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Primary follicular lymphoma of the cervix uteri: a review

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Abstract

Primary non-Hodgkin’s lymphoma of the cervix is a rare disease, of which a subgroup of follicular lymphoma constitutes only 8.5%. There is not an established treatment protocol neither for primary cervical lymphoma nor for its follicular subgroup. We presented a case with Ann Arbor stage IEA (Extra-nodal involvement and absence of weight loss, fever, night sweat) primary follicular lymphoma of the cervix. She was treated with chemotherapy followed by pelvic radiotherapy. Upon relapse with a nodal neck mass, she was treated with rituximab alone. She remained well for 23 months after rituximab. In the 39 months of follow-up, there was no evidence of disease. In the light of our case, we reviewed the reported cases of primary follicular lymphoma of the cervix while discussing their treatment protocols and the cases of primary cervix lymphoma treated with rituximab.

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Acknowledgments

This study was supported by the Akdeniz University Scientific Research Projects Unit.

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Authors and Affiliations

  1. Department of Radiation Oncology, Akdeniz University, School of Medicine, Antalya, 07070, Turkey

    Aylin Fidan Korcum & Gamze Aksu

  2. Department of Hematology, Akdeniz University, School of Medicine, Antalya, 07070, Turkey

    Ihsan Karadogan

  3. Department of Radiology, Akdeniz University, School of Medicine, Antalya, 07070, Turkey

    Ayse Aralasmak

  4. Department of Pathology, Akdeniz University, School of Medicine, Antalya, 07070, Turkey

    Gulgun Erdogan

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  1. Aylin Fidan Korcum
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  2. Ihsan Karadogan
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  5. Gulgun Erdogan
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Correspondence to Aylin Fidan Korcum.

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Korcum, A.F., Karadogan, I., Aksu, G. et al. Primary follicular lymphoma of the cervix uteri: a review. Ann Hematol 86, 623–630 (2007). https://doi.org/10.1007/s00277-007-0328-0

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