To compare the Celect and Denali filters in terms of complex filter retrieval and indwelling complications after a 2-month indwelling time.
Materials and Methods
In this prospective, randomized trial, 153 subjects were assessed for eligibility between May 2016 and July 2018. A total of 136 participants were randomly assigned to receive either Celect (n = 68) or Denali (n = 68) filter placement in the infrarenal inferior vena cava. Tilt angles at placement and retrieval and rates of overall filter retrieval, indwelling complication, and complex retrieval were compared.
Of 136 participants (mean age, 62 ± 12.8 years, 55 male), 24 (17.6%) were lost to follow-up. The mean indwelling time of filter was 60.4 ± 7 days and there was no significant difference in the baseline characteristics between the two groups. Filter retrieval was successful in all participants (112/112, 100%). Significantly higher rates of filter tilt > 15° (n = 8) and strut penetration (n = 14) were found with the Celect filter than with the Denali filter (1 significant tilt and 1 penetration) (P = 0.033 and 0.001, respectively). No filter fractures were observed and there was no significant difference in tip embedment, filter fracture, filter migration, or mean fluoroscopy times. There were 3 cases of complex retrieval (1 for Denali vs. 2 for Celect, P = 0.500), for which the loop-snare technique was used.
Denali filters demonstrated significantly lower rates of tilt angle > 15° and strut penetration. However, there was no significant difference in the complex filter retrieval rate between the Celect and Denali filters.
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Bick RL. Hereditary and acquired thrombophilia. Part I. Preface. Semin Thromb Hemost. 1999;25(3):251–3.
Athanasoulis CA, Kaufman JA, Halpern EF, Waltman AC, Geller SC, Fan CM. Inferior vena caval filters: review of a 26-year single-center clinical experience. Radiology. 2000;216(1):54–66.
Decousus H, Leizorovicz A, Parent F, et al. A clinical trial of vena caval filters in the prevention of pulmonary embolism in patients with proximal deep-vein thrombosis. Prevention du risque d’embolie pulmonaire par interruption cave study group. N Engl J Med. 1998;338(7):409–15.
Ferris EJ, McCowan TC, Carver DK, McFarland DR. Percutaneous inferior vena caval filters: follow-up of seven designs in 320 patients. Radiology. 1993;188(3):851–6.
Jia Z, Fuller TA, McKinney JM, et al. Utility of retrievable inferior vena cava filters: a systematic literature review and analysis of the reasons for nonretrieval of filters with temporary indications. Cardiovasc Intervent Radiol. 2018;41(5):675–82.
Ray CE Jr, Mitchell E, Zipser S, Kao EY, Brown CF, Moneta GL. Outcomes with retrievable inferior vena cava filters: a multicenter study. J Vasc Interv Radiol. 2006;17(10):1595–604.
Lee MJ, Valenti D, de Gregorio MA, Minocha J, Rimon U, Pellerin O. The CIRSE retrievable IVC filter registry: retrieval success rates in practice. Cardiovasc Intervent Radiol. 2015;38(6):1502–7.
Uberoi R, Tapping CR, Chalmers N, Allgar V. British society of interventional radiology (BSIR) inferior vena cava (IVC) filter registry. Cardiovasc Intervent Radiol. 2013;36(6):1548–61.
Montgomery JP, Kaufman JA. A critical review of available retrievable inferior vena cava filters and future directions. Semin Interv Radiol. 2016;33(2):79–87.
Kleedehn M, Moore K, Longo K, et al. An analysis of factors associated with increased fluoroscopy time or the need for complex techniques at IVC filter retrieval. Eur Radiol. 2019;29:1931.
Bos AS, Tullius T, Patel M, et al. Indwelling and retrieval complications of denali and celect infrarenal vena cava filters. J Vasc Interv Radiol. 2016;27(7):1021–6.
Ramaswamy RS, Jun E, van Beek D, et al. Denali, tulip, and option inferior vena cava filter retrieval: a single center experience. Cardiovasc Intervent Radiol. 2018;41(4):572–7.
Ryu RK, Desai K, Karp J, et al. A comparison of retrievability: celect versus option filter. J Vasc Interv Radiol. 2015;26(6):865–9.
