Abstract
A 73-year-old man with hepatitis-C-related cirrhosis and an elevated alpha-fetoprotein level and tumor in segment 3 of his liver was referred for interventional radiologic treatment. He was not a candidate for surgical resection due to impaired liver function and his personal preferences. On conventional ultrasonography no lesion could be detected, but the tumor was clearly depicted by intra-arterial carbon-dioxide-enhanced ultrasonography. Radiofrequency ablation was performed safely and accurately under the guidance of carbon-dioxide-enhanced ultrasonography. By concomitant performance of transcatheter arterial chemoembolization with radiofrequency ablation, extensive necrosis was obtained and adequate tumor volume reduction achieved with only one treatment session.
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McGhana JP, Dodd GD 3rd (2001) Radiofrequency ablation of the liver: current status. AJR Am J Roentgenol 176:3–16
Lin SM, Lin CJ, Lin CC, et al. (2005) Randomised controlled trial comparing percutaneous radiofrequency thermal ablation, percutaneous ethanol injection, and percutaneous acetic acid injection to treat hepatocellular carcinoma of 3 cm or less. Gut 54:1151–1156
Matsuda Y, Yabuuchi I (1986) Hepatic tumors: US contrast enhancement with CO2 microbubbles. Radiology 161:701–705
Ohmoto K, Tsuzuki M, Yamamoto S (1999) Percutaneous microwave coagulation therapy with intraperitoneal saline infusion for hepatocellular carcinoma in the hepatic dome. AJR Am J Roentgenol 173:65–66
Koda M, Ueki M, Maeda T, et al. (2004) Percutaneous sonographically guided radiofrequency ablation with artificial pleural effusion for hepatocellular carcinoma located under the diaphragm. AJR Am J Roentgenol 183:583–588
Ohmoto K, Mimura N, Iguchi Y, et al. (2002) CT-guided percutaneous ethanol injection therapy for ultrasonically invisible hepatocellular carcinoma. Hepatogastroenterology 49:297–299
Minami Y, Kudo M, Kawasaki T, et al. (2004) Treatment of hepatocellular carcinoma with percutaneous radiofrequency ablation: Usefulness of contrast harmonic sonography for lesions poorly defined with B-mode sonography. AJR Am J Roentgenol 183:153–156
Ikeda K, Saitoh S, Koida I, et al. (1994) Imaging diagnosis of small hepatocellular carcinoma. Hepatology 20:82–87
Numata K, Tanaka K. Kiba T, et al. (2001) Nonresectable hepatocellular carcinoma: Improved percutaneous ethanol injection guided by CO2-enhanced sonography. AJR Am J Roentgenol 177:789–798
Chen RC, Liao LY, Wang CS, et al. (2003) Carbon dioxide-enhanced sonographically guided percutaneous ethanol injection: Treatment of patients with viable and recurrent hepatocellular carcinoma. AJR Am J Roentgenol 181:1647–1652
Hashimoto M, Watanabe O, Hirano Y, et al. (1997) Use of carbon dioxide microbubble-enhanced sonographic angiography for transcatheter arterial chemoembolization of hepatocellular carcinoma. AJR Am J Roentgenol 169:1307–1310
Kitamoto M, Imagawa M, Yamada H, et al (2003) Radiofrequency ablation in the treatment of small hepatocellular carcinoma: Comparison of the radiofrequency effect with and without chemoembolization. AJR Am J Roentgenol 181:997–1003
Veltri A, Moretto P, Doriguzzi A, et al. (2005) Radiofrequency thermal ablation (RFA) after transarterial chemoembolization (TACE) as a combined therapy for unresectable non-early hepatocellular carcinoma (HCC). Eur Radiol 14:1–9
Ahrar K, Gupta S (2003) Hepatic artery embolization for hepatocellular carcinoma: Technique, patient selection, and outcomes. Surg Oncol Clin North Am 12:105–126
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Ohmoto, K., Yoshioka, N., Tomiyama, Y. et al. Use of Intra-Arterial Carbon-Dioxide-Enhanced Ultrasonography for Guidance of Radiofrequency Ablation and Transcatheter Arterial Chemoembolization in Hepatocellular Carcinoma. Cardiovasc Intervent Radiol 29, 1111–1113 (2006). https://doi.org/10.1007/s00270-005-0285-8
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DOI: https://doi.org/10.1007/s00270-005-0285-8