Abstract. Interleukin-6 (IL-6) levels in cancer tissues of 32 patients with colorectal cancer were measured and analyzed in relation to the clinicopathologic findings. The IL-6 level in cancer tissues was 81.1 ± 118.0 pg/mg protein, which was significantly higher than the 11.2 ± 20.8 pg/mg protein in normal colorectal tissues (
p = 0.028). IL-6 levels in cancer tissues showed no correlation with the incidence of venous invasion, lymphatic invasion, lymph node involvement, or liver metastasis. The IL-6 level in cancer tissue tended to decrease as the cancer penetration extended. Our results suggest that IL-6 may play a role in human colorectal cancer growth.
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Komoda, H., Tanaka, Y., Honda, M. et al. Interleukin-6 Levels in Colorectal Cancer Tissues. World J. Surg. 22, 895–898 (1998). https://doi.org/10.1007/s002689900489
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DOI: https://doi.org/10.1007/s002689900489