza Lira Benicio, Lorena L. Figueiredo-Pontes, Barbara A. Santana-Lemos, Guilherme A. dos Santos, Rafael H. Jacomo & Eduardo M. Rego

  2. Department of Genetics, National Institute of Science and Technology on Cell Based Therapy, Medical School of Ribeirão Preto, University of São Paulo, Av. Bandeirantes, 3900, 14048-900, Ribeirão Preto, São Paulo, Brazil

    Anemari R. Dinarte-Santos & Wilson A. Silva-Jr

  3. Department of Hematology and Hemotherapy, Federal University of São Paulo, São Paulo, Brazil

    Mihoko Yamamoto & Maria de Lourdes Chauffaille

Authors
  1. Antonio R. Lucena-Araujo
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  2. Danielle L. Souza
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  3. Fabio Morato de Oliveira
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  4. Mariana Tereza Lira Benicio
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  5. Lorena L. Figueiredo-Pontes
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  7. Guilherme A. dos Santos
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  8. Rafael H. Jacomo
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  9. Anemari R. Dinarte-Santos
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  11. Wilson A. Silva-Jr
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  12. Maria de Lourdes Chauffaille
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  13. Eduardo M. Rego
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Corresponding author

Correspondence to Eduardo M. Rego.

Additional information

An erratum to this article can be found at http://dx.doi.org/10.1007/s00277-009-0860-1

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Lucena-Araujo, A.R., Souza, D.L., de Oliveira, F.M. et al. Results of FLT3 mutation screening and correlations with immunophenotyping in 169 Brazilian patients with acute myeloid leukemia. Ann Hematol 89, 225–228 (2010). https://doi.org/10.1007/s00277-009-0817-4

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  • DOI: https://doi.org/10.1007/s00277-009-0817-4

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