Zhou D, Spain J, Moon E, McLennan G, Sands MJ, Wang W. Retrospective review of 120 celect inferior vena cava filter retrievals: experience at a single institution. J Vasc Interv Radiol. 2012;23:1557–63.
Iliescu B, Haskal ZJ. Advanced techniques for removal of retrievable inferior vena cava filters. Cardiovasc Intervent Radiol. 2012;35:741–50.
Caplin DM, Nikolic B, Kalva SP, Ganguli S, Saad WE, Zuckerman DA. Quality improvement guidelines for the performance of inferior vena cava filter placement for the prevention of pulmonary embolism. J Vasc Interv Radiol. 2011;22(11):1499–506.
Dinglasan LA, Oh JC, Schmitt JE, Trerotola SO, Shlansky-Goldberg RD, Stavropoulos SW. Complicated inferior vena cava filter retrievals: associated factors identified at preretrieval CT. Radiology. 2013;266(1):347–54.
Jia Z, Fuller TA, McKinney JM, et al. Utility of retrievable inferior vena cava filters: a systematic literature review and analysis of the reasons for nontrieval of filters with temporary indications. Cardiovasc Intervent Radiol. 2018;41:675–82.
Clements W, Moriarty HK, Paul E, Goh GS. Stratification of pre-procedure risk factors associated with difficult-to-remove inferior vena cava (IVC) filters: a 6-year retrospective analysis at a tertiary center. Cardiovasc Intervent Radiol. 2020;43(2):238–45.
Stavropoulos SW, Chen JX, Sing RF, Elmasri F, Silver MJ, Powell A, et al. Analysis of the final denali trial data: a prospective, multicenter study of the denali inferior vena cava filter. J Vasc Interv Radiol. 2016;27:1531-1538.e1531.
Wang W, Zhou D, Obuchowski N, Spain J, An T, Moon E. Fracture and migration of celect inferior vena cava filters: a retrospective review of 741 consecutive implantations. J Vasc Interv Radiol. 2013;24:1719–22.
Jia Z, Wu A, Tam M, Spain J, McKinney JM, Wang W. Caval penetration by inferior vena cava filters: a systematic literature review of clinical significance and management. Circulation. 2015;132:944–52.
Dowell JD, Wagner D, Elliott E, Yildiz VO, Pan X. Factors associated with advanced inferior vena cava filter removals: a single-center retrospective study of 203 patients over 7 years. Cardiovasc Intervent Radiol. 2016;39(2):218–26.
Dabbagh O, Nagam N, Chitima-Matsiga R, Bearelly S, Bearelly D. Retrievable inferior vena cava filters are not getting retrieved: where is the gap? Thromb Res. 2010;126:493–7.
Kim HS, Young MJ, Narayan AK, Hong K, Liddell RP, Streiff MB. A comparison of clinical outcomes with retrievable and permanent inferior vena cava filters. J Vasc Interv Radiol. 2008;19:393–9.
Sadri L, Rogers A, Sharma D, Tunis J, Sullivan T, Pineda DM. A survey of patients lost to follow-up after inferior vena cava filter placement. J Vasc Surg Venous Lymphat Disord. 2020;8(3):365–70.
Minocha J, Idakoji I, Riaz A, Karp J, Gupta R, Chrisman HB, et al. Improving inferior vena cava filter retrieval rates: impact of a dedicated inferior vena cava filter clinic. J Vasc Interv Radiol. 2010;21:1847–51.
Salei A, Raborn J, Manapragada PP, Stoneburner CG, Aal AKA, Gunn AJ. Effect of a dedicated inferior vena cava filter retrieval program on retrieval rates and number of patients lost to follow-up. Diagn Interv Radiol. 2020;26:40–4.
Lee BE, Van Allan RJ, Friedman ML, Lipshutz HG. Complications and retrieval characteristics of celect platinum inferior vena cava filters. J Vasc Surg Venous Lymphat Disord. 2018;6:163–72.
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Han, K., Kim, MD., Kim, G.M. et al. Comparison of Retrievability and Indwelling Complications of Celect and Denali Infrarenal Vena Cava Filters: A Randomized, Controlled Trial. Cardiovasc Intervent Radiol 44, 1536–1542 (2021). https://doi.org/10.1007/s00270-021-02928-9
- Pulmonary embolism
- Deep venous thrombosis
- Inferior vena cava