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Testicular infiltration in acute myeloid leukemia with complex karyotype including t(8;21)

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Abstract.

Testicular infiltration is a well-known complication in acute lymphoblastic leukemia. In acute myeloid leukemia (AML), it has rarely been described and preferably occurred in cases with myelomonocytic or monoblastic differentiation. We report on a patient with AML with complex karyotype including translocation t(8;21) who presented with testicular infiltration at the time of his third bone marrow relapse. Cytological analysis of the specimen showed infiltration with blasts displaying the typical morphology of AML with translocation t(8;21) and comparable to those detected in the bone marrow. Fine needle aspiration cytology might suffice in these cases and should be performed if testicular involvement is suspected.

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Authors and Affiliations

  1. Medizinische Klinik II, St. Johannes Hospital, An der Abtei 7-11, 47166 Duisburg, Germany, Germany

    A. Giagounidis, M. Heinsch & C. Aul

  2. Institut für Humangenetik und Anthropologie, Heinrich-Heine-Universität Düsseldorf, Moorenstr. 5, 40225 Düsseldorf, Germany, Germany

    B. Hildebrandt

  3. Institut für Pathologie, Heinrich-Heine-Universität Düsseldorf, Moorenstr. 5, 40225 Düsseldorf, Germany, Germany

    S. Braunstein

  4. Medizinische Klinik und Poliklinik A, Heinrich-Heine-Universität Düsseldorf, Moorenstrasse 5, 40225 Düsseldorf, Germany, Germany

    M. Aivado & U. Germing

Authors
  1. A. Giagounidis
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  2. B. Hildebrandt
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  3. S. Braunstein
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  4. M. Aivado
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  5. U. Germing
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  6. M. Heinsch
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  7. C. Aul
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Giagounidis, A., Hildebrandt, B., Braunstein, S. et al. Testicular infiltration in acute myeloid leukemia with complex karyotype including t(8;21). Ann Hematol 81, 115–118 (2002). https://doi.org/10.1007/s00277-001-0396-5

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  • DOI: https://doi.org/10.1007/s00277-001-0396-5

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