CardioVascular and Interventional Radiology

, Volume 30, Issue 4, pp 571–592 | Cite as

Radioembolization with 90Y Microspheres: Angiographic and Technical Considerations

  • Robert J. Lewandowski
  • Kent T. Sato
  • Bassel Atassi
  • Robert K. Ryu
  • Albert A. NemcekJr.
  • Laura Kulik
  • Jean-Francois Geschwind
  • Ravi Murthy
  • William Rilling
  • David Liu
  • Lourens Bester
  • Jose Ignacio Bilbao
  • Andrew S. Kennedy
  • Reed A. Omary
  • Riad Salem
Review/State of the Art


The anatomy of the mesenteric system and the hepatic arterial bed has been demonstrated to have a high degree of variation. This is important when considering pre-surgical planning, catheterization, and trans-arterial hepatic therapies. Although anatomical variants have been well described, the characterization and understanding of regional hepatic perfusion in the context of radioembolization have not been studied with great depth. The purpose of this review is to provide a thorough discussion and detailed presentation of the angiographic and technical aspects of radioembolization. Normal vascular anatomy, commonly encountered variants, and factors involved in changes to regional perfusion in the presence of liver tumors are discussed. Furthermore, the principles described here apply to all liver-directed transarterial therapies.


Brachytherapy Radioembolization Yttrium-90 Liver cancer Embolization SIR-Spheres TheraSphere Selective internal radiation 


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Copyright information

© Springer Science+Business Media, LLC 2007

Authors and Affiliations

  • Robert J. Lewandowski
    • 1
  • Kent T. Sato
    • 1
  • Bassel Atassi
    • 1
  • Robert K. Ryu
    • 1
  • Albert A. NemcekJr.
    • 1
  • Laura Kulik
    • 2
  • Jean-Francois Geschwind
    • 3
  • Ravi Murthy
    • 4
  • William Rilling
    • 5
  • David Liu
    • 6
  • Lourens Bester
    • 7
  • Jose Ignacio Bilbao
    • 8
  • Andrew S. Kennedy
    • 9
  • Reed A. Omary
    • 1
  • Riad Salem
    • 1
    • 10
  1. 1.Department of RadiologySection of Interventional Radiology, Northwestern Memorial Hospital, Robert H. Lurie Comprehensive Cancer CenterChicagoUSA
  2. 2.Department of HepatologyNorthwestern UniversityChicagoUSA
  3. 3.Department of RadiologySection of Interventional Radiology, The Johns Hopkins HospitalBaltimoreUSA
  4. 4.Department of RadiologySection of Interventional Radiology, MD Anderson Cancer Center, University of TexasHoustonUSA
  5. 5.Department of RadiologySection of Interventional Radiology, Medical College of WisconsinMilwaukeeUSA
  6. 6.Inland Imaging LLCAngio/Interventional Section Providence/Sacred Heart Medical CenterSpokaneUSA
  7. 7.Department of Interventional RadiologyUniversity of New South WalesSydneyAustralia
  8. 8.Departamento de RadiologiaClinica Universitaria de NavarraPamplonaSpain
  9. 9.Wake Radiology OncologyCaryUSA
  10. 10.Department of RadiologyChicagoUSA

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