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Percutaneous Ablation of Metastatic Lymph Nodes: An Insight from the Comparison of Efficacy and Safety Between Cryoablation and Radiofrequency Ablation

  • Clinical Investigation
  • Non-Vascular Interventions
  • Published:
CardioVascular and Interventional Radiology Aims and scope Submit manuscript

Abstract

Purpose

To retrospectively compare efficacy and safety of computed tomography (CT)-guided percutaneous ablation of metastatic lymph nodes (LN) between cryoablation (CA) and radiofrequency ablation (RFA).

Materials and Methods

A bi-central institutional database research identified 28 patients (42 metastatic LNs) who underwent percutaneous CT-guided ablation. RFA group included 18 patients/26 tumors; CA group included 10 patients/16 tumors. Contrast-enhanced CT or MRI was used for post-ablation follow-up. Patient and tumor characteristics, technical and clinical success on a per tumor and a per patient basis and complication rates were recorded, evaluated and compared between the 2 groups.

Results

Both RFA and CA groups had the same median tumor size (2.00 vs. 2.20 cm, p = 0.257), the same median follow-up time (20.50 vs. 20.00 months, p = 0.923) and the same median length of hospital stay (1.00 vs. 1.00 days, p = 0.283). CA group had a higher median procedure time (110.50 vs. 52.00 min, p = 0.001). On a per lesion basis, the overall complete response post-ablation was 88.46% (23/26 lesions) in the RFA and 93.75% (15/16 lesions) in the CA group; no association was revealed between local tumor control and ablation technique (p = 0.709). No complications were recorded in both Groups. On a per patient basis, CA had a longer disease-free interval (24.00 vs. 14.50, p = 0.012) which, however, did not affect the overall survival between the two techniques (26.0 vs. 22.0, p = 0.099 for CA and RFA respectively).

Conclusion

Our limited data suggest that CT-guided RFA and CA are equally effective on terms of efficacy and safety for the treatment of metastatic lymph nodes.

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Funding

This study was not supported by any funding.

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Authors and Affiliations

  1. 2nd Department of Radiology, Medical School, University General Hospital “ATTIKON”, National and Kapodistrian University of Athens,, 1 Rimini str, 12462, Haidari/Athens, Greece

    Dimitrios K Filippiadis, Eleni Georgiadi, Alexis Kelekis & Nikolaos Kelekis

  2. Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore, 308433, Singapore

    Uei Pua, Lawrence Han Hwee Quek & Guo Yuan How

Authors
  1. Dimitrios K Filippiadis
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  2. Uei Pua
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  3. Eleni Georgiadi
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  4. Lawrence Han Hwee Quek
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  5. Alexis Kelekis
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  6. Guo Yuan How
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  7. Nikolaos Kelekis
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Correspondence to Dimitrios K Filippiadis.

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Filippiadis, D.K., Pua, U., Georgiadi, E. et al. Percutaneous Ablation of Metastatic Lymph Nodes: An Insight from the Comparison of Efficacy and Safety Between Cryoablation and Radiofrequency Ablation. Cardiovasc Intervent Radiol 45, 1134–1140 (2022). https://doi.org/10.1007/s00270-022-03191-2

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  • DOI: https://doi.org/10.1007/s00270-022-03191-2

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