Skip to main content
Log in

Angioplasty or Stenting in Adult Coarctation of the Aorta? A Retrospective Single Center Analysis Over a Decade

  • Clinical Investigations
  • Published:
CardioVascular and Interventional Radiology Aims and scope Submit manuscript

Abstract

For over 11 years, endovascular treatment by angioplasty (PTA) alone or stenting of adult coarctation at a single center was evaluated. We retrospectively reviewed 28 consecutive patients (31 interventions), median age 25 years, treated between 1991 and 2002, 20 of whom had native coarctation. Thirteen patients had PTA alone (16 procedures) (10 “kissing balloon” angioplasty comprising 12 interventions, and 3 single balloon angioplasty comprising 4 interventions) and 15 patients were stented (15 procedures), including 6 secondary and 9 primary stents. There were no procedural or 30-day complications. For the whole group, the median follow-up was 6.6 years (range 1–10 years). In the PTA group, median follow-up was 9 years (range 3–10) and in the stenting group it was 3 years (range 1–5). There were 9 restenoses in the PTA group (6 after “kissing balloons” and 3 after single balloon) comprising 56% of the angioplasties (9/16 procedures). There was 1 restenosis in the stenting group diagnosed at computed tomography (CT). The patient was clinically well. For the whole group there were significant reductions in systolic blood pressure (BP) (p = 0.0003), diastolic BP (p = 0.004) and number of drugs per patient (p = 0.045) at latest follow-up post-treatment. Five patients discontinued therapy. Analysis of the groups revealed that the reduction of systolic and diastolic BP and number of drugs did not reach statistical significance in the PTA group but were significant in the stent group. The endovascular management of adult coarctation is safe. Stents may be more effective than PTA alone but longer-term follow-up of stents is required.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Figure 1
Figure 2

Similar content being viewed by others

References

  1. PS Rao (1995) ArticleTitleCoarctation of the aorta. Semin Nephrol 15 87–105

    Google Scholar 

  2. M Campbell (1970) ArticleTitleNatural history of coarctation of the aorta. Br Heart J 32 633–640 Occurrence Handle1:STN:280:CS6D3cnitVw%3D Occurrence Handle5470045

    CAS  PubMed  Google Scholar 

  3. S Westaby B Parnell RB Pridie (1987) ArticleTitleCoarctation of the aorta in adults. Clinical presentation and results of surgery. J Cardiovasc Surg 28 124–127

    Google Scholar 

  4. WJ Wells TW Prendergast F Berdjis D Brandl PE Lange R Hetzer VA Starnes (1996) ArticleTitleRepair of coarctation of the aorta in adults: The fate of systolic hypertension. Ann Thorac Surg 61 1168–1171 Occurrence Handle10.1016/0003-4975(96)00008-2 Occurrence Handle1:STN:280:BymC1c3itVE%3D Occurrence Handle8607677

    Article  CAS  PubMed  Google Scholar 

  5. SR Schuster RE Gross (1961) ArticleTitleSurgery for coarctation of the aorta: A review of 500 cases. J Thoracic Cardiovasc Surg 43 54–69

    Google Scholar 

  6. J. de Giovanni (2001) ArticleTitleCovered stents in the treatment of aortic coarctation. J Interven Cardiol 14 187–190 Occurrence Handle1:STN:280:DC%2BD38zht1Shtw%3D%3D

    CAS  Google Scholar 

  7. DA Harrison PR McLaughlin C Lazzam M Connelly LN Benson (2001) ArticleTitleEndovascular stents in the management of coarctation of the aorta in the adolescent and adult: One year follow-up. Heart 85 561–566 Occurrence Handle10.1136/heart.85.5.561 Occurrence Handle1:STN:280:DC%2BD3M3ms1Wjsg%3D%3D Occurrence Handle11303011

    Article  CAS  PubMed  Google Scholar 

  8. GP Ussia M Marasini G Pongiglione (2001) ArticleTitleParaplegia following percutaneous balloon angioplasty of the aortic coarctation: A case report. Catheter Cardiovasc Intervent 54 510–513 Occurrence Handle10.1002/ccd.1322 Occurrence Handle1:STN:280:DC%2BD3Mnps12ltg%3D%3D

    Article  CAS  Google Scholar 

  9. T Ino M Kishiro M Okubo K Akimoto K Nishimoto K Yabuta S Kawasaki Y Hosoda (1998) ArticleTitleDilatation mechanism of balloon angioplasty in children: Assessment by angiography and intravascular ultrasound. Cardiovasc Intervent Radiol 21 102–108

