CardioVascular and Interventional Radiology

, Volume 40, Issue 3, pp 331–342 | Cite as

CIRSE Guidelines on Percutaneous Vertebral Augmentation

  • Georgia TsoumakidouEmail author
  • Chow Wei Too
  • Guillaume Koch
  • Jean Caudrelier
  • Roberto Luigi Cazzato
  • Julien Garnon
  • Afshin Gangi
CIRSE Standards of Practice Guidelines


Vertebral compression fracture (VCF) is an important cause of severe debilitating back pain, adversely affecting quality of life, physical function, psychosocial performance, mental health and survival. Different vertebral augmentation procedures (VAPs) are used in order to consolidate the VCFs, relief pain,and whenever posible achieve vertebral body height restoration. In the present review we give the indications, contraindications, safety profile and outcomes of the existing percutaneous VAPs.


Vertebral compression fracture Osteoporosis Vertebroplasty Kyphoplasty Percutaneous bone implant techniques 


Compliance with Ethical Standards

Conflict of interest

All authors declare that they have no conflict of interest.


  1. 1.
    Phillips F. Minimal invasive treatment of osteoporotic vertebral compression fractures. Spine. 2003;28s:45–53.Google Scholar
  2. 2.
    Stallemeyer M, Zoarski G, Obuchowski A. Bernadette optimising patient selection in percutaneous vertebroplasty. Interv Radiol. 2003;14:683–96.CrossRefGoogle Scholar
  3. 3.
    Wade SW, Strader C, Fitzpatrick LA, Anthony MS. Sex- and age-specific incidence of non-traumatic fractures in selected industrialized countries. Arch Osteoporos. 2012;7:219–27.PubMedCrossRefGoogle Scholar
  4. 4.
    Johnell O, Kanis JA. An estimate of the worldwide prevalence and disability associated with osteoporotic fractures. Osteoporos Int. 2006;17:1726–33.PubMedCrossRefGoogle Scholar
  5. 5.
    Riggs BL, Melton LJ. The worldwide problem of osteoporosis: insights afforded by epidemiology. Bone. 1995;17:505S–11S.PubMedCrossRefGoogle Scholar
  6. 6.
    Kado DM, Duong T, Stone KL, Ensrud KE, Nevitt MC, Greendale GA, et al. Incident vertebral fractures and mortality in older women: a prospective study. Osteoporos Int. 2003;14:589–94.PubMedCrossRefGoogle Scholar
  7. 7.
    Lau E, Ong K, Kurtz S, Schmier J, Edidin A. Mortality following the diagnosis of a vertebral compression fracture in the medicare population. J Bone Joint Surg Am. 2008;90:1479–86.PubMedCrossRefGoogle Scholar
  8. 8.
    Leech JA, Dulberg C, Kellie S, Pattee L, Gay J. Relationship of lung function to severity of osteoporosis in women. Am Rev Respir Dis. 1990;141:68–71.PubMedCrossRefGoogle Scholar
  9. 9.
    Uhthoff HK, Jaworski ZF. Bone loss in response to long-term immobilisation. J Bone Joint Surg Br. 1978;60–B:420–9.PubMedGoogle Scholar
  10. 10.
    Kerschan-Schindl K, Patsch J, Kudlacek S, Gleiss A, Pietschmann P. Measuring quality of life with the German osteoporosis quality of life questionnaire in women with osteoporosis. Wien Klin Wochenschr. 2012;124:532–7.PubMedCrossRefGoogle Scholar
  11. 11.
    Venmans A, Lohle PNM, van Rooij WJ. Pain course in conservatively treated patients with back pain and a VCF on the spine radiograph (VERTOS III). Skeletal Radiol. 2014;43:13–8.PubMedCrossRefGoogle Scholar
  12. 12.
    Black DM, Palermo L, Nevitt MC, Genant HK, Christensen L, Cummings SR. Defining incident vertebral deformity: a prospective comparison of several approaches. The study of osteoporotic fractures research group. J Bone Miner Res. 1999;14:90–101.PubMedCrossRefGoogle Scholar
  13. 13.
    Galibert P, Deramond H, Rosat P, Le Gars D. Preliminary note on the treatment of vertebral angioma by percutaneous acrylic vertebroplasty. Neurochirurgie. 1987;33:166–8.PubMedGoogle Scholar
  14. 14.
