Abstract
The current study describes a new noninvasive device for measuring central ejection dP/dt (dP/dtejc). The device consists of a sphygmonometric arm cuff and an array of proprietary sensors attached to the arm at the antecubital space over the brachial artery, and a computerized monitoring system. Noninvasive systolic pressure wave forms are generated by measuring time delay between the first sensor on the array serving as a reference and onset of brachial artery flow in subsequent sensors during controlled upper arm deflation. The delay decreases with falling cuff pressure so that the plot of pressure versus time delays yields ascending portion of arterial wave form. The present study describes our initial experience in 16 patients with coronary artery disease undergoing percutaneous transluminal coronary angioplasty. Noninvasive measurements were performed at baseline, after balloon inflation and at the end of catheterization. Mean balloon occlusion time was 37 ± 10 s. In 14 of 16 patients, dP/dtejc decreased from 149 ± 29 to 120 ± 33 (p < 0.0002). In 11 of 14, an immediate return to near baseline values after deflation (136±28 p < 0.001) occurred.
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Gorenberg, M., Marmor, A. & Rotstein, H. A New Noninvasive Device for Measuring Central Ejection dP/dt. Cardiovasc Eng 4, 305–310 (2004). https://doi.org/10.1007/s00270-005-8756-5
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DOI: https://doi.org/10.1007/s00270-005-8756-5