    Google Scholar 

  10. JK Harrison KH Shekh CJ Davidson KB Kisslo ME Leithe SI Himmelstein RJ Kanter TM Bashore (1990) ArticleTitleBalloon angioplasty of coarctation of the aorta evaluated with intravascular ultrasound imaging. J Am Coll Cardiol 15 906–909

    Google Scholar 

  11. A Rothman F Ricou RG Weintraub R Crowley R Arcangeli T Shiota J Zhang DJ Sahn (1992) ArticleTitleIntraluminal ultrasound imaging through a balloon dilatation catheter in an animal model of coarctation of the aorta. Circulation 85 2291–2295 Occurrence Handle1:STN:280:By2B2svlsF0%3D Occurrence Handle1591843

    CAS  PubMed  Google Scholar 

  12. AD Tong A Rothman RL Atkinson T Shiota F Ricou DJ Sahn (1995) ArticleTitleIntravascular ultrasound imaging of coarctation of the aorta: Animal and human studies. Am J Card Imaging 9 250–256 Occurrence Handle1:STN:280:BymC3M3jsVM%3D Occurrence Handle8680141

    CAS  PubMed  Google Scholar 

  13. S Sohn A Rothman T Shiota G Luk A Tong RE Swensson DJ Sahn (1994) ArticleTitleAcute and follow-up intravascular ultrasound findings after balloon dilatation of coarctation of the aorta. Circulation 90 340–347 Occurrence Handle1:STN:280:ByuB1MfhslU%3D Occurrence Handle8026016

    CAS  PubMed  Google Scholar 

  14. JM Isner RF Donaldson D Fulton I Bhan DD Payne RJ Cleveland (1987) ArticleTitleCystic medial necrosis in coarctation of the aorta: A potential factor contributing to adverse consequences observed after percutaneous balloon angioplasty of coarctation sites. Circulation 75 689–695 Occurrence Handle1:STN:280:BiiC2MbptFI%3D Occurrence Handle2951035

    CAS  PubMed  Google Scholar 

  15. AG Magee G Brezezinska-Rajszys SA Qureshi E Rosenthal M Zubrzycka J Ksiazyk M Tynan (1999) ArticleTitleStent implantation for aortic coarctation and recoarctation. Heart 82 600–606 Occurrence Handle1:STN:280:DyaK1Mvlslaiug%3D%3D Occurrence Handle10525517

    CAS  PubMed  Google Scholar 

  16. BD Thanopoulos L Hadjinikolaou GN Konstadopoulou GS Tsaousis F Triposkiadis P Spirou (2000) ArticleTitleStent treatment for coarctation of the aorta: Intermediate term follow-up and technical considerations. Heart 84 65–70 Occurrence Handle10.1136/heart.84.1.65 Occurrence Handle1:STN:280:DC%2BD3czitFajtg%3D%3D Occurrence Handle10862593

    Article  CAS  PubMed  Google Scholar 

  17. AC Marshall CA Perry JF Keane JE Lock (2000) ArticleTitleEarly results and medium-term follow-up of stent implantation for mild residual or recurrent aortic coarctation. Am Heart J 139 1054–1060 Occurrence Handle10.1067/mhj.2000.106616 Occurrence Handle1:STN:280:DC%2BD3c3oslarsQ%3D%3D Occurrence Handle10827387

    Article  CAS  PubMed  Google Scholar 

  18. J Suarez de Lezo M Pan M Romero A Medina J Segura M Lafuente D Pavlovic E Hernandez F Melian J Espada (1999) ArticleTitleImmediate and follow-up findings after stent treatment for severe coarctation of aorta. Am J Cardiol 83 400–406 Occurrence Handle10.1016/S0002-9149(98)00877-7 Occurrence Handle1:STN:280:DyaK1M7ntVCnug%3D%3D Occurrence Handle10072232

    Article  CAS  PubMed  Google Scholar 

  19. MR Ebeid LR Prieto LA Latson (1997) ArticleTitleUse of balloon-expandable stents for coarctation of the aorta: Initial results and intermediate-term follow-up. J Am Coll Cardiol 30 1847–1852

    Google Scholar 

  20. JW Kirklin BG. Barratt-Boyes (1993) Cardiac surgery: morphology, diagnostic criteria, natural history, techniques, results and indications, 2nd ed Churchill Livingston New York 1285