    Lieberman IH, Togawa D, Kayanja MM. Vertebroplasty and kyphoplasty: filler materials. Spine J. 2005;5:S305–16.CrossRefGoogle Scholar
  15. 15.
    Robinson Y, Heyde CE, Försth P, Olerud C. Kyphoplasty in osteoporotic vertebral compression fractures—guidelines and technical considerations. J Orthop Surg Res. 2011;6:43.PubMedPubMedCentralCrossRefGoogle Scholar
  16. 16.
    McGraw JK, Lippert JA, Minkus KD, Rami PM, Davis TM, Budzik RF. Prospective evaluation of pain relief in 100 patients undergoing percutaneous vertebroplasty: results and follow-up. J Vasc Interv Radiol. 2002;13:883–6.PubMedCrossRefGoogle Scholar
  17. 17.
    Cortet B, Cotten A, Deprez X, Deramond H, Lejeune JP, Leclerc X, et al. Value of vertebroplasty combined with surgical decompression in the treatment of aggressive spinal angioma. Apropos of 3 cases. Rev Rhum Ed Fr. 1994;61:16–22.PubMedGoogle Scholar
  18. 18.
    Ide C, Gangi A, Rimmelin A, Beaujeux R, Maitrot D, Buchheit F, et al. Vertebral haemangiomas with spinal cord compression: the place of preoperative percutaneous vertebroplasty with methyl methacrylate. Neuroradiology. 1996;38:585–9.PubMedCrossRefGoogle Scholar
  19. 19.
    Gangi A, Wong L, Guth S. Percutaneous vertebroplasty: indications, techniques and results. Semin Interv Radiol. 2002;19:265–70.CrossRefGoogle Scholar
  20. 20.
    Cotten A, Deramond H, Cortet B, Lejeune JP, Leclerc X, Chastanet P, et al. Preoperative percutaneous injection of methyl methacrylate and N-butyl cyanoacrylate in vertebral hemangiomas. AJNR Am J Neuroradiol. 1996;17:137–42.PubMedGoogle Scholar
  21. 21.
    Gangi A, Guth S, Imbert JP, Marin H, Dietemann J-L. Percutaneous vertebroplasty: indications, technique, and results 1. Radiographics. 2003;23:e10.PubMedCrossRefGoogle Scholar
  22. 22.
    Kaemmerlen P, Thiesse P, Bouvard H, Biron P, Mornex F, Jonas P. Percutaneous vertebroplasty in the treatment of metastases. Technic and results. J Radiol. 1989;70:557–62.PubMedGoogle Scholar
  23. 23.
    Gangi A, Guth S, Imbert J. Percutaneous bone tumour management. Semin Interv Radiol. 2002;19:279–86.CrossRefGoogle Scholar
  24. 24.
    Murphy KJ, Deramond H. Percutaneous vertebroplasty in benign and malignant disease. Neuroimaging Clin N Am. 2000;10:535–45.PubMedGoogle Scholar
  25. 25.
    Shimony JS, Gilula LA, Zeller AJ, Brown DB. Percutaneous vertebroplasty for malignant compression fractures with epidural involvement. Radiology. 2004;232:846–53.PubMedCrossRefGoogle Scholar
  26. 26.
    Jensen ME, Kallmes DE. Percutaneous vertebroplasty in the treatment of malignant spine disease. Cancer J. 2002;8:194–206.PubMedCrossRefGoogle Scholar
  27. 27.
    Cortet B, Cotten A, Boutry N, Dewatre F, Flipo RM, Duquesnoy B, et al. Percutaneous vertebroplasty in patients with osteolytic metastases or multiple myeloma. Rev Rhum Engl Ed. 1997;64:177–83.PubMedGoogle Scholar
  28. 28.
    Deramond H, Galibert P, Debussche C. Vertebroplasty (abstr). Neuroradiology. 1991;33(supp):177–8.Google Scholar
  29. 29.
    Pedicelli A, Lozupone E, Gatto A, Gulino P, D’Argento F, Capozzi A, et al. Vertebra plana: reappraisal of a contraindication to percutaneous vertebroplasty. Eur J Radiol. 2013;82:2303–8.PubMedCrossRefGoogle Scholar
  30. 30.
