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Successful treatment of thrombocytopenia in primary antiphospholipid antibody syndrome with the anti-CD20 antibody rituximab—monitoring of antiphospholipid and anti-GP antibodies: a case report

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References

  1. Ahn ER, Lander G, Bidot CJ, Jy W, Ahn YS (2005) Long-term remission from life-threatening hypercoagulable state associated with lupus anticoagulant (LA) following rituximab therapy. Am J Hematol 78:127–129

    Article  PubMed  Google Scholar 

  2. Braendstrup P, Bjerrum OW, Nielsen OJ, Jensen BA, Clausen NT, Hansen PB, Andersen I, Schmidt K, Andersen TM, Peterslund NA, Birgens HS, Plesner T, Pedersen BB, Hasselbalch HC (2005) Rituximab chimeric anti-CD20 monoclonal antibody treatment for adult refractory idiopathic thrombocytopenic purpura. Am J Hematol 78:275–280

    Article  PubMed  CAS  Google Scholar 

  3. Cooper N, Stasi R, Cunningham-Rundles S, Feuerstein MA, Leonard JP, Amadori S, Bussel JB (2004) The efficacy and safety of B-cell depletion with anti-CD20 monoclonal antibody in adults with chronic immune thrombocytopenic purpura. Br J Haematol 125:232–239

    Article  PubMed  CAS  Google Scholar 

  4. Erdozain JG, Ruiz-Irastorza G, Egurbide MV, Aguirre C (2004) Sustained response to rituximab of autoimmune hemolytic anemia associated with antiphospholipid syndrome. Haematologica 89:ECR34

    PubMed  CAS  Google Scholar 

  5. Galli M, Daldossi M, Barbui T (1994) Anti-glycoprotein Ib/IX and IIb/IIIa antibodies in patients with antiphospholipid antibodies. Thromb Haemost 71:571–575

    PubMed  CAS  Google Scholar 

  6. Godeau B, Piette JC, Fromont P, Intrator L, Schaeffer A, Bierling P (1997) Specific antiplatelet glycoprotein autoantibodies are associated with the thrombocytopenia of primary antiphospholipid syndrome. Br J Haematol 98:873–879

    Article  PubMed  CAS  Google Scholar 

  7. Panzer S, Gschwandtner ME, Hutter D, Spitzauer S, Pabinger I (1997) Specificities of platelet autoantibodies in patients with lupus anticoagulants in primary antiphospholipid syndrome. Ann Hematol 74:239–242

    Article  PubMed  CAS  Google Scholar 

  8. Stasi R, Pagano A, Stipa E, Amadori S (2001) Rituximab chimeric anti-CD20 monoclonal antibody treatment for adults with chronic idiopathic thrombocytopenic purpura. Blood 98:952–957

    Article  PubMed  CAS  Google Scholar 

  9. Stasi R, Stipa E, Forte V, Meo P, Amadori S (2002) Variable patterns of response to rituximab treatment in adults with chronic idiopathic thrombocytopenic purpura. Blood 99:3872–3873

    Article  PubMed  CAS  Google Scholar 

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Trappe, R., Loew, A., Thuss-Patience, P. et al. Successful treatment of thrombocytopenia in primary antiphospholipid antibody syndrome with the anti-CD20 antibody rituximab—monitoring of antiphospholipid and anti-GP antibodies: a case report. Ann Hematol 85, 134–135 (2006). https://doi.org/10.1007/s00277-005-0028-6

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  • DOI: https://doi.org/10.1007/s00277-005-0028-6

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