Annals of Hematology

, Volume 87, Issue 12, pp 1025–1026 | Cite as

Immature reticulocytes and its relevance to thrombosis

Letter to the Editor


  1. 1.
    Patel VP, Ciechanover A, Platt O, Lodish HF (1985) Mammalian reticulocytes lose adhesion to fibronectin during maturation to erythrocytes. Proc Natl Acad Sci USA 82:440–444 doi:10.1073/pnas.82.2.440 PubMedCrossRefGoogle Scholar
  2. 2.
    Brittain JE, Knoll CM, Ataga KI, Orringer EP, Parise LV (2008) Fibronectin bridges monocytes and reticulocytes via integrin alpha4beta1. Br J Haematol 141:872–881 doi:10.1111/j.1365-2141.2008.07056.x PubMedCrossRefGoogle Scholar
  3. 3.
    Koury MJ, Koury ST, Kopsombut P, Bondurant MC (2005) In vitro maturation of nascent reticulocytes to erythrocytes. Blood 105:2168–2174 doi:10.1182/blood-2004-2-616 PubMedCrossRefGoogle Scholar
  4. 4.
    Johnstone RM (1992) The Jeanne Manery-Fisher Memorial Lecture 1991: maturation of reticulocytes: formation of exosomes as a mechanism for shedding membrane proteins. Biochem Cell Biol 70:179–190PubMedCrossRefGoogle Scholar
  5. 5.
    Gasko O, Danon D (1972) Deterioration and disappearance of mitochondria during reticulocyte maturation. Exp Cell Res 75:159–169 doi:10.1016/0014-4827(72)90532-0 PubMedCrossRefGoogle Scholar
  6. 6.
    Ataga KI, Cappellini MD, Rachmilewitz EA (2007) Beta-thalassaemia and sickle cell anaemia as paradigms of hypercoagulability. Br J Haematol 139:3–13 doi:10.1111/j.1365-2141.2007.06740.x PubMedCrossRefGoogle Scholar
  7. 7.
    Cappellini MD, Grespi E, Cassinerio E, Bignamini D, Fiorelli G (2005) Coagulation and splenectomy: an overview. Ann N Y Acad Sci 1054:317–324 doi:10.1196/annals.1345.039 PubMedCrossRefGoogle Scholar
  8. 8.
    Stewart GW, Amess JA, Eber SW, Kingswood C, Lane PA, Smith BD, Mentzer WC (1996) Thromboembolic disease after splenectomy for hereditary stomatocytosis. Br J Haematol 93:303–310 doi:10.1046/j.1365-2141.1996.4881033.x PubMedCrossRefGoogle Scholar
  9. 9.
    Major A, Bauer C, Breymann C, Huch A, Huch R (1994) rh-erythropoietin stimulates immature reticulocyte release in man. Br J Haematol 87:605–608 doi:10.1111/j.1365-2141.1994.tb08320.x PubMedCrossRefGoogle Scholar
  10. 10.
    Gordeuk VR, Sergueeva AI, Miasnikova GY, Okhotin D, Voloshin Y, Choyke PL et al (2004) Congenital disorder of oxygen sensing: association of the homozygous Chuvash polycythemia VHL mutation with thrombosis and vascular abnormalities but not tumors. Blood 103:3924–3932 doi:10.1182/blood-2003–07–2535 PubMedCrossRefGoogle Scholar
  11. 11.
    Gordeuk VR, Prchal JT (2006) Vascular complications in Chuvash polycythemia. Semin Thromb Hemost 32:289–294 doi:10.1055/s-2006–939441 PubMedCrossRefGoogle Scholar
  12. 12.
    Brun A, Gaudernack G, Sandberg S (1990) A new method for isolation of reticulocytes: positive selection of human reticulocytes by immunomagnetic separation. Blood 76:2397–2403PubMedGoogle Scholar
  13. 13.
    Fibach E, Rachmilewitz EA (1993) The two-step liquid culture: a novel procedure for studying maturation of human normal and pathological erythroid precursors. Stem Cells 11(Suppl 1):36–41PubMedCrossRefGoogle Scholar
  14. 14.
    Vaisman B, Konijn AM, Fibach E (1999) Isolation of large and pure samples of human erythroid precursors at different stages of maturation using immunomagnetic separation of cells from liquid cultures. Acta Haematol 101:135–139 doi:10.1159/000040939 PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag 2008

Authors and Affiliations

  1. 1.University of LiverpoolLiverpoolUK

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