Colectomy in Intensive Care Patients: Operative Findings and Outcomes
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With a critical illness, intestinal complications are associated with high morbidity and mortality.
Operative findings and outcomes of 77 intensive care unit (ICU) patients treated with colectomy are described.
Three conditions led to colectomy: sepsis (S group; n = 31), fulminant Clostridium difficile colitis (Cl group; n = 25), and cardiovascular surgery (CV group; n = 21). The median Acute Physiology and Chronic Health score was >25 in all groups. Thickening and distension of the colon was more frequent in the Cl group (p = 0.001), and ischemia was more frequent in the S and CV groups (p < 0.001). Widespread necrosis was more frequent in the CV patients (p = 0.001). The kappa value for ischemic operative findings and histologic necrosis was 0.64 (95 % confidence interval 0.49–0.79). Hospital mortality was 35 % without multiple organ failure (MOF) (n = 31) and 74 % with MOF (n = 46) (p < 0.001). Overall, 38 % were alive at the 1-year follow-up.
Although colectomy in ICU patients is associated with high hospital mortality, patients who survive beyond their hospital stay have a good 1-year outcome
KeywordsIntensive Care Unit Patient Clostridium Difficile Infection Multiple Organ Failure Ischemic Colitis Pseudomembranous Colitis
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