    Google Scholar 

  21. K Forfang H Rostad S Sorland (1981) ArticleTitleCoarctation of the aorta: Follow-up of 218 patients operated on after 13 years of age. Acta Med Scand (Suppl) 645 15–22 Occurrence Handle1:STN:280:Bi6B3cznslU%3D

    CAS  Google Scholar 

  22. ED Foster (1984) ArticleTitleReoperation for aortic coarctation. Ann Thorac Surg 38 81–89 Occurrence Handle1:STN:280:BiuB3s%2FjtFM%3D Occurrence Handle6375606

    CAS  PubMed  Google Scholar 

  23. RH Beekman AP Rocchini DM Behrendt A Rosenthal (1981) ArticleTitleReoperation for coarctation of the aorta. Am J Cardiol 48 1108–1114

    Google Scholar 

  24. LA III Brewer RG Fosburg GA Mulder JJ Verska (1972) ArticleTitleSpinal cord complications following surgery for coarctation of the aorta: A study of 66 cases. J Thorac Cardiovasc Surg 64 368–381 Occurrence Handle5054875

    PubMed  Google Scholar 

  25. JE Connolly (1998) ArticleTitleHume Memorial Lecture. Prevention of spinal cord complications in aortic surgery. Am J Surg 176 92–101 Occurrence Handle10.1016/S0002-9610(98)00133-0 Occurrence Handle1:STN:280:DyaK1cvgslKhug%3D%3D Occurrence Handle9737610

    Article  CAS  PubMed  Google Scholar 

  26. AP Kappetein AH Zwinderman AJ Bogers J Rohmer HA Huysmans (1994) ArticleTitleMore than thirty-five years of coarctation repair: An unexpected high relapse rate. J Thorac Cardiovasc Surg 107 87–95 Occurrence Handle1:STN:280:ByuC3M7mtFM%3D Occurrence Handle8283924

    CAS  PubMed  Google Scholar 

  27. AJ Paddon AA Nicholson DF Ettles SJ Travis JF Dyet (2000) ArticleTitleLong-term follow-up of percutaneous balloon angioplasty in adult aortic coarctation. Cardiovasc Intervent Radiol 23 364–367

    Google Scholar 

  28. ME Fawzy V Sivanandam O Galal B Dunn A Patel A Rifai W von Sinner Z Al Halees B Khan (1997) ArticleTitleOne- to ten-year follow-up of balloon angioplasty of native coarctation of the aorta in adolescents and adults. J Am Coll Cardiol 30 1542–1546

    Google Scholar 

  29. R Schrader Jacobi Bussmann W-D Kadel V . C (1995) ArticleTitleLong-term effects of balloon coarctation angioplasty on arterial blood pressure in adolescent and adult patients. Cathet Cardiovasc Diagn 36 220–225 Occurrence Handle1:STN:280:BymC38jit1M%3D Occurrence Handle8542628

    CAS  PubMed  Google Scholar 

  30. J Koerselman H de Vries W Jaarsma L Muyldermans JMPG Ernst HWM. Plokker (2000) ArticleTitleBalloon angioplasty of coarctation of the aorta: A safe alternative for surgery in adults: Immediate and mid-term results. Cathet Cardiovasc Int 50 28–33 Occurrence Handle10.1002/(SICI)1522-726X(200005)50:1<28::AID-CCD6>3.3.CO;2-4 Occurrence Handle1:STN:280:DC%2BD3c3ns1GrtQ%3D%3D

    Article  CAS  Google Scholar 

  31. Z Bulbul E Bruckheimer JC Love JT Fahey WE Hellenbrand (1996) ArticleTitleImplantation of balloon-expandable stents for coarctation of the aorta: Implantation data and short-term results. Cathet Cardiovasc Diagn 39 36–42 Occurrence Handle10.1002/(SICI)1097-0304(199609)39:1<36::AID-CCD7>3.3.CO;2-Z Occurrence Handle1:STN:280:ByiD38fptlU%3D Occurrence Handle8874943

    Article  CAS  PubMed  Google Scholar 

  32. MA Hamdan S Maheshwari JT Fahey WE Hellenbrand (2001) ArticleTitleEndovascular stents for coarctation of the aorta: Initial results and intermediate-term follow-up. J Am Coll Cardiol 38 1518–1523

