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Cost-Effective Surgical Management of Liver Disease Amidst a Financial Crisis

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Abstract

Background

Intraoperative use of specialized equipment and disposables contributes to the increasing cost of modern liver surgery. As a response to the recent severe financial crisis in our country we have employed a highly standardized protocol of liver resection that minimizes intraoperative and postoperative costs. Our goal is to evaluate cost-effectiveness of this protocol.

Study design

We evaluated retrospectively all patients who underwent open hepatic resections for 4 years. All resections were performed by the same surgical team under selective hepatic vascular exclusion, i.e., occlusion of the hepatoduodenal ligament and the major hepatic veins, occasionally combined with extrahepatic ligation of the ipsilateral portal vein. Sharp parenchymal transection was performed with a scalpel and hemostasis was achieved with sutures without the use of energy devices. In each case we performed a detailed analysis of costs and surgical outcomes.

Results

Our cohort included 146 patients (median age 63 years). 113 patients were operated for primary or metastatic malignancies and 33 for benign lesions. Operating time was 121 ± 21 min (mean ± SD), estimated blood loss was 310 ± 159 ml (mean ± SD), and hospital stay was 7 ± 5 days (mean ± SD). Six patients required admission in the ICU postoperatively. 90-day mortality was 2.74 %, and 8.9 % of patients developed grade III/IV postoperative complications (Clavien–Dindo classification). Total in-hospital cost excluding physician fees was 6987.63 ± 3838.51 USD (mean ± SD).

Conclusions

Our analysis suggests that, under pressing economic conditions, the proposed surgical protocol can significantly lessen the financial burden of liver surgery without compromising patient outcomes.

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References

  1. Sato M, Tateishi R, Yasunaga H et al (2012) Mortality and morbidity of hepatectomy, radiofrequency ablation and embolization for hepatocellular carcinoma: a national survey of 54,145 patients. J Gastroenterol 47(10):1125–1133

    Article  PubMed  Google Scholar 

  2. Abu Hilal M, Di Fabio F, Syed S et al (2013) Assessment of the financial implications for laparoscopic liver surgery: a single center UK cost analysis for minor and major hepatectomy. Surg Endosc. 27(7):2542–2550

    Article  PubMed  Google Scholar 

  3. Pelletier JS, Gill RS, Shi X et al (2013) Robotic-assisted hepatic resection: a systematic review. Int J Med Robot. 9(3):262–267

    Article  PubMed  Google Scholar 

  4. Souliotis K, Golnas C, Tountas Y, et al. (2015) Informal payments in the Greek health sector amid the financial crisis: old habits die last… Eur J Health Econ. 17(2):159–170

    Article  PubMed  Google Scholar 

  5. Smyrniotis V, Arkadopoulos N, Kostopanagiotou G et al (2005) Sharp liver transection versus clamp crushing technique in liver resections: a prospective study. Surgery 137(3):306–311

    Article  PubMed  Google Scholar 

  6. Clavien PA, Barkun J, de Oliveira ML et al (2009) The Clavien–Dindo classification of surgical complications: five-year experience. Ann Surg 250(2):187–196

    Article  PubMed  Google Scholar 

  7. IBM SPSS Statistics Software, ver. 20 for Macintosh. http://www-01.ibm.com/ software/analytics/spss/products/statistics

  8. Jarnagin WR, Gonen M, Fong Y et al (2002) Improvement in perioperative outcome after hepatic resection: analysis of 1,803 consecutive cases over the past decade. Ann Surg 236(4):397–406

    Article  PubMed  PubMed Central  Google Scholar 

  9. Di Saverio S, Catena F, Filicori F et al (2012) Predictive factors of morbidity and mortality in grade IV and V liver trauma undergoing perihepatic packing: a single institution 14 years experience at European trauma center. Injury 43(9):1347–1354

    Article  PubMed  Google Scholar 

  10. Kenjo A, Miyata H, Gotoh M et al (2014) Risk stratification of 7,732 hepatectomy cases in 2011from the National Clinical Database for Japan. J Am Coll Surg 218(3):412–422

    Article  PubMed  Google Scholar 

  11. Gustafson JD, Fox JP, Ouellette JR et al (2012) Open versus laparoscopic liver resection: looking beyond the immediate postoperative period. Surg Endosc 26(2):468–472

    Article  PubMed  Google Scholar 

  12. Ganger M, Rheault M, Dubuc J (1992) Laparoscopic partial hepatectomy for liver tumor [abstract]. Surg Endosc 6:97

    Google Scholar 

  13. Azagra JS, Goergen M, Gilbart E, Jacobs D (1996) Laparoscopic anatomical (hepatic) left lateral segmentectomy—technical aspects. Surg Endosc 10(7):758–761

    Article  CAS  PubMed  Google Scholar 

  14. Hanly EJ, Talamini MA (2004) Robotic abdominal surgery. Am J Surg 188(4A Suppl):19S–26S

    Article  PubMed  Google Scholar 

  15. Alkhalili E, Berber E (2014) Laparoscopic liver resection for malignancy: a review of the literature. World J Gastroenterol 20(37):13599–13606

