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Sensitivity and Specificity of Red Cell Distribution Width in Diagnosing Acute Mesenteric Ischemia in Patients with Abdominal Pain

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Abstract

Background

We investigated the utility of the red cell distribution width (RDW) in diagnosing acute mesenteric ischemia (AMI) in patients with abdominal pain.

Methods

The patients were divided into two groups in this retrospective case–control study: patients with AMI and patients with abdominal pain who did not require urgent surgery. Venous blood was collected from the patients upon admission to the emergency department, and abdominal computed tomography angiography was performed. The RDW and hematological and biochemical parameters of the groups were compared. The primary outcome was AMI among the patients with abdominal pain. The secondary outcome was mortality, complaint period, and size of ischemia/necrosis among the AMI patients.

Results

The RDW, white blood cell lactate dehydrogenase, and blood urea nitrogen of the patients with AMI were significantly different from those of the control group. When the average RDW (15.04 %) of the patients with AMI was used as a cut-off value, the sensitivity, specificity, positive likelihood ratio (+LR), and negative likelihood (−LR) were 40.8 %, 81.2 %, 2.17, and 0.73, respectively. When patients with AMI and anemia were included in the group, the sensitivity and specificity values did not change. There was no relation between the RDW and mortality, size of the ischemia/necrosis, and complaint period. Furthermore, there was no significant difference in the average RDW between the patients with ischemia/necrosis in the small intestine only and those with ischemia/necrosis in the colon.

Conclusion

The RDW on admission is of marginal help to diagnose AMI among patients with abdominal pain.

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Disclosure

No conflicts of interest exist. We have disclosed to study participants potential investigator conflicts of interest.

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Authors and Affiliations

  1. Department of General Surgery, School of Medicine, Ataturk University, 25070, Erzurum, Turkey

    Abdullah Kisaoglu, Bunyami Ozogul & Sabri Selcuk Atamanalp

  2. Department of Emergency Medicine, School of Medicine, Ataturk University, Erzurum, Turkey

    Atif Bayramoglu, Kenan Atac & Mucahit Emet

Authors
  1. Abdullah Kisaoglu
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  2. Atif Bayramoglu
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  3. Bunyami Ozogul
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  4. Kenan Atac
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  5. Mucahit Emet
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  6. Sabri Selcuk Atamanalp
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Correspondence to Abdullah Kisaoglu.

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Kisaoglu, A., Bayramoglu, A., Ozogul, B. et al. Sensitivity and Specificity of Red Cell Distribution Width in Diagnosing Acute Mesenteric Ischemia in Patients with Abdominal Pain. World J Surg 38, 2770–2776 (2014). https://doi.org/10.1007/s00268-014-2706-9

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  • DOI: https://doi.org/10.1007/s00268-014-2706-9

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