World Journal of Surgery

, Volume 36, Issue 10, pp 2288–2299 | Cite as

Regenerative Surgery: Tissue Engineering in General Surgical Practice

  • Victor W. WongEmail author
  • Derrick C. Wan
  • Geoffrey C. Gurtner
  • Michael T. Longaker


Tissue engineering is a broad interdisciplinary field that aims to develop complex tissue and organ constructs through a combination of cell-, biomaterial-, and molecular-based approaches. This approach has the potential to transform the surgical treatment for diseases including trauma, cancer, and congenital malformations. A fundamental knowledge of key concepts in regenerative medicine is imperative for surgeons to maintain a leading role in developing and implementing these technologies. Researchers have started to elucidate the biologic mechanisms that maintain organ homeostasis throughout life, indicating that humans may have the latent capacity to regenerate complex tissues. By exploiting this intrinsic potential of the body, we can move even closer to developing functional, autologous replacement parts for a wide range of surgical diseases.


Tissue Engineering Stem Cell Population Ventral Hernia Repair Abdominal Wall Hernia Esophageal Epithelial Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Conflict of interest

The authors have no conflicts of interest to disclose.


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Copyright information

© Société Internationale de Chirurgie 2012

Authors and Affiliations

  • Victor W. Wong
    • 1
    • 2
    Email author
  • Derrick C. Wan
    • 2
  • Geoffrey C. Gurtner
    • 2
  • Michael T. Longaker
    • 2
  1. 1.Department of SurgeryOregon Health & Science UniversityPortlandUSA
  2. 2.Department of SurgerySchool of Medicine, Stanford UniversityStanfordUSA

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