    Magerl F, Aebi M, Gertzbein SD, Harms J, Nazarian S. A comprehensive classification of thoracic and lumbar injuries. Eur Spine J. 1994;3:184–201.PubMedCrossRefGoogle Scholar
  31. 31.
    Chaudhary SB, Hullinger H, Vives MJ. Management of acute spinal fractures in ankylosing spondylitis. ISRN Rheumatol. 2011;2011:150484.PubMedPubMedCentralCrossRefGoogle Scholar
  32. 32.
    Zoarski GH, Snow P, Olan WJ, Stallmeyer MJB, Dick BW, Hebel JR, et al. Percutaneous vertebroplasty for osteoporotic compression fractures: quantitative prospective evaluation of long-term outcomes. J Vasc Interv Radiol. 2002;13:139–48.PubMedCrossRefGoogle Scholar
  33. 33.
    Clark W, Bird P, Gonski P, Diamond TH, Smerdely P, McNeil HP, et al. Safety and efficacy of vertebroplasty for acute painful osteoporotic fractures (VAPOUR): a multicentre, randomised, double-blind, placebo-controlled trial. Lancet (London, England). 2016;388:1408–16.CrossRefGoogle Scholar
  34. 34.
    Mathis JM, Barr JD, Belkoff SM, Barr MS, Jensen ME, Deramond H. Percutaneous vertebroplasty: a developing standard of care for vertebral compression fractures. AJNR Am J Neuroradiol. 2001;22:373–81.PubMedGoogle Scholar
  35. 35.
    Kaufmann TJ, Jensen ME, Schweickert PA, Marx WF, Kallmes DF. Age of fracture and clinical outcomes of percutaneous vertebroplasty. AJNR Am J Neuroradiol. 2001;22:1860–3.PubMedGoogle Scholar
  36. 36.
    Brown DB, Gilula LA, Sehgal M, Shimony JS. Treatment of chronic symptomatic vertebral compression fractures with percutaneous vertebroplasty. AJR Am J Roentgenol. 2004;182:319–22.PubMedCrossRefGoogle Scholar
  37. 37.
    Garfin SR, Reilley MA. Minimally invasive treatment of osteoporotic vertebral body compression fractures. Spine J. 2002;2:76–80.PubMedCrossRefGoogle Scholar
  38. 38.
    Nieuwenhuijse MJ, van Erkel AR, Dijkstra PDS. Percutaneous vertebroplasty for subacute and chronic painful osteoporotic vertebral compression fractures can safely be undertaken in the first year after the onset of symptoms. J Bone Joint Surg Br. 2012;94:815–20.PubMedCrossRefGoogle Scholar
  39. 39.
    Kim HS, Kim SH, Ju CI, Kim SW, Lee SM, Shin H. The role of bone cement augmentation in the treatment of chronic symptomatic osteoporotic compression fracture. J Korean Neurosurg Soc. 2010;48:490–5.PubMedPubMedCentralCrossRefGoogle Scholar
  40. 40.
    Rad AE, Kallmes DF. Correlation between preoperative pain duration and percutaneous vertebroplasty outcome. Am J Neuroradiol. 2011;32:1842–5.PubMedCrossRefGoogle Scholar
  41. 41.
    Maynard AS, Jensen ME, Schweickert PA, Marx WF, Short JG, Kallmes DF. Value of bone scan imaging in predicting pain relief from percutaneous vertebroplasty in osteoporotic vertebral fractures. AJNR Am J Neuroradiol. 2000;21:1807–12.PubMedGoogle Scholar
  42. 42.
    Peh WCG, Gilula LA. Percutaneous vertebroplasty: indications, contraindications, and technique. Br J Radiol. 2003;76:69–75.PubMedCrossRefGoogle Scholar
  43. 43.
    Mathis JM, Wong W. Percutaneous vertebroplasty: technical considerations. J Vasc Interv Radiol. 2003;14:953–60.PubMedCrossRefGoogle Scholar
  44. 44.
    Hiwatashi A, Yoshiura T, Noguchi T, Togao O, Yamashita K, Kamano H, et al. Usefulness of cone-beam CT before and after percutaneous vertebroplasty. AJR Am J Roentgenol. 2008;191:1401–5.PubMedCrossRefGoogle Scholar
  45. 45.
