CardioVascular and Interventional Radiology

, Volume 39, Issue 2, pp 151–160 | Cite as

Radiation-Induced Cataractogenesis: A Critical Literature Review for the Interventional Radiologist

  • Kevin F. Seals
  • Edward W. LeeEmail author
  • Christopher H. Cagnon
  • Ramsey A. Al-Hakim
  • Stephen T. Kee


Extensive research supports an association between radiation exposure and cataractogenesis. New data suggests that radiation-induced cataracts may form stochastically, without a threshold and at low radiation doses. We first review data linking cataractogenesis with interventional work. We then analyze the lens dose typical of various procedures, factors modulating dose, and predicted annual dosages. We conclude by critically evaluating the literature describing techniques for lens protection, finding that leaded eyeglasses may offer inadequate protection and exploring the available data on alternative strategies for cataract prevention.


Clinical practice Radiation protection Radiation Radiation-induced cataracts Lead glasses 



All authors report no financial support.

Compliance with Ethical Standards

Conflict of Interest

All authors declare that they have no conflict of interest.

Ethical Approval

This article does not contain any studies with human participants or animals performed by any of the authors. IRB approval was not required for this literature review.

Informed Consent



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Copyright information

© Springer Science+Business Media New York and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE) 2015

Authors and Affiliations

  • Kevin F. Seals
    • 1
  • Edward W. Lee
    • 1
    Email author
  • Christopher H. Cagnon
    • 2
    • 3
  • Ramsey A. Al-Hakim
    • 1
  • Stephen T. Kee
    • 1
  1. 1.Division of Interventional Radiology, Department of Radiology, UCLA Medical CenterDavid Geffen School of Medicine at UCLALos AngelesUSA
  2. 2.Department of RadiologyUniversity of California at Los AngelesLos AngelesUSA
  3. 3.Department of Biomedical PhysicsUniversity of California at Los AngelesLos AngelesUSA

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