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Effect of Transcatheter Arterial Microembolization on Phantom Limb Pain Persisting for 17 Years

Abstract

Phantom limb pain is a frequent consequence of the amputation; currently available treatments are far from satisfactory. The present report describes a case in which transcatheter arterial microembolization had a remarkable curative effect on phantom limb pain persisting for 17 years. The patient began feeling phantom limb sensations and brief intermittent pain following lower limb amputation above the knee in 2001. The frequency, intensity, and duration of the pain increased over time, and it was resistant to conservative treatments. Following transcatheter arterial microembolization in 2018, patient immediately experienced marked improvement. The pain has been infrequent, much less intense, and did not interfere with daily life 6 months posttreatment. Transcatheter arterial microembolization could be an alternative treatment option for phantom limb pain.

Level of Evidence

IV, Case Report

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References

  1. Nikolajsen L, Christensen KF, Haroutiunian S. Phantom limb pain: treatment strategies. Pain Manag. 2013;3(6):421–4.

    Article  PubMed  Google Scholar 

  2. Alviar MJ, Hale T, Dungca M. Pharmacologic interventions for treating phantom limb pain. Cochrane Database Syst Rev. 2016;10:CD006380.

    PubMed  Google Scholar 

  3. Mapp PI, Walsh DA. Mechanisms and targets of angiogenesis and nerve growth in osteoarthritis. Nat Rev Rheumatol. 2012;8(7):390–8.

    Article  CAS  PubMed  Google Scholar 

  4. Walsh DA, Bonnet CS, Turner EL, Wilson D, Situ M, McWilliams DF. Angiogenesis in the synovium and at the osteochondral junction in osteoarthritis. Osteoarthr Cartil. 2007;15:743–51.

    Article  CAS  PubMed  Google Scholar 

  5. Alfredson H, Ohberg L, Forsgren S. Is vasculo-neural ingrowth the cause of pain in chronic Achilles tendinosis? An investigation using ultrasonography and colour Doppler, immunohistochemistry, and diagnostic injections. Knee Surg Sports Traumatol Arthrosc. 2003;11:334–8.

    Article  PubMed  Google Scholar 

  6. Okuno Y, Iwamoto W, Matsumura N, Oguro S, Yasumoto T, Kaneko T, Ikegami H. Clinical outcomes of transcatheter arterial embolization for adhesive capsulitis resistant to conservative treatment. J Vasc Interv Radiol. 2017;28(2):161–7.

    Article  PubMed  Google Scholar 

  7. Okuno Y, Korchi AM, Shinjo T, Kato S, Kaneko T. Midterm clinical outcomes and MR imaging changes after transcatheter arterial embolization as a treatment for mild to moderate radiographic knee osteoarthritis resistant to conservative treatment. J Vasc Interv Radiol. 2017;28(7):995–1002.

    Article  PubMed  Google Scholar 

  8. Iwamoto W, Okuno Y, Matsumura N, Kaneko T, Ikegami H. Transcatheter arterial embolization of abnormal vessels as a treatment for lateral epicondylitis refractory to conservative treatment: a pilot study with a 2-year follow-up. J Shoulder Elb Surg. 2017;26(8):1335–41.

    Article  Google Scholar 

  9. Okuno Y, Matsumura N, Oguro S. Transcatheter arterial embolization using imipenem/cilastatin sodium for tendinopathy and enthesopathy refractory to nonsurgical management. J Vasc Interv Radiol. 2013;24:787–92.

    Article  PubMed  Google Scholar 

  10. Sumitani M, Miyauchi S, McCabe CS, Shibata M, Maeda L, Saitoh Y, Tashiro T, Mashimo T. Mirror visual feedback alleviates deafferentation pain, depending on qualitative aspects of the pain: a preliminary report. Rheumatology. 2008;47(7):1038–43.

    Article  CAS  PubMed  Google Scholar 

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Correspondence to Yuji Okuno.

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Shibuya, M., Yamamoto, M. & Okuno, Y. Effect of Transcatheter Arterial Microembolization on Phantom Limb Pain Persisting for 17 Years. Cardiovasc Intervent Radiol 42, 471–474 (2019). https://doi.org/10.1007/s00270-018-2109-7

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  • DOI: https://doi.org/10.1007/s00270-018-2109-7

Keywords

  • Arterial embolization
  • Phantom pain
  • Phantom limb pain
  • Abnormal neovessels
  • Embolization