    Braak SJ, Zuurmond K, Aerts HCJ, van Leersum M, Overtoom TTT, van Heesewijk JPM, et al. Feasibility study of needle placement in percutaneous vertebroplasty: cone-beam computed tomography guidance versus conventional fluoroscopy. Cardiovasc Interv Radiol. 2013;36:1120–6.CrossRefGoogle Scholar
  46. 46.
    Seong J-Y, Kim J-S, Jung B, Lee S-H, Kang HY. CT-guided percutaneous vertebroplasty in the treatment of an upper thoracic compression fracture. Korean J Radiol. 2009;10:185–9.PubMedPubMedCentralCrossRefGoogle Scholar
  47. 47.
    Gangi A, Kastler BA, Dietemann JL. Percutaneous vertebroplasty guided by a combination of CT and fluoroscopy. AJNR Am J Neuroradiol. 1994;15:83–6.PubMedGoogle Scholar
  48. 48.
    Bonnard E, Foti P, Kastler A, Amoretti N. Percutaneous vertebroplasty under local anaesthesia: feasibility regarding patients’ experience. Eur Radiol. 2016. doi: 10.1007/s00330-016-4521-1.PubMedGoogle Scholar
  49. 49.
    Scroop R, Eskridge J, Britz GW. Paradoxical cerebral arterial embolization of cement during intraoperative vertebroplasty: case report. AJNR Am J Neuroradiol. 2002;23:868–70.PubMedGoogle Scholar
  50. 50.
    Uppin AA, Hirsch JA, Centenera LV, Pfiefer BA, Pazianos AG, Choi IS. Occurrence of new vertebral body fracture after percutaneous vertebroplasty in patients with osteoporosis. Radiology. 2003;226:119–24.PubMedCrossRefGoogle Scholar
  51. 51.
    White SM. Anaesthesia for percutaneous vertebroplasty. Anaesthesia. 2002;57:1229–30.PubMedGoogle Scholar
  52. 52.
    Martin JB, Jean B, Sugiu K, San Millán Ruíz D, Piotin M, Murphy K, et al. Vertebroplasty: clinical experience and follow-up results. Bone. 1999;25:11S–5S.PubMedCrossRefGoogle Scholar
  53. 53.
    Murphy DT, Korzan JR, Ouellette HA, Liu DM, Clarkson PW, Munk PL. Driven around the bend: novel use of a curved steerable needle. Cardiovasc Interv Radiol. 2013;36:531–5.CrossRefGoogle Scholar
  54. 54.
    Anselmetti GC, Manca A, Montemurro F, Tutton S, Chiara G, Battistella M, et al. Vertebroplasty using transoral approach in painful malignant involvement of the second cervical vertebra (C2): a single-institution series of 25 patients. Pain Physician. 2012;15:35–42.PubMedGoogle Scholar
  55. 55.
    Padovani B, Kasriel O, Brunner P, Peretti-Viton P. Pulmonary embolism caused by acrylic cement: a rare complication of percutaneous vertebroplasty. AJNR Am J Neuroradiol. 1999;20:375–7.PubMedGoogle Scholar
  56. 56.
    Komemushi A, Tanigawa N, Kariya S, Kojima H, Shomura Y, Sawada S. Radiation exposure to operators during vertebroplasty. J Vasc Interv Radiol JVIR. 2005;16:1327–32.PubMedCrossRefGoogle Scholar
  57. 57.
    Kallmes DF, Erwin O, Roy SS, Piccolo RG, Marx WF, Lee JK, et al. Radiation dose to the operator during vertebroplasty: prospective comparison of the use of 1-cc syringes versus an injection device. AJNR Am J Neuroradiol. 2003;24:1257–60.PubMedGoogle Scholar
  58. 58.
    Anselmetti GC, Marcia S, Saba L, Muto M, Bonaldi G, Carpeggiani P, et al. Percutaneous vertebroplasty: multi-centric results from EVEREST experience in large cohort of patients. Eur J Radiol. 2012;81:4083–6.PubMedCrossRefGoogle Scholar
  59. 59.
    Diamond TH, Champion B, Clark WA. Management of acute osteoporotic vertebral fractures: a nonrandomized trial comparing percutaneous vertebroplasty with conservative therapy. Am J Med. 2003;114:257–65.PubMedCrossRefGoogle Scholar
  60. 60.
