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Acute myocardial infarction after bone marrow transplantation: an unsuspected late complication

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Abstract

Acute myocardial infarction is a common disease rarely seen as a complication of bone marrow transplantation in young patients. We report on a 25-year-old patient 3.5 years after bone marrow transplantation who suffered an acute anterior wall myocardial infarction complicated by cardiogenic shock. The patient was treated with thrombolysis and emergent coronary angioplasty but died a few hours following admission. We suggest that the combination of low-dose chest irradiation and prolonged immunosuppression with graft-versus-host disease contributed to the development of the coronary artery disease in this patient. Though rarely encountered, physicians caring for young patients after bone marrow transplantation should be aware of potential ischemic complications.

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Authors and Affiliations

  1. Department of Internal Medicine, Hadassah University Hospital Mount Scopus, Hadassah-Hebrew University Medical School, Jerusalem, Israel

    M. E. Gatt & D. Leibowitz

  2. Hematology Unit, Hadassah University Hospital Mount Scopus, Hadassah-Hebrew University Medical School, POB 24035, 91240, Jerusalem, Israel

    M. E. Gatt, D. Liebster & Y. Matzner

Authors
  1. M. E. Gatt
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  2. D. Liebster
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  3. D. Leibowitz
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  4. Y. Matzner
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Corresponding author

Correspondence to M. E. Gatt.

Additional information

This paper is dedicated to Prof. Yaacov Matzner who died tragically in an airplane crash on 24 November 2001 near Zurich airport while returning from an international hematology conference held in Berlin.

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Gatt, M.E., Liebster, D., Leibowitz, D. et al. Acute myocardial infarction after bone marrow transplantation: an unsuspected late complication. Ann Hematol 82, 136–138 (2003). https://doi.org/10.1007/s00277-002-0605-x

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  • DOI: https://doi.org/10.1007/s00277-002-0605-x

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