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Etiology, Diagnosis and Management of Aortitis

A Correction to this article was published on 03 June 2020

This article has been updated

Abstract

Aortitis includes conditions with infectious or non-infectious etiology, characterized by inflammatory changes in one or more layers in aortic wall. Age at onset, geographic predilections, distribution and pattern of involvement in aorta, its branches and pulmonary arteries, and systemic associations provide a clue to etiology. Clinical presentations are often non-specific. An integrated approach including clinical, laboratory and imaging assessment is essential to confirm diagnosis and plan treatment. Assessment of disease activity is the key as it influences timing and outcome of treatment. Markers of activity include clinical, laboratory and imaging. Medical management remains the first-line therapy. Revascularization is indicated in the presence of hemodynamically significant stenosis and inactive disease. In the presence of flash pulmonary edema, left ventricular dysfunction or hypertensive encephalopathy, revascularization is performed irrespective of disease activity. Endovascular management is favored over surgery due to its high success and low restenosis rates. Symptomatic aneurysmal disease is usually managed by surgery.

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Change history

  • 03 June 2020

    In the original article, the section “Fact Sheet” was not published. This section should give the reader an overview on the most important take-home messages on aortitis. Please see below the missing section.

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Sharma, S., Pandey, N.N., Sinha, M. et al. Etiology, Diagnosis and Management of Aortitis. Cardiovasc Intervent Radiol 43, 1821–1836 (2020). https://doi.org/10.1007/s00270-020-02486-6

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Keywords

  • Aortitis
  • Giant cell arteritis
  • Takayasu arteritis
  • Disease activity