    Blasco J, Martinez-Ferrer A, Macho J, San Roman L, Pomés J, Carrasco J, et al. Effect of vertebroplasty on pain relief, quality of life, and the incidence of new vertebral fractures: a 12-month randomized follow-up, controlled trial. J Bone Miner Res. 2012;27:1159–66.PubMedCrossRefGoogle Scholar
  61. 61.
    Klazen CA, Lohle PN, de Vries J, Jansen FH, Tielbeek AV, Blonk MC, et al. Vertebroplasty versus conservative treatment in acute osteoporotic vertebral compression fractures (Vertos II): an open-label randomised trial. Lancet. 2010;376:1085–92.PubMedCrossRefGoogle Scholar
  62. 62.
    Kallmes DF, Comstock BA, Heagerty PJ, Turner JA, Wilson DJ, Diamond TH, et al. A randomized trial of vertebroplasty for osteoporotic spinal fractures. N Engl J Med. 2009;361:569–79.PubMedPubMedCentralCrossRefGoogle Scholar
  63. 63.
    Buchbinder R, Osborne RH, Ebeling PR, Wark JD, Mitchell P, Wriedt C, et al. A randomized trial of vertebroplasty for painful osteoporotic vertebral fractures. N Engl J Med. 2009;361:557–68.PubMedCrossRefGoogle Scholar
  64. 64.
    Gangi A, Clark WA. Have recent vertebroplasty trials changed the indications for vertebroplasty? Cardiovasc Interv Radiol. 2010;33:677–80.CrossRefGoogle Scholar
  65. 65.
    Robinson Y, Olerud C. Vertebroplasty and kyphoplasty—a systematic review of cement augmentation techniques for osteoporotic vertebral compression fractures compared to standard medical therapy. Maturitas. 2012;72:42–9.PubMedCrossRefGoogle Scholar
  66. 66.
    Firanescu C, Lohle PN, de Vries J, Klazen CA, Juttmann JR, Clark W, et al. A randomised sham controlled trial of vertebroplasty for painful acute osteoporotic vertebral fractures (VERTOS IV). Trials. 2011;12:93.PubMedPubMedCentralCrossRefGoogle Scholar
  67. 67.
    Yuan W-H, Hsu H-C, Lai K-L. Vertebroplasty and balloon kyphoplasty versus conservative treatment for osteoporotic vertebral compression fractures: a meta-analysis. Medicine (Baltimore). 2016;95:e4491.CrossRefGoogle Scholar
  68. 68.
    Gill JB, Kuper M, Chin PC, Zhang Y, Schutt R. Comparing pain reduction following kyphoplasty and vertebroplasty for osteoporotic vertebral compression fractures. Pain Physician. 2007;10:583–90.PubMedGoogle Scholar
  69. 69.
    Shi M-M, Cai X-Z, Lin T, Wang W, Yan S-G. Is there really no benefit of vertebroplasty for osteoporotic vertebral fractures? A meta-analysis. Clin Orthop Relat Res. 2012;470:2785–99.PubMedPubMedCentralCrossRefGoogle Scholar
  70. 70.
    Chew C, Ritchie M, O’Dwyer PJ, Edwards R. A prospective study of percutaneous vertebroplasty in patients with myeloma and spinal metastases. Clin Radiol. 2011;66:1193–6.PubMedCrossRefGoogle Scholar
  71. 71.
    Chew C, Craig L, Edwards R, Moss J, O’Dwyer PJ. Safety and efficacy of percutaneous vertebroplasty in malignancy: a systematic review. Clin Radiol. 2011;66:63–72.PubMedCrossRefGoogle Scholar
  72. 72.
    Barr JD, Barr MS, Lemley TJ, McCann RM. Percutaneous vertebroplasty for pain relief and spinal stabilization. Spine (Phila. Pa. 1976). 2000;25:923–8.CrossRefGoogle Scholar
  73. 73.
    Deramond H, Depriester C, Galibert P, Le Gars D. Percutaneous vertebroplasty with polymethylmethacrylate. Technique, indications, and results. Radiol Clin North Am. 1998;36:533–46.PubMedCrossRefGoogle Scholar
  74. 74.
