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Educational stereoscopic representation of a step-by-step brain white fiber dissection according to Klingler’s method

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Surgical and Radiologic Anatomy Aims and scope Submit manuscript

Abstract

Background

Understanding and teaching the three-dimensional architecture of the brain remains difficult because of the intricate arrangement of grey nuclei within white matter tracts. Although cortical area functions have been well studied, educational and three-dimensional descriptions of the organization of deep nuclei and white matter tracts are still missing.

Objective

We propose herein a detailed step-by-step dissection of the lateral aspect of a left hemisphere using the Klingler method and provide high-quality stereoscopic views with the aim to help teach medical students or surgeons the three-dimensional anatomy of the brain.

Methods

Three left hemispheres were extracted and prepared. Then, according to the Klingler method, dissections were carried out from the lateral aspect. Photographs were taken at each step and were modified to provide stereoscopic three-dimensional views.

Results

Gray and white structures were described: cortex, claustrum, putamen, pallidum, caudate nucleus, amygdala; U-fibers, external and internal capsules, superior longitudinal fasciculus, frontal aslant fasciculus, uncinate fasciculus, inferior fronto-occipital fasciculus, inferior longitudinal fasciculus, corticospinal fasciculus, corona radiata, anterior commissure, and optic radiations.

Conclusion

This educational stereoscopic presentation of an expert dissection of brain white fibers and basal ganglia would be of value for theoretical or hands-on teaching of brain anatomy; labeling and stereoscopy could, moreover, improve the teaching, understanding, and memorizing of brain anatomy. In addition, this could be also used for the creation of a mental map by neurosurgeons for the preoperative planning of brain tumor surgery.

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Data availability

The datasets analyzed in the current study are directly available as Figures and supplementary material.

Abbreviations

AF:

Arcuate fasciculus

IFOF:

Inferior fronto-occipital fasciculus

ILF:

Inferior longitudinal fasciculus

FAT:

Frontal aslant tract

SLF:

Superior longitudinal fasciculus

UF:

Uncinate fasciculus

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Acknowledgements

We thank Dr P. Robinson for his help in manuscript preparation.

Funding

None.

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Authors and Affiliations

  1. Département de Neurochirurgie, Hôpital Pierre Wertheimer, Hospices Civils de Lyon, 59 Bd Pinel, 69677, Lyon Cedex, France

    Timothée Jacquesson, Émile Simon, Claire Haegelen, Patrick Mertens & Thiébaud Picart

  2. Laboratoire d’Anatomie Rockefeller, Université de Lyon 1, 8 Avenue Rockefeller, 69003, Lyon, France

    Timothée Jacquesson, Idriss Djarouf, Émile Simon, Claire Haegelen & Patrick Mertens

  3. Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA

    Timothée Jacquesson, Idriss Djarouf, Émile Simon, Claire Haegelen & Patrick Mertens

  4. Department of Neurosurgery, Stanford University Medical Center, Stanford, CA, USA

    Juan Fernandez-Miranda

Authors
  1. Timothée Jacquesson
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  2. Idriss Djarouf
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  3. Émile Simon
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  4. Claire Haegelen
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  5. Patrick Mertens
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  6. Thiébaud Picart
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  7. Juan Fernandez-Miranda
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Contributions

TJ and ID wrote the manuscript and took pictures ES CH and PM reviewed the manuscript in its anatomical purpose TP and JFM reviewed the manuscript for white tract anatomy accuracy

Corresponding author

Correspondence to Timothée Jacquesson.

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Competing interests

The authors declare no competing interests.

Ethical approval

This study has been approved by the by the Committee for Oversight of Research Involving the Dead of the University of Pittsburgh Medical Center.

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Jacquesson, T., Djarouf, I., Simon, É. et al. Educational stereoscopic representation of a step-by-step brain white fiber dissection according to Klingler’s method. Surg Radiol Anat 46, 303–311 (2024). https://doi.org/10.1007/s00276-024-03305-0

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  • DOI: https://doi.org/10.1007/s00276-024-03305-0

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