Skip to main content
Log in

Onyx Embolization of Sporadic Angiomyolipoma

  • Case Report
  • Published:
CardioVascular and Interventional Radiology Aims and scope Submit manuscript

Abstract

Percutaneous embolization is the currently preferred treatment of symptomatic or ruptured renal angiomyolipomas (AMLs). Alcohol, microparticles, and coils are usually used. We present what is to our knowledge the first case of successful embolization of a solitary sporadic AML with the use of a new nonadhesive liquid embolic agent (ethylene vinyl alcohol copolymer; Onyx). Onyx injection was slow and controllable and achieved complete tumor devascularization, producing a characteristic appearance like a vascular cast. Short-term follow-up magnetic resonance imaging showed complete tumor necrosis without any recurrent pathologic vessels. The specific features, potential advantages in AML treatment, and technical limitations of this new liquid embolic agent are discussed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

References

  1. Bissler JJ, Kingswood JC (2004) Renal angiomyolipomata. Kidney Int 66:924–934

    Article  PubMed  Google Scholar 

  2. Lenton J, Kessel D, Watkinson AF (2008) Embolization of renal angiomyolipoma: immediate complications and long-term outcomes. Clin Radiol 63:864–870

    Article  CAS  PubMed  Google Scholar 

  3. Oesterling JE, Fishman EK, Goldman SM et al (1986) The management of renal angiomyolipoma. J Urol 135:1121–1124

    CAS  PubMed  Google Scholar 

  4. Mourikis D, Chatziioannou A, Antoniou A et al (1999) Selective arterial embolization in the management of symptomatic renal angiomyolipomas. Eur J Radiol 32:153–159

    Article  CAS  PubMed  Google Scholar 

  5. Ramon J, Rimon U, Garniek A et al (2008) Renal angiomyolipoma: long-term results following selective arterial embolization. Eur Urol (Epub ahead of print)

  6. Rimon U, Duvdevani M, Garniek A et al (2006) Ethanol and polyvinyl alcohol mixture for transcatheter embolization of renal angiomyolipoma. AJR Am J Roentgenol 187:762–768

    Article  PubMed  Google Scholar 

  7. Vanninen RL, Manninen I (2007) Onyx, a new liquid embolic material for peripheral interventions: preliminary experience in aneurysm, pseudoaneurysm, and pulmonary arteriovenous malformation embolization. Cardiovasc Intervent Radiol 30:196–200

    Article  PubMed  Google Scholar 

  8. Tweeddale DN, Dawe CJ, McDonald JR et al (1955) Angiolipoleiomyoma of the kidney: report of a case with observations on histogenesis. Cancer 8:764–770

    Article  CAS  PubMed  Google Scholar 

  9. Ebld J (1998) Angiomyolipoma of the kidney. Semin Diagn Pathol 15:21–40

    Google Scholar 

  10. Eble JN, Amin MB, Young RH (1997) Epithelioid angiomyolipoma of the kidney: a report of five cases with a prominent and diagnostically confusing epithelioid smooth muscle component. Am J Surg Pathol 21:1123–1130

    Article  CAS  PubMed  Google Scholar 

  11. Moorhead JD, Fritzsche P, Hadley HL (1977) Management of hemorrhage secondary to renal angiomyolipoma with selective arterial embolization. J Urol 117:122–123

    CAS  PubMed  Google Scholar 

  12. Yamakado K, Tanaka N, Nakagawa T et al (2002) Renal angiomyolipoma: relationships between tumour size, aneurysm formation, and rupture. Radiology 225:78–82

    Article  PubMed  Google Scholar 

  13. Kothary N, Soulen M, Clark T et al (2005) Renal angiomyolipoma: long-term results after arterial embolization. J Vasc Interv Radiol 16:45–50

    PubMed  Google Scholar 

  14. Katsaridis V, Papagiannaki C, Aimar E (2008) Curative embolization of cerebral arteriovenous malformations (AVMs) with Onyx in 101 patients. Neuroradiology 50:589–597

    Article  PubMed  Google Scholar 

  15. Mounayer C, Hammami N, Piotin M et al (2007) Nidal embolization of brain arteriovenous malformations using Onyx in 94 patients. AJNR Am J Neuroradiol 28:518–523

    CAS  PubMed  Google Scholar 

  16. Vargas HA, Cousins C, Higgins JN et al (2008) Left gastric artery aneurysm: successful embolization with ethylene vinyl alcohol copolymer (Onyx). Cardiovasc Intervent Radiol 31:418–421

    Article  PubMed  Google Scholar 

  17. Abath C, Andrade G, Cavalcanti D et al (2007) Complex renal artery aneurysms: liquids or coils? Tech Vasc Interv Radiol 10:299–307

    Article  PubMed  Google Scholar 

  18. Güven K, Rozanes I, Kayabalı M et al (2008) Endovascular treatment of a superior mesenteric artery aneurysm secondary to Behcet’s disease with Onyx (ethylene vinyl alcohol copolymer). Cardiovasc Intervent Radiol (Epub ahead of print)

  19. Rautio R, Haapanen A (2007) Transcatheter embolization of a renal artery aneurysm using ethylene vinyl alcohol copolymer. Cardiovasc Intervent Radiol 30:300–303

    Article  PubMed  Google Scholar 

  20. Bratby MJ, Lehmann ED, Bottomley J et al (2006) Endovascular embolization of visceral artery aneurysms with ethylene-vinyl alcohol (Onyx): a case series. Cardiovasc Intervent Radiol 29:1125–1128

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Konstantinos Katsanos.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Katsanos, K., Sabharwal, T., Ahmad, F. et al. Onyx Embolization of Sporadic Angiomyolipoma. Cardiovasc Intervent Radiol 32, 1291–1295 (2009). https://doi.org/10.1007/s00270-008-9481-7

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00270-008-9481-7

Keywords

Navigation