    Peh WCG, Gilula LA, Peck DD. Percutaneous vertebroplasty for severe osteoporotic vertebral body compression fractures. Radiology. 2002;223:121–6.PubMedCrossRefGoogle Scholar
  75. 75.
    Winking M, Stahl JP, Oertel M, Schnettler R, Böker DK. Treatment of pain from osteoporotic vertebral collapse by percutaneous PMMA vertebroplasty. Acta Neurochir (Wien). 2004;146:469–76.CrossRefGoogle Scholar
  76. 76.
    Kumar K, Verma AK, Wilson J, LaFontaine A. Vertebroplasty in osteoporotic spine fractures: a quality of life assessment. Can J Neurol Sci. 2005;32:487–95.PubMedCrossRefGoogle Scholar
  77. 77.
    Jensen ME, Evans AJ, Mathis JM, Kallmes DF, Cloft HJ, Dion JE. Percutaneous polymethylmethacrylate vertebroplasty in the treatment of osteoporotic vertebral body compression fractures: technical aspects. AJNR Am J Neuroradiol. 1997;18:1897–904.PubMedGoogle Scholar
  78. 78.
    Weill A, Chiras J, Simon JM, Rose M, Sola-Martinez T, Enkaoua E. Spinal metastases: indications for and results of percutaneous injection of acrylic surgical cement. Radiology. 1996;199:241–7.PubMedCrossRefGoogle Scholar
  79. 79.
    Cotten A, Dewatre F, Cortet B, Assaker R, Leblond D, Duquesnoy B, et al. Percutaneous vertebroplasty for osteolytic metastases and myeloma: effects of the percentage of lesion filling and the leakage of methyl methacrylate at clinical follow-up. Radiology. 1996;200:525–30.PubMedCrossRefGoogle Scholar
  80. 80.
    Garland P, Gishen P, Rahemtulla A. Percutaneous vertebroplasty to treat painful myelomatous vertebral deposits—long-term efficacy outcomes. Ann Hematol. 2011;90:95–100.PubMedCrossRefGoogle Scholar
  81. 81.
    Cotten A, Boutry N, Cortet B, Assaker R, Demondion X, Leblond D, et al. Percutaneous vertebroplasty: state of the art. Radiographics. 1998;18:311–20.PubMedCrossRefGoogle Scholar
  82. 82.
    Guarnieri G, Ambrosanio G, Vassallo P, Pezzullo MG, Galasso R, Lavanga A, et al. Vertebroplasty as treatment of aggressive and symptomatic vertebral hemangiomas: up to 4 years of follow-up. Neuroradiology. 2009;51:471–6.PubMedCrossRefGoogle Scholar
  83. 83.
    Boschi V, Pogorelić Z, Gulan G, Perko Z, Grandić L, Radonić V. Management of cement vertebroplasty in the treatment of vertebral hemangioma. Scand J Surg. 2011;100:120–4.PubMedCrossRefGoogle Scholar
  84. 84.
    McGirt MJ, Parker SL, Wolinsky J-P, Witham TF, Bydon A, Gokaslan ZL. Vertebroplasty and kyphoplasty for the treatment of vertebral compression fractures: an evidenced-based review of the literature. Spine J. 2009;9:501–8.PubMedCrossRefGoogle Scholar
  85. 85.
    Saracen A, Kotwica Z. Complications of percutaneous vertebroplasty: an analysis of 1100 procedures performed in 616 patients. Medicine (Baltimore). 2016;95:e3850.CrossRefGoogle Scholar
  86. 86.
    McGraw JK, Cardella J, Barr JD, Mathis JM, Sanchez O, Schwartzberg MS, et al. Society of interventional radiology quality improvement guidelines for percutaneous vertebroplasty. J Vasc Interv Radiol. 2003;14:827–31.PubMedCrossRefGoogle Scholar
  87. 87.
    Francois K, Taeymans Y, Poffyn B. Successful management of a large pulmonary cement embolus following percutaneous vertebroplasty: report. Spine. 2003;28:E424–5.PubMedCrossRefGoogle Scholar
  88. 88.
    Martin DJ, Rad AE, Kallmes DF. Prevalence of extravertebral cement leakage after vertebroplasty: procedural documentation versus CT detection. Acta Radiol (Stockholm, Sweden 1987). 2012;53:569–72.CrossRefGoogle Scholar
  89. 89.