    Article  PubMed  PubMed Central  Google Scholar 

  16. Buell JF, Cherqui D, Geller DA et al (2009) The international position on laparoscopic liver surgery: the Louisville Statement, 2008. Ann Surg 250(5):825–830

    Article  PubMed  Google Scholar 

  17. Bodzin AS, Leiby BE, Ramirez CG et al (2014) Liver resection using cavitron ultrasonic surgical aspirator (CUSA) versus harmonic scalpel: a retrospective cohort study. Int J Surg. 12(5):500–503

    Article  PubMed  Google Scholar 

  18. Milisevic M, Bulajic P, Zuvela M et al (2007) A radiofrequency-assisted minimal blood loss liver parenchyma dissection technique. Dig. Surg. 24(4):306–313

    Article  Google Scholar 

  19. Richter S, Kollmar O, Schuld J et al (2009) Randomized clinical trial of efficacy and costs of three dissection devices in liver resection. Br J Surg 96(6):593–601

    Article  CAS  PubMed  Google Scholar 

  20. Bhojani FD, Fox A, Pitzul K et al (2012) Clinical and economic comparison of laparoscopic to open liver resections using a 2-to-1 matched pair analysis: an institutional experience. J Am Coll Surg 214(2):184–195

    Article  PubMed  Google Scholar 

  21. Kobayashi S, Nagano H, Marubashi S et al (2011) Experience with the use of fibrin sealant plus polyglycolic acid felt at the cut surface of the liver in laparoscopic hepatectomy. Surg Endosc 25(11):3590–3596

    Article  PubMed  Google Scholar 

  22. Ji WB, Wang HG, Zhao ZM et al (2011) Robotic-assisted laparoscopic anatomic hepatectomy in China: initial experience. Ann Surg 253(2):342–348

    Article  PubMed  Google Scholar 

  23. Barbash GI, Glied SA (2010) New technology and health care costs–the case of robot-assisted surgery. N Engl J Med 363(8):701–704

    Article  CAS  PubMed  Google Scholar 

  24. Gurusamy KS, Pamecha V, Sharma D, Davidson BR (2009) Techniques for liver parenchymal transection in liver resection. Cochrane Database Syst Rev. 1:CD006880

    PubMed  Google Scholar 

  25. Vanounou T, Steel JL, Nguyen KT et al (2010) Comparing the clinical and economic impact of laparoscopic versus open liver resection. Ann Surg Oncol 17(4):998–1009

    Article  PubMed  Google Scholar 

  26. Polignano FM, Quyn AJ, de Figueiredo RS et al (2008) Laparoscopic versus open liver segmentectomy: prospective, case-matched, intention-to-treat analysis of clinical outcomes and cost effectiveness. Surg Endosc 22(12):2564–2570

    Article  PubMed  Google Scholar 

  27. Medbery RL, Chadid TS, Sweeney JF et al (2014) Laparoscopic vs open right hepatectomy: a value-based analysis. J Am Coll Surg 218(5):929–939

    Article  PubMed  Google Scholar 

  28. Zhang X, Yang J, Yan L et al (2014) Comparison of laparoscopy-assisted and open donor right hepatectomy: a prospective case-matched study from China. J Gastrointest Surg. 18(4):744–750

    Article  PubMed  Google Scholar 

  29. Franken C, Lau B, Putchakayala K, DiFronzo LA (2014) Comparison of short-term outcomes in laparoscopic vs open hepatectomy. JAMA Surg. 149(9):941–946

    Article  PubMed  Google Scholar 

  30. Savlid M, Strand AH, Jansson A et al (2013) Transection of the liver parenchyma with an ultrasound dissector or a stapler device: results of a randomized clinical study. World J Surg 37(4):799–805. doi:10.1007/s00268-012-1884-6

    Article  PubMed  Google Scholar 

  31. Lee KF, Wong J, Ng W et al (2009) Feasibility of liver resection without the use of the routine Pringle maneuver: an analysis of 248 consecutive cases. HPB (Oxford). 11(4):332–338

    Article  PubMed  PubMed Central  Google Scholar 

  32. Smyrniotis VE, Kostopanagiotou GG, Gamaletsos EL et al (2002) Total versus selective hepatic vascular exclusion in major liver resections. Am J Surg 183(2):173–178

    Article  PubMed  Google Scholar 

  33. Smyrniotis V, Kostopanagiotou G, Lolis E et al (2003) Effects of hepatovenous backflow on ischemic-reperfusion injuries in liver resections with the pringle maneuver. J Am Coll Surg 197(6):949–954

    Article  PubMed  Google Scholar 

  34. Yin Z, Fan X, Ye H et al (2013) Short- and long-term outcomes after laparoscopic and open hepatectomy for hepatocellular carcinoma: a global systematic review and meta-analysis. Ann Surg Oncol 20(4):1203–1215

    Article  PubMed  Google Scholar 

Download references

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Correspondence to Georgios Gemenetzis.

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Arkadopoulos, N., Gemenetzis, G., Danias, N. et al. Cost-Effective Surgical Management of Liver Disease Amidst a Financial Crisis. World J Surg 40, 1695–1701 (2016). https://doi.org/10.1007/s00268-016-3440-2

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  • DOI: https://doi.org/10.1007/s00268-016-3440-2

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