Contrast opacification difference of mural artery and the transluminal attenuation gradient on coronary computed tomography angiography for detection of systolic compression of myocardial bridge
Myocardial bridges (MB) have traditionally been considered a benign condition, but recent studies have demonstrated that the clinical complications can be dangerous. The transluminal attenuation gradient (TAG) obtained from coronary computed tomography angiography (CCTA) data (Retrospective ECG-triggered method) has been used in detecting significant stenosis in coronary artery caused by atherosclerosis. Contrast opacification difference (COD) was the parameters calculated as the change between attenuation of mural artery and the median attenuation of presumptive vessel segment; it was evaluated along with TAGstandardized (TAGs) and MB length for predicting MB with systolic compression (MB-SC) in patients diagnosed as MB in left anterior descending coronary artery (LAD) by CCTA or invasive coronary angiograph (ICA).
A total of 107 MB patients were divided into three groups based on systolic compression (SC), including: Group 1 (MB without SC); Group 2 (MB with mild SC); and Group 3 (MB with significant SC). ANOVA and Kruskal–Wallis analysis indicated TAGs showed the most significant differences for MB identification.
This study revealed that TAGs decreasing and COD increasing were dominated in MB with significant SC.
COD had a higher sensitivity and a higher negative predictive value for detecting MB with significant SC than TAGs.
KeywordsMyocardial bridge Contrast opacification difference Transluminal attenuation gradient Left anterior descending coronary artery Myocardial bridge with systolic compression
Guarantor of integrity of the entire study: YX. Study concepts: XW. Study design: YX. Definition of intellectual content: WX. Literature research: XW. Clinical studies: YX. Experimental studies: WX, FC. Data acquisition: SG, FC. Data analysis: SG. Statistical analysis: YX. Manuscript preparation: YX. Manuscript editing: YX. Manuscript review: YX.
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Conflict of interest
All authors declare that they have no any conflict of interest.
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