    Krueger A, Bliemel C, Zettl R, Ruchholtz S. Management of pulmonary cement embolism after percutaneous vertebroplasty and kyphoplasty: a systematic review of the literature. Eur Spine J. 2009;18:1257–65.PubMedPubMedCentralCrossRefGoogle Scholar
  90. 90.
    Gardos F, Depriester C, Cayrolle G. Long term observations of vertebral osteoporotic fractures treated by percutaneous vertebroplasty. Rheumatology. 2000;39:1410–4.CrossRefGoogle Scholar
  91. 91.
    Nagaraja S, Awada HK, Dreher ML, Gupta S, Miller SW. Vertebroplasty increases compression of adjacent IVDs and vertebrae in osteoporotic spines. Spine J. 2013;13(12):1872–80.PubMedCrossRefGoogle Scholar
  92. 92.
    Aquarius R, van der Zijden AM, Homminga J, Verdonschot N, Tanck E. Does bone cement in percutaneous vertebroplasty act as a stress riser? Spine (Phila. Pa. 1976). 1976;2013(38):2092–7.Google Scholar
  93. 93.
    Grados F, Depriester C, Cayrolle G, Hardy N, Deramond H, Fardellone P. Long-term observations of vertebral osteoporotic fractures treated by percutaneous vertebroplasty. Rheumatology (Oxford). 2000;39:1410–4.CrossRefGoogle Scholar
  94. 94.
    Kim SH, Kang HS, Choi JA, Ahn JM. Risk factors of new compression fractures in adjacent vertebrae after percutaneous vertebroplasty. Acta Radiol (Stockholm, Sweden 1987). 2004;45:440–5.CrossRefGoogle Scholar
  95. 95.
    Klazen CAH, Venmans A, de Vries J, van Rooij WJ, Jansen FH, Blonk MC, et al. Percutaneous vertebroplasty is not a risk factor for new osteoporotic compression fractures: results from VERTOS II. Am J Neuroradiol. 2010;31:1447–50.PubMedCrossRefGoogle Scholar
  96. 96.
    Trout AT, Kallmes DF. Does vertebroplasty cause incident vertebral fractures? A review of available data. Am J Neuroradiol. 2006;27:1397–403.PubMedGoogle Scholar
  97. 97.
    Kobayashi N, Numaguchi Y, Fuwa S, Uemura A, Matsusako M, Okajima Y, et al. Prophylactic vertebroplasty: cement injection into non-fractured vertebral bodies during percutaneous vertebroplasty. Acad Radiol. 2009;16:136–43.PubMedCrossRefGoogle Scholar
  98. 98.
    Yen CH, Teng MMH, Yuan WH, Sun YC, Chang CY. Preventive vertebroplasty for adjacent vertebral bodies: a good solution to reduce adjacent vertebral fracture after percutaneous vertebroplasty. Am J Neuroradiol. 2012;33:826–32.PubMedCrossRefGoogle Scholar
  99. 99.
    Kaufmann TJ, Jensen ME, Ford G, Gill LL, Marx WF, Kallmes DF. Cardiovascular effects of polymethylmethacrylate use in percutaneous vertebroplasty. Am J Neuroradiol. 2002;23:601–4.PubMedGoogle Scholar
  100. 100.
    Uemura A, Numaguchi Y, Matsusako M, Kobayashi N, Saida Y, Rahman M. Effect on partial pressure of oxygen in arterial blood in percutaneous vertebroplasty. AJNR Am J Neuroradiol. 2007;28:567–9.PubMedGoogle Scholar
  101. 101.
    Mailli L, Filippiadis DK, Brountzos EN, Alexopoulou E, Kelekis N, Kelekis A. Clinical outcome and safety of multilevel vertebroplasty: clinical experience and results. Cardiovasc Interv Radiol. 2012;36:183–91.CrossRefGoogle Scholar
  102. 102.
    Singh AK, Pilgram TK, Gilula LA. Osteoporotic compression fractures: outcomes after single- versus multiple-level percutaneous vertebroplasty 1. Radiology. 2006;238:211–20.PubMedCrossRefGoogle Scholar
  103. 103.