    Google Scholar 

  33. ME Fawzy B Dunn O Galal N Wilson A Shaikh R Sriram CM Duran (1992) ArticleTitleBalloon coarctation angioplasty in adolescents and adults: Early and intermediate results. Am Heart J 124 167–171 Occurrence Handle1:STN:280:By2A3M3ktlw%3D Occurrence Handle1535473

    CAS  PubMed  Google Scholar 

  34. S Tyagi R Arora UA Kaul KK Sethi DS Ghambir M Khalilullah (1992) ArticleTitleBalloon angioplasty of native coarctation of the aorta in adolescents and young adults. Am Heart J 123 674–680 Occurrence Handle1:STN:280:By2C2s%2FmvVw%3D Occurrence Handle1531722

    CAS  PubMed  Google Scholar 

  35. DG Ray R Subramanyan T Titus J Tharakan J Joy CG Venkitachalam KG Balakrishnan (1992) ArticleTitleBalloon angioplasty for native coarctation of the aorta in children and adults: Factors determining the outcome. Int J Cardiol 36 273–281

    Google Scholar 

  36. M Ledesma C Alva FD Gomez A Sanchez-Soberanis DY Diaz C Benitez-Perez R Herrera-Franco R Arguero T Feldman (2001) ArticleTitleResults of stenting for aortic coarctation. Am J Cardiol 88 460–462 Occurrence Handle10.1016/S0002-9149(01)01705-2 Occurrence Handle1:STN:280:DC%2BD3Mvps1Gmsg%3D%3D Occurrence Handle11545780

    Article  CAS  PubMed  Google Scholar 

  37. C Duke SA Qureshi (2001) ArticleTitleAortic coarctation and recoarctation: To stent or not to stent. J Intervent Cardiol 3 283–298

    Google Scholar 

  38. A Beitzke JI Stein A Gamillscheg B Rigler (1997) ArticleTitleDissection of the descending aorta after balloon angioplasty of the native coarctation. Pediatr Cardiol 18 222–225

    Google Scholar 

  39. U Aydogan A Dindar L Gurgan T Cantez (1995) ArticleTitleLate development of dissecting aneurysm following balloon angioplasty of native aortic coarctation. Cathet Cardiovasc Diagn 36 226–229 Occurrence Handle1:STN:280:BymC38jit1w%3D Occurrence Handle8542629

    CAS  PubMed  Google Scholar 

  40. S Balaji R Oommen PG Rees (1991) ArticleTitleAortic rupture during balloon dilatation of recoarctation. Br Heart J 65 100–101 Occurrence Handle1:STN:280:By6A38bht1A%3D Occurrence Handle1831032

    CAS  PubMed  Google Scholar 

  41. J Cheatham S Fletcher C Foreman S Froemming (1998) ArticleTitleEarly experience using endovascular stents in children with coarctation of the aorta: Promising results  but proceed with caution [abstract]. Cardiol Young 9 IssueIDsuppl 1 11

    Google Scholar 

  42. SE Fletcher JP Cheatham S Froeming (1998) ArticleTitleAortic aneurysm following primary balloon angioplasty and secondary endovascular stent placement in the treatment of native coarctation of the aorta [see comments]. Cathet Cardiovasc Diagn 44 40–44 Occurrence Handle10.1002/(SICI)1097-0304(199805)44:1<40::AID-CCD10>3.3.CO;2-Y Occurrence Handle1:STN:280:DyaK1c3mtFWnug%3D%3D Occurrence Handle9600521

    Article  CAS  PubMed  Google Scholar 

  43. J Gunn TJ Cleveland P Gaines (1999) ArticleTitleCovered stent to treat coexistent coarctation and aneurysm of the aorta in a young man. Heart 82 351 Occurrence Handle1:STN:280:DyaK1Mzoslagtg%3D%3D Occurrence Handle10455088

    CAS  PubMed  Google Scholar 

  44. S Rao (1997) ArticleTitleStents in treatment of aortic coarctation. Editorial comment. JACC 30 1853–1855 Occurrence Handle1:STN:280:DyaK1c%2FksFKrtw%3D%3D Occurrence Handle9385918

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Sumaira Macdonald.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Macdonald, S., Thomas, S., Cleveland, T. et al. Angioplasty or Stenting in Adult Coarctation of the Aorta? A Retrospective Single Center Analysis Over a Decade . CVIR 26, 357–364 (2003). https://doi.org/10.1007/s00270-003-2709-7

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00270-003-2709-7

Keywords

Navigation