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Effects of Emptying Function of Remaining Stomach on QOL in Postgastrectomy Patients

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Abstract

Background

Attention has recently focused on decreased quality of life (QOL) that occurs in postgastrectomy patients. We verified how gastric emptying function affected QOL.

Methods

Subjects were 72 consecutive patients after gastrectomy for cancer, including 25 after distal gastrectomy (DG), 18 after proximal gastrectomy (PG), 16 after pylorus-preserving gastrectomy (PpG), and 13 after total gastrectomy (TG). Using the 13C breath test method, 13CO2 levels in breath were measured over 2 h, and T max was determined. Questionnaires (Japanese versions of the Short-Form 36 [SF-36] and Gastrointestinal Symptom Rating Scale [GSRS]) were used to analyze QOL and correlations between questionnaire results and T max.

Results

Mean T max (min) for each procedure was 15.4 for DG, 21.1 for PG, 41.3 for PpG, and 10.4 for TG. T max differed between procedures, but not between survey periods. SF-36 was not correlated with T max, whereas GSRS showed a difference in diarrhea and total score between procedures, but not between survey periods. In addition, GSRS correlated with T max for abdominal pain, indigestion, and total score. The total scores showed a significant symptom aggregation in patients with T max less than 21 min.

Conclusions

Gastrointestinal symptoms in postgastrectomy patients were associated with the function of the remaining stomach. The 13C breath test is useful for objectively assessing such symptoms.

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Authors and Affiliations

  1. Second Department of Surgery, Tokyo Women’s Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, Japan

    Masaru Hayami, Akiyoshi Seshimo, Kunitomo Miyake & Shingo Kameoka

  2. Medical Research Institute, Tokyo Women’s Medical University, Tokyo, 162-8666, Japan

    Satoru Shimizu

Authors
  1. Masaru Hayami
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  2. Akiyoshi Seshimo
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  3. Kunitomo Miyake
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  4. Satoru Shimizu
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  5. Shingo Kameoka
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Correspondence to Akiyoshi Seshimo.

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Hayami, M., Seshimo, A., Miyake, K. et al. Effects of Emptying Function of Remaining Stomach on QOL in Postgastrectomy Patients. World J Surg 36, 373–378 (2012). https://doi.org/10.1007/s00268-011-1379-x

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