    Chen AT, Cohen DB, Skolasky RL. Impact of nonoperative treatment, vertebroplasty, and kyphoplasty on survival and morbidity after vertebral compression fracture in the medicare population. J Bone Joint Surg Am. 2013;95:1729–36.PubMedCrossRefGoogle Scholar
  104. 104.
    Papanastassiou ID, Phillips FM, Meirhaeghe J, Berenson JR, Andersson GBJ, Chung G, et al. Comparing effects of kyphoplasty, vertebroplasty, and non-surgical management in a systematic review of randomized and non-randomized controlled studies. Eur Spine J. 2012;21:1826–43.PubMedPubMedCentralCrossRefGoogle Scholar
  105. 105.
    Omidi-Kashani F, Samini F, Hasankhani EG, Kachooei AR, Toosi KZ, Golhasani-Keshtan F. Does percutaneous kyphoplasty have better functional outcome than vertebroplasty in single level osteoporotic compression fractures? A comparative prospective study. J Osteoporos. 2013;2013:690329. doi: 10.1155/2013/690329.PubMedPubMedCentralCrossRefGoogle Scholar
  106. 106.
    De Negri P, Tirri T, Paternoster G, Modano P. Treatment of painful osteoporotic or traumatic vertebral compression fractures by percutaneous vertebral augmentation procedures: a nonrandomized comparison between vertebroplasty and kyphoplasty. Clin J Pain. 2007;23:425–30.PubMedCrossRefGoogle Scholar
  107. 107.
    Schofer MD, Efe T, Timmesfeld N, Kortmann H-R, Quante M. Comparison of kyphoplasty and vertebroplasty in the treatment of fresh vertebral compression fractures. Arch Orthop Trauma Surg. 2009;129:1391–9.PubMedCrossRefGoogle Scholar
  108. 108.
    Xing D, Ma J-X, Ma X-L, Wang J, Xu W-G, Chen Y, et al. A meta-analysis of balloon kyphoplasty compared to percutaneous vertebroplasty for treating osteoporotic vertebral compression fractures. J Clin Neurosci. 2013;20:795–803.PubMedCrossRefGoogle Scholar
  109. 109.
    Han S, Wan S, Ning L, Tong Y, Zhang J, Fan S. Percutaneous vertebroplasty versus balloon kyphoplasty for treatment of osteoporotic vertebral compression fracture: a meta-analysis of randomised and non-randomised controlled trials. Int Orthop. 2011;35:1349–58.PubMedPubMedCentralCrossRefGoogle Scholar
  110. 110.
    Diel P, Röder C, Perler G, Vordemvenne T, Scholz M, Kandziora F, et al. Radiographic and safety details of vertebral body stenting: results from a multicenter chart review. BMC Musculoskelet Disord. 2013;14:233.PubMedPubMedCentralCrossRefGoogle Scholar
  111. 111.
    Vanni D, Galzio R, Kazakova A, Pantalone A, Grillea G, Bartolo M, et al. Third-generation percutaneous vertebral augmentation systems. J Spine Surg (Hong Kong). 2016;2:13–20.CrossRefGoogle Scholar
  112. 112.
    Anselmetti GC, Manca A, Marcia S, Chiara G, Marini S, Baroud G, et al. Vertebral augmentation with nitinol endoprosthesis: clinical experience in 40 patients with 1-year follow-up. Cardiovasc Interv Radiol. 2014;37:193–202.CrossRefGoogle Scholar
  113. 113.
    Korovessis P, Vardakastanis K, Repantis T, Vitsas V. Balloon kyphoplasty versus KIVA vertebral augmentation–comparison of 2 techniques for osteoporotic vertebral body fractures: a prospective randomized study. Spine (Phila. Pa. 1976). 2013;38:292–9.CrossRefGoogle Scholar
  114. 114.
    Tutton SM, Pflugmacher R, Davidian M, Beall DP, Facchini FR, Garfin SR. KAST study: the Kiva system as a vertebral augmentation treatment—a safety and effectiveness trial: a randomized, noninferiority trial comparing the Kiva system with balloon kyphoplasty in treatment of osteoporotic vertebral compression fractures. Spine (Phila. Pa. 1976). 2015;40:865–75.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE) 2017

Authors and Affiliations

  1. 1.Interventional Radiology DepartmentStrasbourg University HospitalStrasbourgFrance

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