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Endovascular Occlusion of Neovascularization as a Treatment for Persistent Pain After Total Knee Arthroplasty

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Abstract

Approximately 20% of patients have persistent unexplained pain after total knee arthroplasty (TKA). Currently available treatments are unsatisfactory. The present report describes four patients in whom transcatheter arterial embolization had a remarkable effect on pain after TKA. Abnormal neovessels were identified in all patients. For 48 h, one patient experienced remarkable postprocedural pain at the inner side of the knee that was subsided by level 1 analgesics and another patient development of a spontaneous skin ulceration resolving within 8 days. The mean Knee injury and Osteoarthritis Outcome Score pain subtotal had increased from 39 to 82 one month after treatment. Endovascular occlusion of neovascularization, decreasing chronic inflammation and the growth of unmyelinated sensory nerves may be treatment options for persistent unexplained pain following TKA.

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Funding

This study was not supported by any funding.

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Authors and Affiliations

  1. Neurointerventional and Interventional Vascular Unit, Université Côte d’Azur (UCA), Hôpital Pasteur 2, CHU Nice, 30 Voie Romaine, Nice, France

    Yves Chau & Jacques Sédat

  2. Department of Rheumatology, Université Côte d’Azur (UCA), Hôpital Pasteur 2, Nice, France

    Christian Roux & Véronique Breuil

  3. Department of Orthopedic Surgery, Université Côte d’Azur (UCA), Hôpital Pasteur 2, Nice, France

    Christophe Trojani & Jean-François Gonzalez

  4. Department of Osteointerventional Radiology, Université Côte d’Azur (UCA), Hôpital Pasteur 2, Nice, France

    Nicolas Amoretti

Authors
  1. Yves Chau
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  2. Christian Roux
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  3. Véronique Breuil
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  4. Christophe Trojani
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  5. Jean-François Gonzalez
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  6. Nicolas Amoretti
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  7. Jacques Sédat
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Corresponding author

Correspondence to Yves Chau.

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The authors declare that they have no conflict of interest.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. This study has been approved by local institutional review board.

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Informed consent was obtained from all individual participants included in the study.

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Chau, Y., Roux, C., Breuil, V. et al. Endovascular Occlusion of Neovascularization as a Treatment for Persistent Pain After Total Knee Arthroplasty. Cardiovasc Intervent Radiol 43, 787–790 (2020). https://doi.org/10.1007/s00270-020-02449-x

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  • DOI: https://doi.org/10.1007/s00270-020-02449-x

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